A Study to Explore the Efficacy of JNJ-67953964 in the Treatment of Depression
Public ClinicalTrials.gov record NCT03559192. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a Randomized, Double-blind, Placebo-Controlled, Parallel-Group, Multi-center Study Investigating the Efficacy, Safety, Tolerability and Pharmacokinetics of JNJ-67953964 in Subjects With Major Depressive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy of JNJ-67953964 compared to placebo when administered as adjunctive treatment in participants with Major Depressive Disorder (MDD) partially responsive to selective serotonin reuptake inhibitor/ serotonin-norepinephrine reuptake inhibitor (SSRI/SNRI) treatment in terms of reduction of symptoms of depression, as assessed by the change from baseline on the Montgomery Asberg Depression Rating Scale (MADRS) in non-responders during the placebo lead-in period.
Study identification
- NCT ID
- NCT03559192
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 181 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 16, 2018 (Actual)
- Primary completion
- May 6, 2020 (Actual)
- Completion
- May 6, 2020 (Actual)
- Last update posted
- Apr 29, 2025
2018 – 2020
United States locations
- U.S. sites
- 28
- U.S. states
- 16
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Noble Clinical Research | Tucson | Arizona | 85704 | — |
| Preferred Research Partners | Little Rock | Arkansas | 72211 | — |
| Behavioral Research Specialists LLC | Glendale | California | 91206 | — |
| NRC Research Institute | Orange | California | 92868 | — |
| Artemis Institute for Clinical Research | Riverside | California | 92503 | — |
| Artemis Institute for Clinical Research | San Marcos | California | 92078 | — |
| Pacific Clinical Research Medical Group | Upland | California | 91786 | — |
| Innova Clinical Trials | Miami | Florida | 33133 | — |
| Galiz Research | Miami Springs | Florida | 33166 | — |
| APG Research LLC | Orlando | Florida | 32803 | — |
| Olympian Clinical Research | Tampa | Florida | 33614 | — |
| Meridien Research | Tampa | Florida | 33634 | — |
| Atlanta Behavioral Research, LLC | Atlanta | Georgia | 30338 | — |
| Chicago Research Center | Chicago | Illinois | 60634 | — |
| Psychiatric Medicine Associates LLC | Skokie | Illinois | 60076 | — |
| Lake Charles Clinical Trials | Lake Charles | Louisiana | 70629 | — |
| Princeton Medical Institute | Princeton | New Jersey | 08540 | — |
| Integrative Clinical Trials LLC | Brooklyn | New York | 11229 | — |
| Richmond Behavioural Associates | Staten Island | New York | 10312 | — |
| Clinical Trials of America | Hickory | North Carolina | 28601 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Midwest Clinical Research Center | Dayton | Ohio | 45417 | — |
| IPS Research Company | Oklahoma City | Oklahoma | 73106 | — |
| Paradigm Research Professionals, LLC | Oklahoma City | Oklahoma | 73118 | — |
| Lehigh Center for Clinical Research | Allentown | Pennsylvania | 18104 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Clinical NeuroScience Solutions Inc | Memphis | Tennessee | 38119 | — |
| Advanced Clinical Research | West Jordan | Utah | 84088 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 25 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03559192, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 29, 2025 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03559192 live on ClinicalTrials.gov.