A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication
Public ClinicalTrials.gov record NCT03557931. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Randomized, Double-Blind, Placebo-Controlled, Parallel-group Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication
Study identification
- NCT ID
- NCT03557931
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Astellas Pharma Global Development, Inc.
- Industry
- Enrollment
- 233 participants
Conditions and interventions
Conditions
Interventions
- ASP4345 Drug
- aripiprazole Drug
- brexpiprazole Drug
- lurasidone Drug
- olanzapine Drug
- paliperidone Drug
- placebo Drug
- quetiapine Drug
- risperidone Drug
- ziprasidone Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 12, 2018
- Primary completion
- Oct 20, 2019
- Completion
- Oct 20, 2019
- Last update posted
- Nov 11, 2024
2018 – 2019
United States locations
- U.S. sites
- 27
- U.S. states
- 10
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| CNS Research Science, Inc. | Cerritos | California | 90703 | — |
| Collaborative Neuroscience Network, LLC | Garden Grove | California | 92845 | — |
| Synergy East | Lemon Grove | California | 91945 | — |
| Pacific Research Partners, LLC | Oakland | California | 94607 | — |
| California Neuropsychopharmacology Clinical Research Institute-LA, LLC | Pico Rivera | California | 90660 | — |
| California Neuropsychopharmacology Clinical Research Institute, LLC (CNRI-San Diego) | San Diego | California | 92102 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Sharp Mesa Vista Hospital | San Diego | California | 92123 | — |
| Collaborative Neuroscience Network, LLC | Torrance | California | 90502 | — |
| Radiant Research, Inc. | Atlanta | Georgia | 30328 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| Alam Medical Research Inc. | Chicago | Illinois | 60612 | — |
| Uptown Research Institute | Chicago | Illinois | 60640 | — |
| Michigan Clinical Research Institute PC | Ann Arbor | Michigan | 48105 | — |
| Cherry Street Services, Inc. | Grand Rapids | Michigan | 49503 | — |
| Arch Clinical Trials, LLC | St Louis | Missouri | 63118 | — |
| Hassman Research Institute | Berlin | New Jersey | 08009 | — |
| Albuquerque Neuroscience Inc. | Albuquerque | New Mexico | 87109 | — |
| SPRI Clinical Trials, LLC | Brooklyn | New York | 11235 | — |
| CNS Research Science, Inc. | Jamaica | New York | 11432 | — |
| New York State Psychiatric Institute | New York | New York | 10032 | — |
| Manhattan Psychiatric Center's 125th Street Clinic | New York | New York | 10035 | — |
| Finger Lakes Clinical Research | Rochester | New York | 14618 | — |
| Midwest Clinical Research Center | Dayton | Ohio | 45417 | — |
| Community Clinical Research, Inc. | Austin | Texas | 78754 | — |
| InSite Clinical Research, LLC | DeSoto | Texas | 75115 | — |
| Pillar Clinical Research, LLC | Richardson | Texas | 75080 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03557931, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 11, 2024 · Synced May 14, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03557931 live on ClinicalTrials.gov.