Study of ASTX029 in Subjects With Advanced Solid Tumors
Public ClinicalTrials.gov record NCT03520075. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1-2 Study of the Safety, Pharmacokinetics, and Activity of ASTX029 in Subjects With Advanced Solid Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a first-in-human, open-label, multicenter, Phase 1-2 study to assess the safety, pharmacokinetics, pharmacodynamics, and preliminary clinical activity of ASTX029 administered orally to participants with advanced solid malignancies who are not candidates for approved or available therapies.
Study identification
- NCT ID
- NCT03520075
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 192 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 7, 2018 (Actual)
- Primary completion
- Aug 1, 2024 (Actual)
- Completion
- Mar 3, 2025 (Actual)
- Last update posted
- Jul 3, 2025
2018 – 2025
United States locations
- U.S. sites
- 19
- U.S. states
- 11
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | — |
| University of Southern California Norris Comprehensive Cancer Center Site#114 | Los Angeles | California | 90033 | — |
| Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute Site# 107 | Los Angeles | California | 90048 | — |
| Hoag Memorial Hospital Site#115 | Newport Beach | California | 92658 | — |
| University of California Davis Medical Center Site #121 | Sacramento | California | 95817 | — |
| California Pacific Medical Center - Sutter Pacific Medical Center Site#117 | San Francisco | California | 94115-2378 | — |
| Smilow Cancer Hospital at Yale New Haven Site#105 | New Haven | Connecticut | 06510 | — |
| Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | — |
| The Sidney Kimmel Comprehensive Cancer Center Site#106 | Baltimore | Maryland | 21231 | — |
| Massachusetts General Hospital Site#103 | Boston | Massachusetts | 02114 | — |
| Dana Farber Cancer Institute Site#104 | Boston | Massachusetts | 02215 | — |
| University of Michigan Rogel Cancer Center Site #113 | Ann Arbor | Michigan | 48109 | — |
| Columbia University Irving Medical Center - Herbert Irving Pavilion Site#112 | New York | New York | 10032 | — |
| Providence Portland Medical Center Site #118 | Portland | Oregon | 97223 | — |
| Oregon Health and Science University Site #122 | Portland | Oregon | 97239 | — |
| University of Pennsylvania-Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| The University of Texas MD Anderson Cancer Center Site#111 | Houston | Texas | 77030 | — |
| START - South Texas Accelerated Research Therapeutics, LLC Site# 101 | San Antonio | Texas | 78229 | — |
| Virginia Cancer Specialists Site#102 | Fairfax | Virginia | 22031 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03520075, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 3, 2025 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03520075 live on ClinicalTrials.gov.