A Study to Evaluate the Safety of THR-149 in Subjects With Diabetic Macular Edema (DME)
Public ClinicalTrials.gov record NCT03511898. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1, Open-label, Multicenter, Dose Escalation Study to Evaluate the Safety of a Single Intravitreal Injection of THR-149 for the Treatment of Diabetic Macular Edema (DME)
Study identification
- NCT ID
- NCT03511898
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- ThromboGenics
- Industry
- Enrollment
- 12 participants
Conditions and interventions
Interventions
- THR-149 dose level 1 Drug
- THR-149 dose level 2 Drug
- THR-149 dose level 3 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 17, 2018
- Primary completion
- May 21, 2019
- Completion
- May 21, 2019
- Last update posted
- Jun 12, 2019
2018 – 2019
United States locations
- U.S. sites
- 7
- U.S. states
- 5
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retina Consultants of Arizona | Phoenix | Arizona | 85053 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Mid Atlantic Retina | Huntingdon Valley | Pennsylvania | 19006 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Retinal Research Center, PLLC | Austin | Texas | 78705 | — |
| Retina Consultants of Houston | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03511898, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 12, 2019 · Synced Jun 26, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03511898 live on ClinicalTrials.gov.