ClinicalTrials.gov record
Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration
ClinicalTrials.gov ID: NCT03525600
Public ClinicalTrials.gov record NCT03525600. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multi-Center, Randomized, Double-Masked, Sham-Controlled Study to Compare the Efficacy and Safety of Intravitreal Pegcetacoplan Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
Study identification
- NCT ID
- NCT03525600
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Apellis Pharmaceuticals, Inc.
- Industry
- Enrollment
- 621 participants
Conditions and interventions
Conditions
Interventions
- APL-2 Drug
- Sham Procedure Other
Drug · Other
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 30, 2018
- Primary completion
- Jun 20, 2021
- Completion
- Jun 19, 2022
- Last update posted
- Jun 17, 2023
2018 – 2022
United States locations
- U.S. sites
- 73
- U.S. states
- 24
- U.S. cities
- 64
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Research Institute | Phoenix | Arizona | 85014 | — |
| Associated Retina Consultants, Ltd | Phoenix | Arizona | 85020 | — |
| Retina Institute of California dba Acuity Eye Grp | Arcadia | California | 91007 | — |
| California Retina Consultants | Bakersfield | California | 93309 | — |
| Retina Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| The Retina Partners | Encino | California | 91436 | — |
| The Gavin Herbert Eye Institute/UC Irvine | Irvine | California | 92697 | — |
| Northern California Retina Vitreous Associates | Mountain View | California | 94040 | — |
| Retina Institute of California Medical Group | Palm Desert | California | 92260 | — |
| Byers Eye Institute at Standford, Stanford School of Medicine | Palo Alto | California | 94303 | — |
| Retina Consultants San Diego | Poway | California | 92064 | — |
| Retina Consultants of Southern California | Redlands | California | 92374 | — |
| California Retina Consultants | Santa Barbara | California | 93103 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| Danbury Eye Physicians & Surgeons, P.C. - Danbury | Danbury | Connecticut | 06810 | — |
| New England Retina Associates | Hamden | Connecticut | 06518 | — |
| Retina Group of New England,PC | Waterford | Connecticut | 06385 | — |
| Florida Eye Microsurgical Institute, Inc. | Boynton Beach | Florida | 33426 | — |
| Pinnacle Research Institute | Fort Lauderdale | Florida | 33309 | — |
| Retina Health Center | Fort Myers | Florida | 33907 | — |
| Bascom Palmer Eye Institute | Palm Beach Gardens | Florida | 33418 | — |
| Eye Associates of Pinellas | Pinellas Park | Florida | 33782 | — |
| East Florida Eye Institute | Stuart | Florida | 34994 | — |
| Southern Vitreoretinal Associates | Tallahassee | Florida | 32308 | — |
| Retina Associates of Florida | Tampa | Florida | 33609 | — |
| University of South Florida (USF) Eye Institute | Tampa | Florida | 33612 | — |
| Southeast Retina Center, PC | Augusta | Georgia | 30909 | — |
| Georgia Retina | Marietta | Georgia | 30060 | — |
| Midwest Eye Institute | Indianapolis | Indiana | 46290 | — |
| Sabates Eye Center | Leawood | Kansas | 66211 | — |
| Elman Retina Group, PA | Baltimore | Maryland | 21236 | — |
| Cumberland Valley Retina Consultants, PC | Hagerstown | Maryland | 21740 | — |
| Mid Atlantic Retina Specialists | Hagerstown | Maryland | 21740 | — |
| Retina Specialists | Towson | Maryland | 21204 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| New England Retina Consultants, PC | Springfield | Massachusetts | 01107 | — |
| Associated Retinal Consultants, P.C | Grand Rapids | Michigan | 49546 | — |
| Retina Specialists of Michigan / Foundation for Vision | Grand Rapids | Michigan | 49546 | — |
| Retina Consultants of Michigan | Southfield | Michigan | 48034 | — |
| Associated Retinal Consultants PC | Traverse City | Michigan | 49686 | — |
| Sierra Eye Associates | Reno | Nevada | 89503 | — |
| Retina Associates of New Jersey (NJ Retina) | Teaneck | New Jersey | 07666 | — |
| Long Island Vitreoretinal Consultants | Great Neck | New York | 11021 | — |
| Vitreous Retina Macula Consultants of NY | New York | New York | 10022 | — |
| Western Carolina Retinal Associates | Asheville | North Carolina | 28803 | — |
| Charlotte Eye Ear Nose and Throat Associates, PS | Charlotte | North Carolina | 28210 | — |
| Graystone Eye | Hickory | North Carolina | 28602 | — |
| Retina Associates of Cleveland, Inc. | Cleveland | Ohio | 44122 | — |
| Retina Associates of Cleveland, Inc | Cleveland | Ohio | 44122 | — |
| Retina Associates of Cleveland | Cleveland | Ohio | 44130 | — |
| Cleveland Clinic, Cole Eye Institute | Cleveland | Ohio | 44195 | — |
| The Ohio State University | Columbus | Ohio | 43212 | — |
| Retina Associates of Cleveland, Inc. | Youngstown | Ohio | 44505 | — |
| Retina Northwest, PC | Portland | Oregon | 97221 | — |
| Eye Health Northwest | Portland | Oregon | 97225 | — |
| Mid Atlantic Retina | Philadelphia | Pennsylvania | 19006 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Tennessee Retina, PC | Nashville | Tennessee | 37203 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Southwest Retina Specialists | Amarillo | Texas | 79106 | — |
| Retina Consultants of Austin (Retina Research Center) | Austin | Texas | 78705 | — |
| Retina Consultants of Houston, PA | Houston | Texas | 77030 | — |
| Valley Retina Institute, PA | McAllen | Texas | 78503 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| Retinal Consultants of San Antonio | San Antonio | Texas | 78240 | — |
| Retina Consultants of Houston | The Woodlands | Texas | 77384 | — |
| Retina Associates of Utah, PC | Murray | Utah | 84107 | — |
| University of Virginia | Charlottesville | Virginia | 22903 | — |
| The Retina Group of Washington | Fairfax | Virginia | 22031 | — |
| Virginia Retina Center | Warrenton | Virginia | 20186 | — |
| Vitreoretinal Associates of Washington | Bellevue | Washington | 98004 | — |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | — |
| University of Wisconsin | Madison | Wisconsin | 53715 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 68 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03525600, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 17, 2023 · Synced May 12, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03525600 live on ClinicalTrials.gov.