Study to Evaluate Efficacy and Safety of Benralizumab in Reducing Oral Corticosteroid Use in Adult Patients With Severe Asthma
Public ClinicalTrials.gov record NCT03557307. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
PONENTE: A Multicenter, Open-label, Phase 3b Efficacy and Safety Study of Benralizumab 30 mg Administered Subcutaneously to Reduce Oral Corticosteroid Use in Adult Patients With Severe Eosinophilic Asthma on High Dose Inhaled Corticosteroid Plus Long-acting β2 Agonist and Chronic Oral Corticosteroid Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a study designed to evaluate efficacy and safety of Benralizumab in reducing the Oral Corticosteroid (OCS) use in adult patients with severe asthma who are receiving OCS with or without additional asthma controller medications.
Study identification
- NCT ID
- NCT03557307
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 598 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 130 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 1, 2018 (Actual)
- Primary completion
- Apr 16, 2021 (Actual)
- Completion
- Mar 24, 2022 (Actual)
- Last update posted
- Jun 6, 2023
2018 – 2022
United States locations
- U.S. sites
- 23
- U.S. states
- 15
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Flagstaff | Arizona | 86001 | — |
| Research Site | Los Angeles | California | 90025 | — |
| Research Site | Aurora | Colorado | 80045 | — |
| Research Site | Newark | Delaware | 19713 | — |
| Research Site | Tampa | Florida | 33607 | — |
| Research Site | Winter Park | Florida | 32789-4681 | — |
| Research Site | Albany | Georgia | 31707 | — |
| Research Site | Atlanta | Georgia | 30322 | — |
| Research Site | Savannah | Georgia | 31405 | — |
| Research Site | Normal | Illinois | 61761 | — |
| Research Site | Georgetown | Kentucky | 40324 | — |
| Research Site | Lakeside Park | Kentucky | 41017 | — |
| Research Site | Ann Arbor | Michigan | 48109 | — |
| Research Site | Minneapolis | Minnesota | 55402 | — |
| Research Site | Saint Paul | Minnesota | 55101 | — |
| Research Site | St Louis | Missouri | 63156 | — |
| Research Site | New York | New York | 10016 | — |
| Research Site | Chapel Hill | North Carolina | 27599 | — |
| Research Site | Greenville | North Carolina | 27834 | — |
| Research Site | Wilmington | North Carolina | 28401 | — |
| Research Site | Winston-Salem | North Carolina | 27104 | — |
| Research Site | DuBois | Pennsylvania | 15801 | — |
| Research Site | North Charleston | South Carolina | 29406 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 121 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03557307, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 6, 2023 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03557307 live on ClinicalTrials.gov.