A Study Designed to Evaluate the Safety and Efficacy of Venetoclax Plus Dexamethasone (VenDex) Compared With Pomalidomide Plus Dexamethasone (PomDex) in Participants With t(11;14)-Positive Relapsed or Refractory Multiple Myeloma.
Public ClinicalTrials.gov record NCT03539744. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Open Label Study of Venetoclax and Dexamethasone Compared With Pomalidomide and Dexamethasone in Subjects With t(11;14)-Positive Relapsed or Refractory Multiple Myeloma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A study designed tocompare progression-free survival (PFS) in participants with t(11;14)-positive MM treated with venetoclax in combination with dexamethasone versus pomalidomide in combination with dexamethasone.
Study identification
- NCT ID
- NCT03539744
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 265 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 22, 2018 (Actual)
- Primary completion
- Aug 2026 (Estimated)
- Completion
- Nov 2027 (Estimated)
- Last update posted
- Jun 19, 2025
2018 – 2027
United States locations
- U.S. sites
- 19
- U.S. states
- 15
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Duplicate_University of Arizona Cancer Center - North Campus /ID# 218407 | Tucson | Arizona | 85719-1478 | — |
| VA Central California Health Care System /ID# 200047 | Fresno | California | 93703-2223 | — |
| University of California, Los Angeles /ID# 171524 | Los Angeles | California | 90095 | — |
| Rocky Mountain Regional VA Medical Center/Eastern Colorado Health Care System /ID# 222904 | Aurora | Colorado | 80045 | — |
| Mayo Clinic /ID# 200075 | Jacksonville | Florida | 32224 | — |
| Cleveland Clinic Florida /ID# 208884 | Weston | Florida | 33331-3609 | — |
| Duplicate_Norton Cancer Institute /ID# 200834 | Louisville | Kentucky | 40202-3700 | — |
| University of Maryland, Baltimore /ID# 217422 | Baltimore | Maryland | 21201 | — |
| Boston Medical Center /ID# 223606 | Boston | Massachusetts | 02118 | — |
| Barbara Ann Karmanos Cancer In /ID# 201377 | Detroit | Michigan | 48201 | — |
| Duplicate_Henry Ford Hospital /ID# 171531 | Detroit | Michigan | 48202 | — |
| Mayo Clinic - Rochester /ID# 201091 | Rochester | Minnesota | 55905-0001 | — |
| Columbia University Medical Center /ID# 200715 | New York | New York | 10032-3729 | — |
| Fairview Hospital - Moll Pavilion /ID# 208919 | Cleveland | Ohio | 44111-5605 | — |
| Cleveland Clinic Main Campus /ID# 202247 | Cleveland | Ohio | 44195 | — |
| UPMC Hillman Cancer Ctr /ID# 200063 | Pittsburgh | Pennsylvania | 15232 | — |
| MD Anderson Cancer Center at Texas Medical Center /ID# 200060 | Houston | Texas | 77030-4000 | — |
| Huntsman Cancer Institute /ID# 218406 | Salt Lake City | Utah | 84112-5500 | — |
| VA Puget Sound Health Care System /ID# 222708 | Seattle | Washington | 98108-1597 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 161 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03539744, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 19, 2025 · Synced Nov 1, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03539744 live on ClinicalTrials.gov.