A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis
Public ClinicalTrials.gov record NCT03524092. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm, Placebo-Controlled Maintenance Study of Mirikizumab in Patients With Moderately to Severely Active Ulcerative Colitis (LUCENT 2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of mirikizumab as maintenance therapy in participants who completed as clinical responders in the prior 12-week induction study LUCENT-1 (NCT03518086).
Study identification
- NCT ID
- NCT03524092
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,328 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 19, 2018 (Actual)
- Primary completion
- Nov 3, 2021 (Actual)
- Completion
- Feb 17, 2025 (Actual)
- Last update posted
- May 13, 2026
2018 – 2025
United States locations
- U.S. sites
- 57
- U.S. states
- 24
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Digestive Health Specialists of the Southeast | Dothan | Alabama | 36305 | — |
| Dcr-Pi, Pc | Litchfield Park | Arizona | 85340 | — |
| Maricopa Integrated Health System | Phoenix | Arizona | 85008 | — |
| Physicians Research Group | Tempe | Arizona | 85284 | — |
| Valley Gastroenterology | Arcadia | California | 91006 | — |
| Care Access Research | Berkeley | California | 94705 | — |
| Om Research, LLC | Lancaster | California | 93534 | — |
| California Medical Research Associates | Northridge | California | 91324 | — |
| Clinical Applications Laboratories, Inc. | San Diego | California | 92103 | — |
| UCSF Medical Center at Mission Bay | San Francisco | California | 94158 | — |
| Direct Helpers Research Center | Hialeah | Florida | 33012 | — |
| Nature Coast Clinical Research, LLC | Inverness | Florida | 34452 | — |
| SIH Research, LLC | Kissimmee | Florida | 34741 | — |
| Research Associates of South Florida, LLC | Miami | Florida | 33134 | — |
| Wellness Clinical Research | Miami Lakes | Florida | 33016 | — |
| Center for Interventional Endoscopy | Orlando | Florida | 32803 | — |
| Clintheory Healthcare | Orlando | Florida | 32818 | — |
| Gastroenterology Associates of Pensacola, PA | Pensacola | Florida | 32503 | — |
| Florida Medical Clinic LLC | Zephyrhills | Florida | 33542-7505 | — |
| Digestive Healthcare of Georgia | Atlanta | Georgia | 30309 | — |
| Grand Teton Research Group | Idaho Falls | Idaho | 83404 | — |
| NorthShore University HealthSystem | Evanston | Illinois | 60201 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| Cotton-O'Neil Clinical Research Center, Digestive Health | Topeka | Kansas | 66606 | — |
| Texas Digestive Disease Consultants | Baton Rouge | Louisiana | 70809 | — |
| Delta Research Partners LLC | Monroe | Louisiana | 71201 | — |
| Nola Research Works, LLC | New Orleans | Louisiana | 70125 | — |
| Clinical Research Institute of Michigan, LLC | Chesterfield | Michigan | 48047 | — |
| Henry Ford Health System | Novi | Michigan | 48377 | — |
| Gastroenterology Associates of Western Michigan, P.L.C. | Wyoming | Michigan | 49519 | — |
| Huron Gastroenterology Associates | Ypsilanti | Michigan | 48197 | — |
| MNGI Digestive Health - Plymouth Endoscopy Center & Clinic | Plymouth | Minnesota | 55446 | — |
| Care Access Research LLC | Jackson | Mississippi | 39206 | — |
| Digestive Health Specialists | Tupelo | Mississippi | 38801 | — |
| Northwell Health | Great Neck | New York | 11021 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| University of North Carolina Center for Inflammatory Bowel Disease | Chapel Hill | North Carolina | 27599 | — |
| Carolina Digestive Diseases and Endoscopy Center | Greenville | North Carolina | 27834 | — |
| Paramount Medical Research | Middleburg Heights | Ohio | 44130 | — |
| Care Access - Youngstown | Poland | Ohio | 44514 | — |
| Central Sooner Research | Norman | Oklahoma | 73071 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Digestive Disease Associates | Wyomissing | Pennsylvania | 19610 | — |
| Midwest Medical Care | Sioux Falls | South Dakota | 57108 | — |
| Gastro One | Germantown | Tennessee | 38138 | — |
| Galen Medical Group | Hixson | Tennessee | 37343 | — |
| Digestive Health Associates of Texas | Garland | Texas | 75044 | — |
| Houston Methodist Research Ins | Houston | Texas | 77030 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77043 | — |
| Gastroenterology Research of San Antonio | San Antonio | Texas | 78229 | — |
| Southern Star Research Institute, LLC | San Antonio | Texas | 78229 | — |
| Texas Digestive Disease Consultants | Southlake | Texas | 76092 | — |
| Care Access Research LLC - Salt Lake City | Ogden | Utah | 84403 | — |
| Emeritas Research Group | Leesburg | Virginia | 20176 | — |
| The Gastroenterology Group, P.C. | Reston | Virginia | 20191 | — |
| Carilion Clinic | Roanoke | Virginia | 24016 | — |
| Wisconsin Center for Advanced Research | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 328 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03524092, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 13, 2026 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03524092 live on ClinicalTrials.gov.