Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS)
Public ClinicalTrials.gov record NCT03560986. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Placebo-controlled Efficacy and Safety Trial of Intravenous Neridronic Acid in Subjects With Complex Regional Pain Syndrome (CRPS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The aim of this trial was to investigate the efficacy and safety of intravenous neridronic acid in subjects with Complex Regional Pain Syndrome (CRPS). The trial consisted of an Enrollment Period lasting up to 60 days, Treatment Period A consisting of 4 infusions (neridronic acid 100 mg or placebo) over 10 days, and a Follow-up Period 1 until Week 26. At Week 26, participants meeting the pre-specified criteria entered the open-label Treatment Period B with 4 additional infusions (neridronic acid) over 10 days and follow-up visits until Week 52. Participants not meeting the pre-specified criteria to continue into Treatment Period B continued in Follow-up Period 2 until Week 52.
Study identification
- NCT ID
- NCT03560986
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 267 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2018 (Actual)
- Primary completion
- Aug 1, 2019 (Actual)
- Completion
- Aug 1, 2019 (Actual)
- Last update posted
- Aug 5, 2020
2018 – 2019
United States locations
- U.S. sites
- 41
- U.S. states
- 20
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| US446 - Clinical Trial Connection | Cottonwood | Arizona | 86326 | — |
| US453 - Physicians Research Group II, LLC | Tempe | Arizona | 85284 | — |
| US428 - Quality of Life Medical and Research Center LLC | Tucson | Arizona | 85712 | — |
| US422 - Woodland International Research Group | Little Rock | Arkansas | 72211 | — |
| US454 - Alliance Research Institute | Canoga Park | California | 91304 | — |
| US415 - Clearview Medical Research LLC | Canyon Country | California | 91351 | — |
| US410 - Alliance Research Centers | Laguna Hills | California | 92653 | — |
| US432 - Torrance Clinical Research Institute Inc. | Lomita | California | 90717 | — |
| Us414 - Alexander Ford Md | Los Angeles | California | 90035 | — |
| US441 - Samaritan Center for Medical Research | Los Gatos | California | 95032 | — |
| US406 - CI Trials | Santa Ana | California | 92705 | — |
| US411 - Syrentis Clinical Research | Santa Ana | California | 92705 | — |
| US420 - Mountain View Clinical Research, INC | Denver | Colorado | 80209 | — |
| US447 - ASCLEPES Research Centers | Brooksville | Florida | 34613 | — |
| US457 - Florida Spine Institute | Clearwater | Florida | 33765 | — |
| US430 - South Lake Pain Institute | Clermont | Florida | 34711 | — |
| US434 - Finlay Medical Research | Miami | Florida | 33126 | — |
| US407 - Oceane 7 Medical and Research Center, Inc. | Miami | Florida | 33144 | — |
| US436 - Cordova Research Institute | Miami | Florida | 33155 | — |
| US417 - Tampa Pain Relief Center | Tampa | Florida | 33603 | — |
| US403 - Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| US404 - Infinite Clinical Trials | Riverdale | Georgia | 30274 | — |
| US424 - Georgia Neurology and Sleep Medicine Assoc. | Suwanee | Georgia | 30024 | — |
| US431 - Injury Care Research, LLC | Boise | Idaho | 83713 | — |
| US437 - Great Lakes Clinical Trials LLC | Chicago | Illinois | 60640 | — |
| US435 - Centex Studies Inc | Lake Charles | Louisiana | 70601 | — |
| US448 - The Center for Rheumatology and Bone Research | Wheaton | Maryland | 20902 | — |
| US450 - SRI International | Plymouth | Michigan | 48170 | — |
| US449 - Michigan Pain Consultants | Wyoming | Michigan | 49503 | — |
| US433 - Creighton University - Osteoporosis Research Center | Omaha | Nebraska | 68122 | — |
| US419 - Manhattan Behavioral Medicine | New York | New York | 10036 | — |
| US440 - OnSite Clinical Solutions LLC | Charlotte | North Carolina | 28210 | — |
| US405 - OnSite Clinical Solutions LLC | Hickory | North Carolina | 28601 | — |
| US416 - Medical Research International | Oklahoma City | Oklahoma | 73109 | — |
| US429 - Lehigh Valley Health | Allentown | Pennsylvania | 18103 | — |
| US438 - Abington Neurological Associates, LTD. | Willow Grove | Pennsylvania | 19090 | — |
| US425 - PCPMG Clinical Research Unit LLC | Greenville | South Carolina | 29601 | — |
| US423 - Biopharma Informatic Inc. Research Center | Houston | Texas | 77043 | — |
| US443 - Centex Studies Inc | Houston | Texas | 77058 | — |
| US421 - Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
| US445 - Exemplar Research Inc | Morgantown | West Virginia | 26505 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03560986, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 5, 2020 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03560986 live on ClinicalTrials.gov.