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Completed Phase 1Phase 2 Interventional Results available

To Evaluate Safety, Tolerability, and Clinical Activity of the Antibody-drug Conjugate, GSK2857916 Administered in Combination With Lenalidomide Plus Dexamethasone (Arm A), or in Combination With Bortezomib Plus Dexamethasone (Arm B) in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

ClinicalTrials.gov ID: NCT03544281

Public ClinicalTrials.gov record NCT03544281. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 3:12 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I/II, Open-label, Dose Escalation and Expansion Study to Evaluate Safety, Tolerability, and Clinical Activity of the Antibody-Drug Conjugate GSK2857916 Administered in Combination With Lenalidomide Plus Dexamethasone (Arm A), or Bortezomib Plus Dexamethasone (Arm B) in Participants With Relapsed / Refractory Multiple Myeloma - DREAMM-6

Study identification

NCT ID
NCT03544281
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
GlaxoSmithKline
Industry
Enrollment
153 participants

Conditions and interventions

Interventions

  • Belantamab mafodotin Drug
  • Lenalidomide Drug
  • Dexamethasone Drug
  • Bortezomib Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 19, 2018
Primary completion
Feb 27, 2023
Completion
Feb 27, 2024
Last update posted
Mar 17, 2025

2018 – 2024

United States locations

U.S. sites
12
U.S. states
11
U.S. cities
12
Facility City State ZIP Site status
GSK Investigational Site Birmingham Alabama 35294
GSK Investigational Site Goodyear Arizona 85338
GSK Investigational Site Atlanta Georgia 30322-4200
GSK Investigational Site Indianapolis Indiana 46202
GSK Investigational Site Lansing Michigan 48910
GSK Investigational Site St Louis Missouri 63110
GSK Investigational Site Grand Island Nebraska 68803
GSK Investigational Site Hackensack New Jersey 07601
GSK Investigational Site New York New York 10022
GSK Investigational Site The Bronx New York 10467
GSK Investigational Site Greer South Carolina 29650
GSK Investigational Site Dallas Texas 75251

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03544281, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 17, 2025 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03544281 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →