ClinicalTrials.gov record
A Clinical Trial to Learn About the Study Medicine Called Maplirpacept (PF-07901801), Alone and When Used in Combination With Other Medicines to Treat Participants With Advanced Hematological Malignancies, Including Lymphoma, Leukemia and Multiple Myeloma
ClinicalTrials.gov ID: NCT03530683
Public ClinicalTrials.gov record NCT03530683. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1a/1b Dose-Escalation and Expansion Trial of TTI-622 in Patients With Advanced Hematologic Malignancies, Including Lymphoma, Leukemia, and Multiple Myeloma
Study identification
- NCT ID
- NCT03530683
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 189 participants
Conditions and interventions
Interventions
- Maplirpacept (PF-07901801) Drug
- Azacitidine Drug
- Venetoclax Drug
- Carfilzomib Drug
- Dexamethasone Drug
- Anti-CD20 Targeting agent Drug
- Isatuximab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 13, 2018
- Primary completion
- Jul 17, 2024
- Completion
- Jul 17, 2024
- Last update posted
- Sep 2, 2024
2018 – 2024
United States locations
- U.S. sites
- 62
- U.S. states
- 18
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Keck Hospital of USC | Los Angeles | California | 90033 | — |
| LAC+USC Medical Center | Los Angeles | California | 90033 | — |
| USC/Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Keck Hospital of USC Pasadena | Pasadena | California | 91105 | — |
| Colorado Blood Cancer Institute | Denver | Colorado | 80218 | — |
| HealthONE Presbyterian/St. Luke's Medical Center | Denver | Colorado | 80218 | — |
| Christiana Care Health Services | Newark | Delaware | 19713 | — |
| Christiana Care Hematology Oncology - Helen F Graham Cancer Center | Newark | Delaware | 19713 | — |
| Medical Oncology Hematology Consultants, PA, Helen F. Graham Cancer Center | Newark | Delaware | 19713 | — |
| Christiana Care Health Services - Christiana Hospital | Newark | Delaware | 19718 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Tampa General Hospital Cancer Institute | Tampa | Florida | 33606 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| Blood and Marrow Transplant Group of Georgia | Atlanta | Georgia | 30342 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| Indiana Blood & Marrow Transplantation | Indianapolis | Indiana | 46237 | — |
| Indiana Blood and Marrow Transplantation-Administrative Offices | Indianapolis | Indiana | 46237 | — |
| Indiana Blood and Marrow Transplantation-Clinic | Indianapolis | Indiana | 46237 | — |
| Norton Cancer Institute, St Matthews Campus | Louisville | Kentucky | 40207 | — |
| Norton Cancer Institute, St. Matthews Campus, Attn. Becky Champion, PharmD | Louisville | Kentucky | 40207 | — |
| Norton Diagnostic Center-Dupont (PET Scans) | Louisville | Kentucky | 40207 | — |
| Norton Women & Children's Hospital | Louisville | Kentucky | 40207 | — |
| University of Michigan Hospitals | Ann Arbor | Michigan | 48109 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Karmanos Cancer Institute Weisberg Cancer Treatment Center | Farmington Hills | Michigan | 48334 | — |
| Memorial Sloan Kettering Cancer Center at Basking Ridge | Basking Ridge | New Jersey | 07920 | — |
| Summit Medical Group Cancer Center | Florham Park | New Jersey | 07932 | — |
| Memorial Sloan Kettering Cancer Center at Monmouth | Middletown | New Jersey | 07748 | — |
| Memorial Sloan Kettering Bergen | Montvale | New Jersey | 07645 | — |
| Memorial Sloan Kettering Cancer Center at Montvale | Montvale | New Jersey | 07645 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Memorial Sloan Kettering Cancer Center at Commack | Commack | New York | 11725 | — |
| Memorial Sloan Kettering Cancer Center at Westchester | Harrison | New York | 10604 | — |
| Memorial Sloan Kettering Cancer Center - Investigational Drug Service Pharmacy | Long Island City | New York | 11101 | — |
| Memorial Sloan Kettering Cancer Center - David H. Koch Center | New York | New York | 10021 | — |
| Memorial Sloan Kettering Cancer Center (Outpatient Center) | New York | New York | 10065 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Memorial Sloan Kettering Cancer Center at Nassau | Uniondale | New York | 11553 | — |
| Novant Health Cancer Institute - Research Office | Charlotte | North Carolina | 28204 | — |
| Novant Health Cancer Institute Hematology - Charlotte | Charlotte | North Carolina | 28204 | — |
| Novant Health Presbyterian Medical Center | Charlotte | North Carolina | 28204 | — |
| Novant Health Cancer Institute - Research Office | Winston-Salem | North Carolina | 27103 | — |
| Novant Health Cancer Institute Hematology - Forsyth | Winston-Salem | North Carolina | 27103 | — |
| Novant Health Forsyth Medical Center | Winston-Salem | North Carolina | 27103 | — |
| Gabrail Cancer Center Research | Canton | Ohio | 44718 | — |
| Sidney Kimmel Cancer Center, Clinical Trials Organization | Philadelphia | Pennsylvania | 19107 | — |
| Sidney Kimmel Cancer Center, Research Support Services | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University - Clinical Research Institute | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University Investigational Drug Services | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University, Investigational Drug Service | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University, Medical Oncology | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| West Penn Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| Prisma Health, Institute for Translational Oncology Research, Clinical Research Unit | Greenville | South Carolina | 29605 | — |
| Prisma Health-Upstate Cancer Institute | Greenville | South Carolina | 29605 | — |
| University of TN Medical Center | Knoxville | Tennessee | 37920 | — |
| Oncology Consultants P.A. | Houston | Texas | 77030 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03530683, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 2, 2024 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03530683 live on ClinicalTrials.gov.