Research Study Investigating How Well Semaglutide Works in People With Type 2 Diabetes Suffering From Overweight or Obesity
Public ClinicalTrials.gov record NCT03552757. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Effect and Safety of Semaglutide 2.4 mg Once-weekly in Subjects With Overweight or Obesity and Type 2 Diabetes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will look at the change in the participant's body weight from the start to the end of the study. This is to compare the effect on body weight in people taking semaglutide (a new medicine) and people taking "dummy" medicine. In addition to taking the study medicine, the participant will have talks with study staff about healthy food choices, how to be more physically active and what else the participant can do to lose weight. Overweight and obesity is associated with an increased risk of type 2 diabetes. Therefore, weight loss has shown to have a beneficial impact on the blood sugar levels. The participant will either get semaglutide or "dummy" medicine - which treatment the participant get is decided by chance. The participant will need to take 2 injections at the same time once a week. The study medicine is injected with a thin needle in a skin fold in the stomach, thigh or upper arm. The study will last for about 1.5 years
Study identification
- NCT ID
- NCT03552757
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,210 participants
Conditions and interventions
Conditions
Interventions
- Semaglutide 1.0 mg Drug
- Semaglutide 2.4 mg Drug
- Placebo I (Semaglutide) Drug
- Placebo II (Semaglutide) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 3, 2018
- Primary completion
- Mar 23, 2020
- Completion
- Apr 30, 2020
- Last update posted
- Nov 8, 2021
2018 – 2020
United States locations
- U.S. sites
- 50
- U.S. states
- 20
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Novo Nordisk Investigational Site | Buena Park | California | 90620 | — |
| Novo Nordisk Investigational Site | Concord | California | 94520 | — |
| Novo Nordisk Investigational Site | Fresno | California | 93720 | — |
| Novo Nordisk Investigational Site | Lomita | California | 90717 | — |
| Novo Nordisk Investigational Site | Los Angeles | California | 90057 | — |
| Novo Nordisk Investigational Site | Mission Hills | California | 91345 | — |
| Novo Nordisk Investigational Site | Spring Valley | California | 91978 | — |
| Novo Nordisk Investigational Site | Tarzana | California | 91356-3551 | — |
| Novo Nordisk Investigational Site | Golden | Colorado | 80401 | — |
| Novo Nordisk Investigational Site | Clearwater | Florida | 33765 | — |
| Novo Nordisk Investigational Site | Jacksonville | Florida | 32205 | — |
| Novo Nordisk Investigational Site | Jacksonville | Florida | 32216 | — |
| Novo Nordisk Investigational Site | Kissimmee | Florida | 34744 | — |
| Novo Nordisk Investigational Site | St. Petersburg | Florida | 33709 | — |
| Novo Nordisk Investigational Site | Tampa | Florida | 33606 | — |
| Novo Nordisk Investigational Site | Alpharetta | Georgia | 30022 | — |
| Novo Nordisk Investigational Site | Atlanta | Georgia | 30318 | — |
| Novo Nordisk Investigational Site | Roswell | Georgia | 30076 | — |
| Novo Nordisk Investigational Site | Chicago | Illinois | 60607 | — |
| Novo Nordisk Investigational Site | Chicago | Illinois | 60611 | — |
| Novo Nordisk Investigational Site | Springfield | Illinois | 62711 | — |
| Novo Nordisk Investigational Site | West Des Moines | Iowa | 50265 | — |
| Novo Nordisk Investigational Site | Topeka | Kansas | 66606 | — |
| Novo Nordisk Investigational Site | Lexington | Kentucky | 40503 | — |
| Novo Nordisk Investigational Site | Louisville | Kentucky | 40213 | — |
| Novo Nordisk Investigational Site | Minneapolis | Minnesota | 55416 | — |
| Novo Nordisk Investigational Site | Olive Branch | Mississippi | 38654-3573 | — |
| Novo Nordisk Investigational Site | Butte | Montana | 59701 | — |
| Novo Nordisk Investigational Site | Lawrenceville | New Jersey | 08648 | — |
| Novo Nordisk Investigational Site | Chapel Hill | North Carolina | 27514 | — |
| Novo Nordisk Investigational Site | Greensboro | North Carolina | 27408 | — |
| Novo Nordisk Investigational Site | Greenville | North Carolina | 27834 | — |
| Novo Nordisk Investigational Site | Hickory | North Carolina | 28601 | — |
| Novo Nordisk Investigational Site | Salisbury | North Carolina | 28144 | — |
| Novo Nordisk Investigational Site | Wilmington | North Carolina | 28401 | — |
| Novo Nordisk Investigational Site | Wadsworth | Ohio | 44281 | — |
| Novo Nordisk Investigational Site | Anderson | South Carolina | 29621 | — |
| Novo Nordisk Investigational Site | Mt. Pleasant | South Carolina | 29464 | — |
| Novo Nordisk Investigational Site | Bristol | Tennessee | 37620 | — |
| Novo Nordisk Investigational Site | Nashville | Tennessee | 37212 | — |
| Novo Nordisk Investigational Site | Austin | Texas | 78749 | — |
| Novo Nordisk Investigational Site | Dallas | Texas | 75230 | — |
| Novo Nordisk Investigational Site | Dallas | Texas | 75231 | — |
| Novo Nordisk Investigational Site | Dallas | Texas | 75251 | — |
| Novo Nordisk Investigational Site | Dallas | Texas | 75390-9302 | — |
| Novo Nordisk Investigational Site | Houston | Texas | 77079 | — |
| Novo Nordisk Investigational Site | Shavano Park | Texas | 78231 | — |
| Novo Nordisk Investigational Site | St. George | Utah | 84790 | — |
| Novo Nordisk Investigational Site | Winchester | Virginia | 22601 | — |
| Novo Nordisk Investigational Site | Olympia | Washington | 98502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 97 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03552757, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 8, 2021 · Synced Sep 25, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03552757 live on ClinicalTrials.gov.