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Terminated Phase 3 Interventional Results available

Study of Rapastinel as Monotherapy in Patients With MDD

ClinicalTrials.gov ID: NCT03560518

Public ClinicalTrials.gov record NCT03560518. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 4:18 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled, Multicenter Study of Rapastinel as Monotherapy in Patients With Major Depressive Disorder

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The study will evaluate the efficacy, safety, and tolerability of 450 milligrams (mg) and 900 milligrams (mg) of Rapastinel, compared to placebo in participants with major depressive disorder (MDD).

Study identification

NCT ID
NCT03560518
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Enrollment
439 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 14, 2018
Primary completion
Jul 7, 2019
Completion
Jul 7, 2019
Last update posted
Aug 31, 2020

2018 – 2019

United States locations

U.S. sites
40
U.S. states
19
U.S. cities
37
Facility City State ZIP Site status
Alea Research Phoenix Arizona 85012
Woodland International Research Group Little Rock Arkansas 72211
California Pharmaceutical Research Institute, Inc. Anaheim California 92804
Collaborative Neuroscience Network Garden Grove California 92845
Synergy Research San Diego National City California 91950
Excell Research Inc. Oceanside California 92056
NRC Research Institute Orange California 92868
Artemis Institute for Clinical Research San Diego California 92103
California Neuroscience Research Medical Group,Inc. Sherman Oaks California 91403
Viking Clinical Research Ltd. Temecula California 92591
Pacific Clinical Research Medical Group Upland California 91786
Research Centers of America, LLC Hollywood Florida 33024
Clinical Neuroscience Solutions, Inc. Jacksonville Florida 32256
Innovative Clinical Research, Inc. Lauderhill Florida 33319
Innova Clinical Trials Miami Florida 33133
Atlanta Center for Medical Research Atlanta Georgia 30331
Institute for Advanced Medical Research Atlanta Georgia 30341
iResearch Atlanta, LLC Decatur Georgia 30030
Iris Research, Inc. Smyrna Georgia 30082
Capstone Clinical Research Libertyville Illinois 60048
Pharmasite Research, Inc. Baltimore Maryland 21208
CBH Health, LLC Gaithersburg Maryland 20877
Boston Clinical Trials Boston Massachusetts 02131
Adams Clinical Watertown Massachusetts 02472
Precise Research Centers Flowood Mississippi 39232
Millennium Psychiatric Associates, LLC Creve Coeur Missouri 63141
Altea Research Institute Las Vegas Nevada 89102
Hassman Research Institute Berlin New Jersey 08009
Bioscience Research LLC Mount Kisco New York 10549
Icahn School of Medicine at Mount Sinai New York New York 10028
Eastside Comprehensive Medical Center, LLC New York New York 10128
The Medical Research Network, LLC New York New York 10128
Finger Lakes Clinical Research Rochester New York 14618
New Hope Clinical Research Inc. Charlotte North Carolina 28211
Midwest Clinical Research Center Dayton Ohio 45417
IPS Research Company Oklahoma City Oklahoma 73103
Suburban Research Associates Media Pennsylvania 19063
Keystone Clinical Studies, LLC Norristown Pennsylvania 19403
Donald J. Garcia, Jr., MD, PA Austin Texas 78737
Northwest Clinical Research Center Bellevue Washington 98007

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03560518, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 31, 2020 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03560518 live on ClinicalTrials.gov.

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