ClinicalTrials.gov record
Javelin BRCA/ATM: Avelumab Plus Talazoparib in Patients With BRCA or ATM Mutant Solid Tumors
ClinicalTrials.gov ID: NCT03565991
Public ClinicalTrials.gov record NCT03565991. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2 STUDY TO EVALUATE SAFETY AND ANTI-TUMOR ACTIVITY OF AVELUMAB IN COMBINATION WITH TALAZOPARIB IN PATIENTS WITH BRCA OR ATM MUTANT TUMORS JAVELIN BRCA/ATM
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Avelumab in combination with talazoparib will be investigated in patients with locally advanced or metastatic solid tumors with a BRCA or ATM defect.
Study identification
- NCT ID
- NCT03565991
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 202 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 18, 2018 (Actual)
- Primary completion
- Mar 28, 2022 (Actual)
- Completion
- Feb 3, 2023 (Actual)
- Last update posted
- Sep 25, 2023
2018 – 2023
United States locations
- U.S. sites
- 72
- U.S. states
- 12
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Stanford Cancer Center | Palo Alto | California | 94304 | — |
| Stanford Women's Cancer Center | Palo Alto | California | 94304 | — |
| Stanford Healthcare | Stanford | California | 94305 | — |
| Stanford University School of Medicine | Stanford | California | 94305 | — |
| Atlanta Cancer Care -Alpharetta | Alpharetta | Georgia | 30005 | — |
| Northside Hospital, Inc. - GCS/Athens | Athens | Georgia | 30606 | — |
| Northside Hospital, Inc. - GCS/Annex | Atlanta | Georgia | 30341 | — |
| Atlanta Cancer Care - Atlanta | Atlanta | Georgia | 30342 | — |
| Northside Hospital, Inc. - Central Research Department | Atlanta | Georgia | 30342 | — |
| Northside Hospital, Inc. - GCS/Northside | Atlanta | Georgia | 30342 | — |
| Northside Hospital, Inc. - GCS/Canton | Canton | Georgia | 30114 | — |
| Atlanta Cancer Care - Cumming | Cumming | Georgia | 30041 | — |
| Atlanta Cancer Care - Decatur | Decatur | Georgia | 30033 | — |
| Northside Hospital, Inc.-GCS/Stemmer | Decatur | Georgia | 30033 | — |
| Atlanta Cancer Care - Stockbridge | Jonesboro | Georgia | 30236 | — |
| Northside Hospital, Inc.-GCS/Macon | Macon | Georgia | 31217 | — |
| Northside Hospital, Inc.-GCS/Kennestone | Marietta | Georgia | 30060 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Dana Farber Cancer institute | Boston | Massachusetts | 02215 | — |
| Siteman Cancer Center - St.Peters | City of Saint Peters | Missouri | 63376 | — |
| Siteman Cancer Center - West County | Creve Coeur | Missouri | 63141 | — |
| Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Washington University Infusion Center Pharmacy | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Siteman Cancer Center - South County | St Louis | Missouri | 63129 | — |
| Siteman Cancer Center - North County | St Louis | Missouri | 63136 | — |
| Memorial Sloan Kettering Cancer Center- Monmouth | Middletown | New Jersey | 07748 | — |
| Memorial Sloan Kettering Cancer Center- Westchester | Harrison | New York | 10604 | — |
| Memorial Sloan Kettering Cancer Center - Investigational Drug Service Pharmacy | Long Island City | New York | 11101 | — |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | — |
| Laura and Isaac Perlmutter Cancer Center | New York | New York | 10016 | — |
| NY Investigational Pharmacy | New York | New York | 10016 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| NYU Langone Radiology - 32nd Street | New York | New York | 10016 | — |
| NYU Langone Radiology Ambulatory Care Center East 41st Street | New York | New York | 10017 | — |
| Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street). | New York | New York | 10021 | — |
| Rockefeller Outpatient Center | New York | New York | 10022 | — |
| Rockefeller Outpatient Pavilion (53rd Street) | New York | New York | 10022 | — |
| Evelyn H. Lauder Breast and Imaging Center | New York | New York | 10065 | — |
| Memorial Hospital | New York | New York | 10065 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| White Plains Hospital | White Plains | New York | 10601 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Stephanie Spielman Comprehensive Breast Cancer | Columbus | Ohio | 43212 | — |
| Martha Morehouse Medical Plaza | Columbus | Ohio | 43221 | — |
| OSU Gynecologic Oncology at Mill Run | Hilliard | Ohio | 43026 | — |
| Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | — |
| Hospital of the University of Pennsylvania/Penn Investigational Drug Services | Philadelphia | Pennsylvania | 19104 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Penn IDS Central | Philadelphia | Pennsylvania | 19104 | — |
| Magee-Women's Hospital Women's Cancer Center | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC Hillman Cancer Center Investigational Drug Service | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Tennessee Oncology, PLLC | Chattanooga | Tennessee | 37404 | — |
| The Sarah Cannon Research Institute | Chattanooga | Tennessee | 37404 | — |
| Tennessee Oncology, PLLC | Cleveland | Tennessee | 37311 | — |
| Tennessee Oncology, PLLC | Dickson | Tennessee | 37055 | — |
| Tennessee Oncology, PLLC | Franklin | Tennessee | 37067 | — |
| Tennessee Oncology, PLLC | Gallatin | Tennessee | 37066 | — |
| Tennessee Oncology, PLLC | Hermitage | Tennessee | 37076 | — |
| Tennessee Oncology, PLLC | Lebanon | Tennessee | 37090 | — |
| Tennessee Oncology, PLLC | Murfreesboro | Tennessee | 37129 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37203 | — |
| The Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37205 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37207 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37211 | — |
| Tennessee Oncology, PLLC | Shelbyville | Tennessee | 37160 | — |
| Tennessee Oncology, PLLC | Smyrna | Tennessee | 37167 | — |
| The University of Texas | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 28 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03565991, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 25, 2023 · Synced Oct 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03565991 live on ClinicalTrials.gov.