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Completed Phase 1 Interventional

A Study of NKTR-358 (LY3471851) in Participants With Systemic Lupus Erythematosus (SLE)

ClinicalTrials.gov ID: NCT03556007

Public ClinicalTrials.gov record NCT03556007. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 12:23 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Double-blind, Randomized, Placebo-controlled, Ascending Multiple-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous NKTR-358 in Patients With Systemic Lupus Erythematosus

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main purpose of this study is to evaluate the safety and tolerability of a study drug known as LY3471851 in participants with SLE. The study will last about 79 days for each participant.

Study identification

NCT ID
NCT03556007
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Nektar Therapeutics
Industry
Enrollment
48 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 17, 2018
Primary completion
Aug 28, 2019
Completion
Aug 28, 2019
Last update posted
Nov 17, 2023

2018 – 2019

United States locations

U.S. sites
14
U.S. states
9
U.S. cities
14
Facility City State ZIP Site status
Investigator Site - Anniston Anniston Alabama 36207
Investigator Site - La Jolla La Jolla California 92037
Investigator Site - Clearwater Clearwater Florida 33765
Investigator Site - Orlando Orlando Florida 32806
Investigator Site-Tampa Tampa Florida 33603
Investigator Site - Great Neck Great Neck New York 11021
Investigator Site- Wilmington Wilmington North Carolina 28401
Investigator Site - Middleburg Heights Middleburg Heights Ohio 44130
Investigator Site - Duncansville Duncansville Pennsylvania 16635
Investigator Site - Jackson Jackson Tennessee 38305
Investigator Site - Memphis Memphis Tennessee 38119
Investigator Site - Austin Austin Texas 78745
Investigator Site - Dallas Dallas Texas 75231
Investigator Site - Mesquite Mesquite Texas 75150

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03556007, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 17, 2023 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03556007 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →