Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Active, not recruiting Phase 4 Interventional

Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS

ClinicalTrials.gov ID: NCT03535298

Public ClinicalTrials.gov record NCT03535298. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 7:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for the Treatment of Relapsing-Remitting Multiple Sclerosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The DELIVER-MS study seeks to answer the question: Does early treatment with highly effective DMT improve the prognosis for people with MS? This is an area of significant controversy and no data currently exist to guide treatment choices for patients and clinicians. The study results will help guide overall treatment philosophy and will be applicable not only to a wide range of existing therapies but also to new therapies, meeting a significant unmet need in patient decision making and aiding the decision for medication approval by third parties.

Study identification

NCT ID
NCT03535298
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 4
Lead sponsor
The Cleveland Clinic
Other
Enrollment
800 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 60 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 2, 2019
Primary completion
Jul 29, 2027
Completion
Jul 29, 2027
Last update posted
Aug 30, 2026

2019 – 2027

United States locations

U.S. sites
15
U.S. states
8
U.S. cities
14
Facility City State ZIP Site status
University of Colorado-Anschutz Medical Campus Aurora Colorado 80045
University of Minnesota Minneapolis Minnesota 55455
Mayo Clinic Rochester Minnesota 55902
Cleveland Clinic Lou Ruvo Center for Brain Health Las Vegas Nevada 89106
University of Buffalo Buffalo New York 14202
University Rochester Medical Center Rochester New York 14642
University of Cincinnati Cincinnati Ohio 45267
Cleveland Clinic Cleveland Ohio 44195
Ohio Health Columbus Ohio 43214
UT-Austin Austin Texas 78712
Baylor College of Medicine, Houston Houston Texas 77030
UTHealth-Houston Houston Texas 77030
University of Virginia Charlottesville Virginia 22903
Virginia Commonwealth University Richmond Virginia 23284
University of Wisconsin-Madison Madison Wisconsin 53705

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03535298, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 30, 2026 · Synced Sep 1, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03535298 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →