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Terminated Phase 2 Interventional Results available

Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart Failure

ClinicalTrials.gov ID: NCT03532009

Public ClinicalTrials.gov record NCT03532009. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 4:30 AM EST

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Official title

A Phase II, Randomised, Double-Blind, Placebo Controlled, Parallel-Group, Multicentre, Three Month Duration Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart Failure

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is an international, multicentre, parallel-group, randomised, double-blind, placebo controlled, phase II study to evaluate the benefits and risks of using sodium zirconium cyclosilicate (ZS) to initiate and intensify renin angiotensin aldosterone system inhibitor (RAASi) therapy in heart failure patients.

Study identification

NCT ID
NCT03532009
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
182 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 150 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 26, 2018 (Actual)
Primary completion
May 22, 2020 (Actual)
Completion
May 22, 2020 (Actual)
Last update posted
Jun 15, 2021

2018 – 2020

United States locations

U.S. sites
14
U.S. states
11
U.S. cities
14
Facility City State ZIP Site status
Research Site National City California 91950 —
Research Site Stanford California 94305 —
Research Site Waterbury Connecticut 06708 —
Research Site Miami Florida 33133 —
Research Site New Smyrna Beach Florida 32169 —
Research Site Port Charlotte Florida 33952 —
Research Site Indianapolis Indiana 46260 —
Research Site Alexandria Louisiana 71301 —
Research Site Boston Massachusetts 02115 —
Research Site Flint Michigan 48504 —
Research Site Brooklyn New York 11204 —
Research Site Wyomissing Pennsylvania 19610 —
Research Site Rapid City South Dakota 57701 —
Research Site El Paso Texas 79935 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 62 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03532009, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 15, 2021 · Synced Nov 7, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03532009 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →