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Completed Phase 3 Interventional Results available

Evaluating the Effects of Tradipitant vs. Placebo in Atopic Dermatitis (EPIONE)

ClinicalTrials.gov ID: NCT03568331

Public ClinicalTrials.gov record NCT03568331. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 2:49 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled Efficacy Study of The Neurokinin-1 Receptor Antagonist VLY-686 in Patients With Atopic Dermatitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a multicenter, randomized, double-blind, placebo-controlled study to be conducted in the United States in subjects with atopic dermatitis.

Study identification

NCT ID
NCT03568331
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Vanda Pharmaceuticals
Industry
Enrollment
375 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 9, 2018 (Actual)
Primary completion
Dec 27, 2019 (Actual)
Completion
Dec 27, 2019 (Actual)
Last update posted
May 13, 2024

2018 – 2019

United States locations

U.S. sites
70
U.S. states
30
U.S. cities
63
Facility City State ZIP Site status
Vanda Investigational Site Birmingham Alabama 35224 —
Vanda Investigational Site Birmingham Alabama 35233 —
Vanda Investigational Site Tempe Arizona 85283 —
Vanda Investigational Site Encino California 91436 —
Vanda Investigational Site Fountain Valley California 92708 —
Vanda Investigational Site Fremont California 94538 —
Vanda Investigational Site Laguna Hills California 92653 —
Vanda Investigational Site Lomita California 90717 —
Vanda Investigational Site Long Beach California 90806 —
Vanda Investigational Site Los Angeles California 90017 —
Vanda Investigational Site Los Angeles California 90036 —
Vanda Investigational Site San Diego California 92122 —
Vanda Investigational Site Santa Monica California 90404 —
Vanda Investigational Site Denver Colorado 80220 —
Vanda Investigational Site Aventura Florida 33180 —
Vanda Investigational Site Clearwater Florida 33756 —
Vanda Investigational Site Fort Lauderdale Florida 33306 —
Vanda Investigational Site Hialeah Florida 33016 —
Vanda Investigational Site Miami Florida 33126 —
Vanda Investigational Site Miami Florida 33137 —
Vanda Investigational Site Miramar Florida 33027 —
Vanda Investigational Site Ormond Beach Florida 32174 —
Vanda Investigational Site South Miami Florida 33143 —
Vanda Investigational Site Tampa Florida 33613 —
Vanda Investigational Site Savannah Georgia 31406 —
Vanda Investigational Site Boise Idaho 83704 —
Vanda Investigational Site Normal Illinois 61761 —
Vanda Investigational Site Skokie Illinois 60077 —
Vanda Investigational Site Plainfield Indiana 46168 —
Vanda Investigational Site Crowley Louisiana 70526 —
Vanda Investigational Site Rockville Maryland 20850 —
Vanda Investigational Site Towson Maryland 21204 —
Vanda Investigational Site Beverly Massachusetts 01915 —
Vanda Investigational Site Brighton Massachusetts 02135 —
Vanda Investigational Site Fort Gratiot Michigan 48059 —
Vanda Investigational Site Saint Joseph Missouri 64506 —
Vanda Investigational Site St Louis Missouri 63141 —
Vanda Investigational Site Omaha Nebraska 68144 —
Vanda Investigational Site Las Vegas Nevada 89106 —
Vanda Investigational Site Las Vegas Nevada 89119 —
Vanda Investigational Site Berlin New Jersey 08009 —
Vanda Investigational Site Verona New Jersey 07044 —
Vanda Investigational Site Brooklyn New York 11201 —
Vanda Investigational Site New York New York 10003 —
Vanda Investigational Site New York New York 10022 —
Vanda Investigational Site New York New York 10075 —
Vanda Investigational Site Charlotte North Carolina 28277 —
Vanda Investigational Site High Point North Carolina 27262 —
Vanda Investigational Site Wilmington North Carolina 28405 —
Vanda Investigational Site Cincinnati Ohio 45212 —
Vanda Investigational Site Dayton Ohio 45414 —
Vanda Investigational Site Oklahoma City Oklahoma 73112 —
Vanda Investigational Site Tulsa Oklahoma 74136 —
Vanda Investigational Site Philadelphia Pennsylvania 19104 —
Vanda Investigational Site Pittsburgh Pennsylvania 15213 —
Vanda Investigational Site Johnston Rhode Island 02919 —
Vanda Investigational Site North Charleston South Carolina 29420 —
Vanda Investigational Site Spartanburg South Carolina 29301 —
Vanda Investigational Site Chattanooga Tennessee 37421 —
Vanda Investigational Site Nashville Tennessee 37211 —
Vanda Investigational Site Dallas Texas 75230 —
Vanda Investigational Site Pflugerville Texas 78660 —
Vanda Investigational Site San Antonio Texas 78213 —
Vanda Investigational Site San Antonio Texas 78218 —
Vanda Investigational Site West Jordan Utah 84088 —
Vanda Investigational Site South Burlington Vermont 05403 —
Vanda Investigational Site Newport News Virginia 23606 —
Vanda Investigational Site Norfolk Virginia 23507 —
Vanda Investigational Site Richmond Virginia 23233 —
Vanda Investigational Site Spokane Washington 99202 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03568331, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 13, 2024 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03568331 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →