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Completed Phase 3 Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Adults at Increased Risk for Pneumococcal Disease (V114-017/PNEU-DAY)

ClinicalTrials.gov ID: NCT03547167

Public ClinicalTrials.gov record NCT03547167. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 9:44 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multicenter, Randomized, Double-blind, Active Comparator-controlled Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by Administration of PNEUMOVAX™23 Six Months Later in Immunocompetent Adults Between 18 and 49 Years of Age at Increased Risk for Pneumococcal Disease (PNEU - DAY)

Study identification

NCT ID
NCT03547167
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
1,515 participants

Conditions and interventions

Interventions

  • V114 Biological
  • Prevnar 13™ Biological
  • PNEUMOVAX™23 Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 49 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 15, 2018
Primary completion
Jan 19, 2020
Completion
Jan 19, 2020
Last update posted
Jan 14, 2021

2018 – 2020

United States locations

U.S. sites
38
U.S. states
21
U.S. cities
37
Facility City State ZIP Site status
Chinle Comprehensive Health Care Facility ( Site 0001) Chinle Arizona 86503
Fort Defiance Center for American Indian Health ( Site 0002) Fort Defiance Arizona 86504
Pulmonary Associates, PA ( Site 0043) Glendale Arizona 85306
Central Phoenix Medical Clinic, LLC ( Site 0031) Phoenix Arizona 85020
Whiteriver Center for American Indian Health ( Site 0005) Whiteriver Arizona 85941
Inland Empire Clinical Trials, LLC ( Site 0052) Rialto California 92377
Top Medical Research, Inc ( Site 0033) Cutler Bay Florida 33189
Indago Research & Health Center, Inc ( Site 0054) Hialeah Florida 33012
Renstar Medical Research ( Site 0008) Ocala Florida 34471
Triple O Research Institute, P.A. ( Site 0026) West Palm Beach Florida 33407
Emory University School of Medicine at Grady Hospital ( Site 0027) Atlanta Georgia 30303
Kootenai Health ( Site 0042) Coeur d'Alene Idaho 83814
Evanston Premier Healthcare & Research, LLC. ( Site 0012) Evanston Illinois 60201
Pharmakon Inc ( Site 0049) Evergreen Park Illinois 60805
Reid Physician Associates ( Site 0055) Richmond Indiana 47374
The Center for Pharmaceutical Research PC ( Site 0050) Kansas City Missouri 64114
Clinical Research Consortium ( Site 0053) Las Vegas Nevada 89119
Internal Medicine Associates [Bridgeton, NJ] ( Site 0015) Bridgeton New Jersey 08302
Gallup Center for American Indian Health ( Site 0003) Gallup New Mexico 87301
Shiprock Center for American Indian Health ( Site 0004) Shiprock New Mexico 87420
Corning Center For Clinical Research ( Site 0036) Corning New York 14830
Mid Hudson Medical Research ( Site 0022) New Windsor New York 12553
Wake Research Associates, LLC ( Site 0016) Raleigh North Carolina 27612
Lehigh Valley Health Network ( Site 0040) Allentown Pennsylvania 18102
University of Pennsylvania ( Site 0030) Philadelphia Pennsylvania 19104
Mountain View Clinical Research ( Site 0007) Greer South Carolina 29651
Holston Medical Group ( Site 0025) Kingsport Tennessee 37660
AIM Trials ( Site 0060) Fort Worth Texas 76104
University of Texas Medical Branch at Galveston ( Site 0034) Galveston Texas 77555-1115
Private Practice Leadership, LLC ( Site 0051) Houston Texas 77094
Texas Center For Drug Development ( Site 0041) Houston Texas 77801
Texas Institute Of Cardiology ( Site 0048) McKinney Texas 75071
Village Health Partners ( Site 0006) Plano Texas 75024
Copperview Medical Center ( Site 0038) South Jordan Utah 84095
Timber Lane Allergy & Asthma Research, LLC ( Site 0044) South Burlington Vermont 05403
Pulmonary & Sleep Research ( Site 0046) Spokane Valley Washington 99216
Gundersen Health System ( Site 0021) La Crosse Wisconsin 54601
Marshfield Clinic ( Site 0013) Marshfield Wisconsin 54449

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03547167, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 14, 2021 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03547167 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →