ClinicalTrials.gov record
Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)
ClinicalTrials.gov ID: NCT03561883
Public ClinicalTrials.gov record NCT03561883. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Trial of Oral IW-3718 Administered to Patients With Gastroesophageal Reflux Disease While Receiving Proton Pump Inhibitors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to evaluate the safety and efficacy of IW-3718 administered to patients with GERD who continue to have persistent symptoms, such as heartburn and regurgitation, while receiving once-daily (QD), standard dose PPIs.
Study identification
- NCT ID
- NCT03561883
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 609 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 5, 2018
- Primary completion
- Jul 27, 2020
- Completion
- Nov 5, 2020
- Last update posted
- Aug 17, 2021
2018 – 2020
United States locations
- U.S. sites
- 98
- U.S. states
- 31
- U.S. cities
- 84
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Digestive Health Specialists of The Southeast | Dothan | Alabama | 36305 | — |
| Holland Center for Family Health | Peoria | Arizona | 85381 | — |
| Hope Research Institute LLC | Peoria | Arizona | 85381 | — |
| Atria Clinical Research | Little Rock | Arkansas | 72209 | — |
| Preferred Research Partners | Little Rock | Arkansas | 72211 | — |
| Hope Clinical Research, LLC | Canoga Park | California | 91303 | — |
| Om Research LLC | Lancaster | California | 93534 | — |
| Torrance Clinical Research | Lomita | California | 90717 | — |
| United Gastroenterologists | Murrieta | California | 92563 | — |
| Clinical Applications Laboratories Inc | San Diego | California | 92103 | — |
| Care Access Research, San Pablo | San Pablo | California | 94806 | — |
| Paragon Rx Clinical, Inc. - Santa Ana | Santa Ana | California | 92703 | — |
| Medical Research Center of Connecticut LLC | Hamden | Connecticut | 06518 | — |
| Yale School of Medicine | New Haven | Connecticut | 06510 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| Optimus U Corp | Coral Gables | Florida | 33134 | — |
| Nature Coast Clinical Research LLC - ERN-PPDS | Inverness | Florida | 34452 | — |
| Jacksonville Center For Clinical Research | Jacksonville | Florida | 32207 | — |
| Precision Clinical Research, LLC | Lauderdale Lakes | Florida | 33319 | — |
| Suncoast Research Group LLC - ERN-PPDS | Miami | Florida | 33135 | — |
| Applemed Research Inc | Miami | Florida | 33155 | — |
| Gutierrez Medical Center | Orlando | Florida | 32807 | — |
| Columbus Regional Research Institute at Talbotton | Columbus | Georgia | 31904 | — |
| Consultative Gastroenterology | Decatur | Georgia | 30034 | — |
| Atlanta Center For Clinical Research | Roswell | Georgia | 30075 | — |
| Clinical Research Atlanta - ERN-PPDS | Stockbridge | Georgia | 30281 | — |
| IL Gastroenterology Group | Gurnee | Illinois | 60041 | — |
| Edward Hines Jr VA Hospital - NAVREF | Hines | Illinois | 60141 | — |
| Aquiant Research | New Albany | Indiana | 47150 | — |
| Kansas Medical Clinic | Topeka | Kansas | 66606 | — |
| Heartland Research Associates LLC | Wichita | Kansas | 67207 | — |
| Gastroenterology Associates LLC | Baton Rouge | Louisiana | 70809 | — |
| Texas Digestive Disease Consultants | Baton Rouge | Louisiana | 70809 | — |
| Clinical Trials of America LA LLC | West Monroe | Louisiana | 71291 | — |
| Investigative Clinical Research | Annapolis | Maryland | 21401 | — |
| Centennial Medical Group | Elkridge | Maryland | 21075 | — |
| Commonwealth Clinical Studies LLC | Brockton | Massachusetts | 02302 | — |
| Center For Digestive Health | Troy | Michigan | 48098 | — |
| Gastroenterology Associates of West Michigan | Wyoming | Michigan | 49519 | — |
| Gastroenterology Associates of Western Michigan, PLC | Wyoming | Michigan | 49519 | — |
| Gastrointestinal Associates PA | Flowood | Mississippi | 39232 | — |
| Kansas City VA Medical Center - NAVREF | Kansas City | Missouri | 64128 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Digestive Disease Specialists | Las Vegas | Nevada | 89128 | — |
| Office of Michael Zimmerman, MD | Las Vegas | Nevada | 89128 | — |
| Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| NYScientific | Brooklyn | New York | 11235 | — |
| Long Island Gastrointestinal Research Group LLP | Great Neck | New York | 11023 | — |
| United Health Services Hospitals | Johnson City | New York | 13790 | — |
| Syracuse VA Medical Center - NAVREF | Syracuse | New York | 13210 | — |
| Advantage Clinical Trials | The Bronx | New York | 10468 | — |
| Asheville Gastroenterology Associates PA | Asheville | North Carolina | 28801 | — |
| UNC Medical Center | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Carolina Digestive Diseases | Greenville | North Carolina | 27834 | — |
| Clinical Trials of America-NC, LLC | Mount Airy | North Carolina | 27030 | — |
| PMG Research of Salisbury LLC | Salisbury | North Carolina | 28144 | — |
| Trial Management Associates LLC | Wilmington | North Carolina | 28403 | — |
| Hightop Medical Research Center | Cincinnati | Ohio | 45224 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Remington Davis Inc | Columbus | Ohio | 43214 | — |
| Dayton Gastroenterology Inc | Dayton | Ohio | 45440 | — |
| Prestige Clinical Research | Franklin | Ohio | 45005 | — |
| Central Sooner Research | Norman | Oklahoma | 73071 | — |
| The University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Lynn Health Science Institute - ERN-PPDS | Oklahoma City | Oklahoma | 73112 | — |
| Northwest Gastroenterology Clinic | Portland | Oregon | 97210 | — |
| Research Protocol Management Specialists | Pittsburgh | Pennsylvania | 15241 | — |
| Research Protocol Management Specialists | Pittsburgh | Pennsylvania | 15243 | — |
| Guthrie Research Institute | Sayre | Pennsylvania | 18840 | — |
| Omega Medical Research | Warwick | Rhode Island | 02886 | — |
| Clinical Trials of South Carolina - ClinEdge - PPDS | Charleston | South Carolina | 29406 | — |
| Pharmacorp Clinical Trials Incorporated | Charleston | South Carolina | 29412 | — |
| Gastroenterology Associates, PA | Greenville | South Carolina | 29615 | — |
| Coastal Carolina Research Center | Mt. Pleasant | South Carolina | 29464 | — |
| Clinical Trials of South Carolina | North Charleston | South Carolina | 29406 | — |
| Franklin Gastroenterology | Franklin | Tennessee | 37067 | — |
| Clinical Research Solutions PC | Jackson | Tennessee | 38305 | — |
| QUALITY Medical Research - Interspond - PPDS | Nashville | Tennessee | 37211 | — |
| Inquest Clinical Research | Baytown | Texas | 77521 | — |
| Texas Health Physicians Group | Carrollton | Texas | 75007 | — |
| Northside Gastroenterology | Cypress | Texas | 77429 | — |
| Texas Tech University Health Sciences Center | El Paso | Texas | 79905 | — |
| Kelsey Research Foundation | Houston | Texas | 77025 | — |
| Houston Endoscopy and Research Center | Houston | Texas | 77079 | — |
| Coastal Medical Group | Houston | Texas | 77089 | — |
| San Antonio Gastroenterology Associates Clinical Trials (SAGACT PLLC) | San Antonio | Texas | 78229 | — |
| Care Access Research | Salt Lake City | Utah | 84124 | — |
| University of Utah Health Sciences Center | Salt Lake City | Utah | 84132-2101 | — |
| University of Utah Hospital | Salt Lake City | Utah | 84132-2101 | — |
| Advanced Clinical Research - Gut Whisperer- ERN-PPDS | West Jordan | Utah | 84088 | — |
| Digestive and Liver Disease Specialists | Norfolk | Virginia | 23502 | — |
| The Gastroenterology Group | Reston | Virginia | 22191 | — |
| Clinical Research Partners LLC | Richmond | Virginia | 23220 | — |
| Clinical Research Partners LLC | Richmond | Virginia | 23235 | — |
| Aurora Medical Center Summit | Summit | Wisconsin | 53066 | — |
| Aurora Health Care | Waukesha | Wisconsin | 53186 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
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About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03561883, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 17, 2021 · Synced Sep 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03561883 live on ClinicalTrials.gov.