Efficacy and Safety of Intravenous Neridronic Acid in CRPS
Public ClinicalTrials.gov record NCT03530345. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double-blind, Placebo-controlled Trial Investigating the Efficacy and Safety of Intravenous Neridronic Acid in Subjects With Complex Regional Pain Syndrome (CRPS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The aim of this trial was to investigate the efficacy and safety of intravenous neridronic acid in subjects with Complex Regional Pain Syndrome (CRPS). The trial consisted of an Enrollment Period lasting up to 60 days, Treatment Period A consisting of 4 infusions (neridronic acid or placebo) over 10 days, and a Follow-up Period 1 until Week 26. At Week 26, participants not meeting the pre-specified criteria to continue into Treatment Period B continued in Follow-up Period 2 until Week 52. Participants meeting the pre-specified criteria entered the open-label Treatment Period B with 4 additional infusions (neridronic acid) over 10 days and follow-up visits until Week 52.
Study identification
- NCT ID
- NCT03530345
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 182 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 30, 2018 (Actual)
- Primary completion
- Jul 31, 2019 (Actual)
- Completion
- Jul 31, 2019 (Actual)
- Last update posted
- Aug 6, 2020
2018 – 2019
United States locations
- U.S. sites
- 39
- U.S. states
- 23
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| US015 - Tennessee Valley Pain Consultants | Huntsville | Alabama | 35801 | — |
| US043 - Horizon Research Partners | Mobile | Alabama | 36605 | — |
| US045 - Holland Center for Family Health | Peoria | Arizona | 85381 | — |
| US003 - HealthStar Research | Hot Springs | Arkansas | 71913 | — |
| US049 - Orange County Research Institute | Anaheim | California | 92801 | — |
| US053 - Core Healthcare Group | Cerritos | California | 90703 | — |
| US013 - Inland Pain Medicine | Colton | California | 92324 | — |
| US044 - The Helm Center for Pain Management | Laguna Woods | California | 92637 | — |
| US052 - Providere' Research Inc. | West Covina | California | 91790 | — |
| US036 - Denver Back Pain Specialists | Greenwood Village | Colorado | 80111 | — |
| US007 - Neurology Offices of South Florida | Boca Raton | Florida | 33428 | — |
| US030 - Gulfcoast Clinical Research Center | Fort Myers | Florida | 33912 | — |
| US004 - The Chappel Group Research | Kissimmee | Florida | 34744 | — |
| US023 - AGR Research | Lake Worth | Florida | 33462 | — |
| US020 - SIMEDHealth | Ocala | Florida | 34474 | — |
| US012 - NeuroMedical Research Center | Panama City | Florida | 32405 | — |
| US046 - Clinical Research of West Florida, Inc. | Tampa | Florida | 33603 | — |
| US027 - Drug Studies America | Marietta | Georgia | 30060 | — |
| US041 - Better Health Clinical Research, Inc. | Newnan | Georgia | 30265 | — |
| US032 - Millennium Pain Center | Bloomington | Illinois | 61704 | — |
| US011 - Otrimed Corporation | Edgewood | Kentucky | 41017 | — |
| US040 - Regeneris Medical | North Attleboro | Massachusetts | 02760 | — |
| Us054 - Aa Mrc | Flint | Michigan | 48504 | — |
| US025 - Oakland Medical Research | Troy | Michigan | 48085 | — |
| US009 - Elite Clinical Research | Jackson | Mississippi | 39202 | — |
| US017 - Jackson Anesthesia Pain Center | Jackson | Mississippi | 39202 | — |
| US033 - Galen Research | Chesterfield | Missouri | 63005 | — |
| US050 - Premier Pain Centers | Shrewsbury | New Jersey | 07702 | — |
| US029 - Dent Neurologic Institute | Amherst | New York | 14226 | — |
| US038 - DiGiovanna Institute For Medical Education | North Massapequa | New York | 11758 | — |
| US022 - The Neurological Institute | Charlotte | North Carolina | 28204 | — |
| US047 - The Center for Clinical Research | Winston-Salem | North Carolina | 27103 | — |
| US005 - Hometown Urgent Care and Research | Dayton | Ohio | 45424 | — |
| US021 - SP Research PLLC | Oklahoma City | Oklahoma | 73112 | — |
| US028 - Founders Research Corporation | Philadelphia | Pennsylvania | 19152 | — |
| US018 - Carolinas Center for Advanced Management of Pain | Spartanburg | South Carolina | 29303 | — |
| US055 - Diversified Medical Practices | Houston | Texas | 77057 | — |
| US048 - Axios Research | Salt Lake City | Utah | 84106 | — |
| US037 - Clinical Research Partners | Richmond | Virginia | 23235 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03530345, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 6, 2020 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03530345 live on ClinicalTrials.gov.