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Completed Phase 3 Interventional Results available

Research Study Investigating How Well Semaglutide Works in People With Type 2 Diabetes Suffering From Overweight or Obesity

ClinicalTrials.gov ID: NCT03552757

Public ClinicalTrials.gov record NCT03552757. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 25, 2026, 12:53 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Effect and Safety of Semaglutide 2.4 mg Once-weekly in Subjects With Overweight or Obesity and Type 2 Diabetes

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will look at the change in the participant's body weight from the start to the end of the study. This is to compare the effect on body weight in people taking semaglutide (a new medicine) and people taking "dummy" medicine. In addition to taking the study medicine, the participant will have talks with study staff about healthy food choices, how to be more physically active and what else the participant can do to lose weight. Overweight and obesity is associated with an increased risk of type 2 diabetes. Therefore, weight loss has shown to have a beneficial impact on the blood sugar levels. The participant will either get semaglutide or "dummy" medicine - which treatment the participant get is decided by chance. The participant will need to take 2 injections at the same time once a week. The study medicine is injected with a thin needle in a skin fold in the stomach, thigh or upper arm. The study will last for about 1.5 years

Study identification

NCT ID
NCT03552757
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novo Nordisk A/S
Industry
Enrollment
1,210 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 3, 2018
Primary completion
Mar 23, 2020
Completion
Apr 30, 2020
Last update posted
Nov 8, 2021

2018 – 2020

United States locations

U.S. sites
50
U.S. states
20
U.S. cities
45
Facility City State ZIP Site status
Novo Nordisk Investigational Site Buena Park California 90620 —
Novo Nordisk Investigational Site Concord California 94520 —
Novo Nordisk Investigational Site Fresno California 93720 —
Novo Nordisk Investigational Site Lomita California 90717 —
Novo Nordisk Investigational Site Los Angeles California 90057 —
Novo Nordisk Investigational Site Mission Hills California 91345 —
Novo Nordisk Investigational Site Spring Valley California 91978 —
Novo Nordisk Investigational Site Tarzana California 91356-3551 —
Novo Nordisk Investigational Site Golden Colorado 80401 —
Novo Nordisk Investigational Site Clearwater Florida 33765 —
Novo Nordisk Investigational Site Jacksonville Florida 32205 —
Novo Nordisk Investigational Site Jacksonville Florida 32216 —
Novo Nordisk Investigational Site Kissimmee Florida 34744 —
Novo Nordisk Investigational Site St. Petersburg Florida 33709 —
Novo Nordisk Investigational Site Tampa Florida 33606 —
Novo Nordisk Investigational Site Alpharetta Georgia 30022 —
Novo Nordisk Investigational Site Atlanta Georgia 30318 —
Novo Nordisk Investigational Site Roswell Georgia 30076 —
Novo Nordisk Investigational Site Chicago Illinois 60607 —
Novo Nordisk Investigational Site Chicago Illinois 60611 —
Novo Nordisk Investigational Site Springfield Illinois 62711 —
Novo Nordisk Investigational Site West Des Moines Iowa 50265 —
Novo Nordisk Investigational Site Topeka Kansas 66606 —
Novo Nordisk Investigational Site Lexington Kentucky 40503 —
Novo Nordisk Investigational Site Louisville Kentucky 40213 —
Novo Nordisk Investigational Site Minneapolis Minnesota 55416 —
Novo Nordisk Investigational Site Olive Branch Mississippi 38654-3573 —
Novo Nordisk Investigational Site Butte Montana 59701 —
Novo Nordisk Investigational Site Lawrenceville New Jersey 08648 —
Novo Nordisk Investigational Site Chapel Hill North Carolina 27514 —
Novo Nordisk Investigational Site Greensboro North Carolina 27408 —
Novo Nordisk Investigational Site Greenville North Carolina 27834 —
Novo Nordisk Investigational Site Hickory North Carolina 28601 —
Novo Nordisk Investigational Site Salisbury North Carolina 28144 —
Novo Nordisk Investigational Site Wilmington North Carolina 28401 —
Novo Nordisk Investigational Site Wadsworth Ohio 44281 —
Novo Nordisk Investigational Site Anderson South Carolina 29621 —
Novo Nordisk Investigational Site Mt. Pleasant South Carolina 29464 —
Novo Nordisk Investigational Site Bristol Tennessee 37620 —
Novo Nordisk Investigational Site Nashville Tennessee 37212 —
Novo Nordisk Investigational Site Austin Texas 78749 —
Novo Nordisk Investigational Site Dallas Texas 75230 —
Novo Nordisk Investigational Site Dallas Texas 75231 —
Novo Nordisk Investigational Site Dallas Texas 75251 —
Novo Nordisk Investigational Site Dallas Texas 75390-9302 —
Novo Nordisk Investigational Site Houston Texas 77079 —
Novo Nordisk Investigational Site Shavano Park Texas 78231 —
Novo Nordisk Investigational Site St. George Utah 84790 —
Novo Nordisk Investigational Site Winchester Virginia 22601 —
Novo Nordisk Investigational Site Olympia Washington 98502 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 97 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03552757, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 8, 2021 · Synced Sep 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03552757 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →