ClinicalTrials.gov record
A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
ClinicalTrials.gov ID: NCT03573908
Public ClinicalTrials.gov record NCT03573908. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b, Randomized, Double-blind, Placebo-controlled, Parallel-group Trial of Linaclotide 290 μg Administered Orally for 12 Weeks Followed by a 4-week Randomized Withdrawal Period in Patients With Irritable Bowel Syndrome With Constipation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To evaluate the efficacy on abdominal symptoms (abdominal bloating, abdominal discomfort, and abdominal pain) and safety of linaclotide 290 μg administered orally to patients with IBS-C.
Study identification
- NCT ID
- NCT03573908
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 614 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 20, 2018 (Actual)
- Primary completion
- Mar 13, 2019 (Actual)
- Completion
- Apr 10, 2019 (Actual)
- Last update posted
- Dec 1, 2020
2018 – 2019
United States locations
- U.S. sites
- 79
- U.S. states
- 27
- U.S. cities
- 70
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Associates | Huntsville | Alabama | 35801 | — |
| Elite Clinical Studies | Phoenix | Arizona | 85018 | — |
| Adobe Clinical Research, LLC | Tucson | Arizona | 85712 | — |
| Arkansas Gastroenterology | North Little Rock | Arkansas | 72117 | — |
| GW Research, Inc. | Chula Vista | California | 91910 | — |
| Kindred Medical Institute for Clinical Trials, LLC | Corona | California | 92879 | — |
| Diagnamics, Inc. | Encinitas | California | 92024 | — |
| MD Studies, Inc. | Fountain Valley | California | 92708 | — |
| Paragon Rx Clinical, Inc. - Garden Grove | Garden Grove | California | 92840 | — |
| Grossmont Center For Clinical Research | La Mesa | California | 91942 | — |
| Facey Medical Foundation | Mission Hills | California | 91345 | — |
| Providence Clinical Research | North Hollywood | California | 91606 | — |
| Precision Research Institute | San Diego | California | 92114 | — |
| Paragon Rx Clinical, Inc.- Santa Ana | Santa Ana | California | 92703 | — |
| Millennium Clinical Trials | Thousand Oaks | California | 91360 | — |
| St. Joseph Heritage Healthcare | Yorba Linda | California | 92886 | — |
| Connecticut Clinical Research Institute | Bristol | Connecticut | 06010 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| Clinical Research of South Florida | Coral Gables | Florida | 33134 | — |
| Avail Clinical Research, LLC | DeLand | Florida | 32720 | — |
| Palmetto Research, LLC | Hialeah | Florida | 33016 | — |
| Nature Coast Clinical Research, LLC | Inverness | Florida | 34452 | — |
| The Chappel Group Research | Kissimmee | Florida | 34741 | — |
| Jesscan Medical Research | Miami | Florida | 33134 | — |
| Well Pharma Medical Research Corporation | Miami | Florida | 33143 | — |
| New Horizon Research Center | Miami | Florida | 33175 | — |
| San Marcus Research Clinic, Inc. | Miami Lakes | Florida | 33014 | — |
| Ocean Blue Medical Research Center, Inc. | Miami Springs | Florida | 33166 | — |
| Ormond Medical Arts Pharmaceutical Research Center | Ormond Beach | Florida | 32174 | — |
| Precision Clinical Research | Sunrise | Florida | 33351 | — |
| Meridien Research - Tampa | Tampa | Florida | 33634 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| Research Institute of Central Florida, LLC | Winter Park | Florida | 32792 | — |
| Mount Vernon Clinical Research, LLC | Sandy Springs | Georgia | 30328 | — |
| Clinical Trials Management, LLC | Metairie | Louisiana | 70006 | — |
| Delta Research Partners, LLC | Monroe | Louisiana | 71201 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Alan A. Rosen, MD, PA | Baltimore | Maryland | 21215 | — |
| Meritus Center For Clinical Research | Hagerstown | Maryland | 21742 | — |
| Boston Clinical Trials, Inc. | Boston | Massachusetts | 02131 | — |
| MedVadis Research Corporation | Watertown | Massachusetts | 02472 | — |
| Gastroenterology Associates of West Michigan | Wyoming | Michigan | 49519 | — |
| Gastrointestinal Associates PA | Flowood | Mississippi | 39232 | — |
| St. Louis Center For Clinical Research | St Louis | Missouri | 63128 | — |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59718 | — |
| Clinical Research of South Nevada | Las Vegas | Nevada | 89121 | — |
| Healthwise Medical Associates | Brooklyn | New York | 11206 | — |
| Long Island Gastrointestinal Research Group, LLP | Great Neck | New York | 11023 | — |
| Carolina Digestive Health Associates | Charlotte | North Carolina | 28210 | — |
| Carolina Digestive Health Associates | Concord | North Carolina | 28025 | — |
| Cumberland Research Associates | Fayetteville | North Carolina | 28304 | — |
| Peters Medical Research, LLC | High Point | North Carolina | 27262 | — |
| Wake Research Associates, LLC | Raleigh | North Carolina | 27612 | — |
| PMG Research of Wilmington | Wilmington | North Carolina | 28401 | — |
| Clinical Trials of America - North Carolina, LLC | Winston-Salem | North Carolina | 27103 | — |
| Lyndhurst Clinical Research | Winston-Salem | North Carolina | 27103 | — |
| PMG Research of Winston-Salem | Winston-Salem | North Carolina | 27103 | — |
| Lillestol Research | Fargo | North Dakota | 58104 | — |
| Hightop Medical Research Center | Cincinnati | Ohio | 45224 | — |
| New Horizons Clinical Research | Cincinnati | Ohio | 45242 | — |
| Remington Davis, Inc. | Columbus | Ohio | 43215 | — |
| Dayton Gastroenterology, Inc. | Dayton | Ohio | 45415 | — |
| Hometown Urgent Care and Research | Dayton | Ohio | 45424 | — |
| Great Lakes Gastroenterology Research, LLC | Mentor | Ohio | 44060 | — |
| IPS Research Company | Oklahoma City | Oklahoma | 73106 | — |
| Partners In Clinical Research | Cumberland | Rhode Island | 02864 | — |
| Mountain View Clinical Research, Inc. | Greer | South Carolina | 29651 | — |
| Meridian Clinical Research | Dakota Dunes | South Dakota | 57049 | — |
| ClinSearch, LLC | Chattanooga | Tennessee | 37421 | — |
| New Phase Research & Development | Knoxville | Tennessee | 37909 | — |
| MW Clinical Research Center | Beaumont | Texas | 77701 | — |
| Southwest Clinical Trials | Houston | Texas | 77074 | — |
| Southwest Clinical Trials | Houston | Texas | 77081 | — |
| Quality Research, Inc. | San Antonio | Texas | 78209 | — |
| Diagnostics Research Group | San Antonio | Texas | 78229 | — |
| Stone Oak, LLC dba Discovery Clinical Trials | San Antonio | Texas | 78258 | — |
| Advanced Research Institute | Ogden | Utah | 84405 | — |
| New River Valley Research Institute | Christiansburg | Virginia | 24073 | — |
| Blue Ridge Medical Research | Lynchburg | Virginia | 24502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03573908, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 1, 2020 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03573908 live on ClinicalTrials.gov.