ClinicalTrials.gov record
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity
ClinicalTrials.gov ID: NCT03574597
Public ClinicalTrials.gov record NCT03574597. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
SELECT - Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. The participant's chance of getting semaglutide or placebo is the same. The participant will get the study medicine in a pen. The participants will need to use the pen to inject the study medicine in a skinfold once a week. The study will last for about 2.5 to 5 years. Participants will have up to 25 clinic visits with the study doctor.
Study identification
- NCT ID
- NCT03574597
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 17,604 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 45 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 24, 2018 (Actual)
- Primary completion
- Jun 21, 2023 (Actual)
- Completion
- Jun 29, 2023 (Actual)
- Last update posted
- Aug 30, 2024
2018 – 2023
United States locations
- U.S. sites
- 205
- U.S. states
- 36
- U.S. cities
- 166
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Central Alabama Research | Birmingham | Alabama | 35209 | — |
| Univ of Alabama Birmingham | Birmingham | Alabama | 35294 | — |
| Healthscan Clinical Trials,LLC. | Montgomery | Alabama | 36106 | — |
| Synexus Clinical Research US, Inc./Tatum | Glendale | Arizona | 85306 | — |
| Synexus Clinical Research | Glendale | Arizona | 85308 | — |
| Synexus Rsch /Cnt Phnx Med C | Phoenix | Arizona | 85050 | — |
| National Heart Institute Cal | Beverly Hills | California | 90211 | — |
| FDRC | Costa Mesa | California | 92627 | — |
| Valley Clinical Trials | Covina | California | 91723 | — |
| Scripps Whittier Diabetes Inst | La Jolla | California | 92037 | — |
| First Valley Medical Group | Lancaster | California | 93534 | — |
| Torrance Clin Res Inst, Inc. | Lomita | California | 90717 | — |
| Long Beach VA healthcare System | Long Beach | California | 90822 | — |
| Angel City Research, Inc. | Los Angeles | California | 90010 | — |
| VAGLAHS Clinical Research Center (CRC) | Los Angeles | California | 90073 | — |
| Riverside University Health System Medical Center | Moreno Valley | California | 92555 | — |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | — |
| Desert Oasis Hlthcr Med Group | Palm Springs | California | 92262 | — |
| Western University of Health Sciences | Pomona | California | 91766 | — |
| Quartz Hill Walk-in Medical Group, inc. | Quartz Hill | California | 93536 | — |
| TriWest Research Associates | San Diego | California | 92108 | — |
| San Diego Family Care | San Diego | California | 92111 | — |
| Mills-Peninsula Medical Center | San Mateo | California | 94401 | — |
| NorCal Endocrinology and Internal Medicine | San Ramon | California | 94583 | — |
| Encompass Clinical Research_Spring Valley | Spring Valley | California | 91978 | — |
| Lundquist Inst-Biomed Innovtn | Torrance | California | 90502 | — |
| Synexus Clinical Research US, Inc._Horsham | Vista | California | 92083 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Optumcare Colorado Springs, LLC | Colorado Springs | Colorado | 80906 | — |
| Optumcare Colorado Springs | Colorado Springs | Colorado | 80906 | — |
| New West Physicians,Inc. | Golden | Colorado | 80401 | — |
| Optumcare Colorado Springs, LLC_Monument | Monument | Colorado | 80132 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| Yale University School Of Medicine | New Haven | Connecticut | 06510 | — |
| Chase Medical Research LLC | Waterbury | Connecticut | 06708 | — |
| Excel Med Ctr Clinical Trials | Boca Raton | Florida | 33434 | — |
| Bradenton Research Center | Bradenton | Florida | 34205 | — |
| Clearwater Cardiovascular Consultants | Clearwater | Florida | 33756 | — |
| Nature Coast Clin Rsrch_Crystal River | Crystal River | Florida | 34429 | — |
| Florida Premier Cardiology | Delray Beach | Florida | 33445 | — |
| Fleming Island Center for Clinical Research | Fleming Island | Florida | 32003 | — |
| Northeast Research Institute | Fleming Island | Florida | 32003 | — |
| Integrative Research Assoc Inc | Fort Lauderdale | Florida | 33312 | — |
| Clinical Research of Hollywood_Hollywood | Hollywood | Florida | 33024 | — |
| Est Cst Inst for Rsrch,Jksnvil | Jacksonville | Florida | 32216 | — |
| Jacksonville Ctr For Clin Res | Jacksonville | Florida | 32216 | — |
| Clinical Neuroscience Solutions, Inc. | Jacksonville | Florida | 32256 | — |
| Baptist Heart Specialists_Jacksonville | Jacksonville | Florida | 32258 | — |
| Baptist Heart Specialists_Jacksonville Beach | Jacksonville Beach | Florida | 32250 | — |
| Reyes Clinical Research, Inc | Miami | Florida | 33175 | — |
| International Research Associates, LLC_Miami | Miami | Florida | 33183 | — |
| AdventHealth Diab Inst | Orlando | Florida | 32804 | — |
| Oviedo Medical Research, LLC | Oviedo | Florida | 32765 | — |
| East Coast Institute for Research LLC | Saint Augustine | Florida | 32086 | — |
| Intercoastal Medical Group | Sarasota | Florida | 34239 | — |
| Cardio Partners Clin Res Inst | Wellington | Florida | 33449 | — |
| Ellipsis Group | Alpharetta | Georgia | 30022 | — |
| NSC Research, Inc | Johns Creek | Georgia | 30024 | — |
| Endocrine Research Solutions | Roswell | Georgia | 30076 | — |
| Family Health Care Center | Statesboro | Georgia | 30461 | — |
| Herman Clinical Research LLC | Suwanee | Georgia | 30024 | — |
| Atlanta Heart Specialists, LLC | Tucker | Georgia | 30084 | — |
| Northwest Heart Clinical Research, LLC | Arlington Heights | Illinois | 60005 | — |
| Apex Medical Research Inc | Chicago | Illinois | 60607 | — |
| Mercy Hospital and Medical Center | Chicago | Illinois | 60616 | — |
| Macoupin Research Group | Gillespie | Illinois | 62033 | — |
| Chicago Medical Research LLC | Hazel Crest | Illinois | 60429 | — |
| Lemah Creek Clinical Research | Oakbrook Terrace | Illinois | 60181 | — |
| Evanston Premier Hlthcr Res | Skokie | Illinois | 60077 | — |
| NorthShore Univ Hlth Sys | Skokie | Illinois | 60077 | — |
| Central Illinois Diabetes and Clinical Research | Springfield | Illinois | 62711 | — |
| Community Clinical Research_Anderson | Anderson | Indiana | 46011 | — |
| American Health Network of Indiana, LLC_Avon_0 | Avon | Indiana | 46123 | — |
| MediSphere Medical Research Center, LLC | Evansville | Indiana | 47714 | — |
| American Health Network of IN LLC_Franklin | Franklin | Indiana | 46131 | — |
| American Health Network of Indiana, LLC_Greenfield | Greenfield | Indiana | 46140 | — |
| Franciscan Health Michigan City | Michigan City | Indiana | 46360 | — |
| American Health Network of IN LLC | Muncie | Indiana | 47304 | — |
| American Health Network of Indiana, LLC | New Albany | Indiana | 47150 | — |
| Velocity Clinical_Valparaiso | Valparaiso | Indiana | 46383 | — |
| University of Iowa Prev Inter Ctr | Iowa City | Iowa | 52242 | — |
| The University Of Kansas Medical Center - Cray Dia | Kansas City | Kansas | 66160 | — |
| Midwest Heart & Vasc Spec | Overland Park | Kansas | 66211 | — |
| Cotton O'Neil Clin Research Ctr | Topeka | Kansas | 66606 | — |
| Robley Rex VA Medical Center | Louisville | Kentucky | 40206 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Norton Clinical Research Group | Louisville | Kentucky | 40213 | — |
| Cambridge Medical Trials | Alexandria | Louisiana | 71301 | — |
| Louisiana Heart Center | Hammond | Louisiana | 70403 | — |
| Barnum Medical Research, Inc. | Natchitoches | Louisiana | 71457-5881 | — |
| Louisiana Heart Center_Slidell | Slidell | Louisiana | 70458 | — |
| Anne Arundel Medical Center | Annapolis | Maryland | 21401 | — |
| University Of Maryland School of Medicine | Baltimore | Maryland | 21201 | — |
| Ascension Saint Agnes Heart Ca | Baltimore | Maryland | 21229 | — |
| MedStar Good Samaritan Hosp | Baltimore | Maryland | 21239 | — |
| Johns Hopkins University | Columbia | Maryland | 21044 | — |
| Centennial Medical Group | Elkridge | Maryland | 21075-6437 | — |
| MD Medical Research | Oxon Hill | Maryland | 20745 | — |
| Endo And Metab Cons | Rockville | Maryland | 20852 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115-5804 | — |
| Michigan Medicine | Ann Arbor | Michigan | 48109 | — |
| ClinSite LLC. | Canton | Michigan | 48187 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Aa Mrc Llc | Flint | Michigan | 48504 | — |
| Trinity Health Michigan Heart | Ypsilanti | Michigan | 48197 | — |
| Belzoni Clinical Research | Belzoni | Mississippi | 39038 | — |
| Amicis Centers of Clinical Research | St Louis | Missouri | 63128 | — |
| St Louis Heart & Vascular, P.C. | St Louis | Missouri | 63136 | — |
| Mercury Street Medical Group, PLLC_Butte | Butte | Montana | 59701 | — |
| VA NEB - Western IA Health Stm | Omaha | Nebraska | 68105 | — |
| University of NE Med Ctr | Omaha | Nebraska | 68198 | — |
| Synexus Clinical Research US | Henderson | Nevada | 89052 | — |
| Palm Research Center Inc-Vegas | Las Vegas | Nevada | 89128 | — |
| Southern NH Diabetes and Endo_Nashua | Nashua | New Hampshire | 03060 | — |
| UniMed Center | East Brunswick | New Jersey | 08816 | — |
| Holy Name Medical Center | Teaneck | New Jersey | 07666 | — |
| Albany Medical College - Endo | Albany | New York | 12203 | — |
| Dr. Alexander Perkelvald | Brooklyn | New York | 11229 | — |
| Long Island Cardiovascular Consultants PC | Lake Success | New York | 11042 | — |
| NYU Grossman School of Med | New York | New York | 10016 | — |
| NYU School of Medicine | New York | New York | 10016 | — |
| Comprehensive Weight Ctrl Prog | New York | New York | 10021 | — |
| Saratoga Clinical Research | Saratoga Springs | New York | 12866 | — |
| Southgate Medical Group, LLP | West Seneca | New York | 14224 | — |
| Great Lakes Medical Research | Westfield | New York | 14787 | — |
| UNC Eastowne Clinical Trials Unit | Chapel Hill | North Carolina | 27514 | — |
| OnSite Clinical Solutions, LLC | Charlotte | North Carolina | 28226 | — |
| Duke University_Durham | Durham | North Carolina | 27705 | — |
| Durham VA Medical Center - Duke University | Durham | North Carolina | 27705 | — |
| WakeMed Garner Hlthplx | Garner | North Carolina | 27529 | — |
| Physician's East Endocrinology | Greenville | North Carolina | 27834 | — |
| Duke University - S.E Cardio | Lumberton | North Carolina | 28358 | — |
| Burke Primary Care | Morganton | North Carolina | 28655 | — |
| Accellacare | Wilmington | North Carolina | 28401 | — |
| PMG Research of Winston-Salem | Winston-Salem | North Carolina | 27103 | — |
| The Carl & Edyth Lindner Center | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic_Cleveland | Cleveland | Ohio | 44195 | — |
| Providence Health Partners Ctr | Dayton | Ohio | 45439 | — |
| Advanced Med Res Maumee | Maumee | Ohio | 43537 | — |
| New Venture Medical Research | Wadsworth | Ohio | 44281 | — |
| Corvallis Clinic PC Clinical Research Department | Corvallis | Oregon | 97330-3737 | — |
| Oregon Health & Science Uni | Portland | Oregon | 97239 | — |
| Geisinger Clinic | Danville | Pennsylvania | 17822-2111 | — |
| Doylestown Hospital Pharmacy | Doylestown | Pennsylvania | 18901 | — |
| Harleysville Medical Associates | Harleysville | Pennsylvania | 19438 | — |
| Richard M Kastelic MD Assoc | Johnstown | Pennsylvania | 15905 | — |
| Hospital of the Univ PA | Philadelphia | Pennsylvania | 19104-4206 | — |
| Tristar Clin Investigations, PC | Philadelphia | Pennsylvania | 19114 | — |
| Parkside Family Medicine | Philadelphia | Pennsylvania | 19144 | — |
| Preferred Primary Care Physicians Inc. | Pittsburgh | Pennsylvania | 15243 | — |
| Internal Medicine Associates of Anderson | Anderson | South Carolina | 29621 | — |
| Synexus Clin Res US-Anderson | Anderson | South Carolina | 29621 | — |
| Medical Uni of SC Charleston | Charleston | South Carolina | 29425 | — |
| Palmetto Clinical Research | Greenville | South Carolina | 29615 | — |
| Accellacare US Inc._SC | Mt. Pleasant | South Carolina | 29464 | — |
| Holston Medical Group Pc | Bristol | Tennessee | 37620-7352 | — |
| The Stern Cardiovascular Group | Germantown | Tennessee | 38138 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| Clinical Neuroscience Solutions | Memphis | Tennessee | 38119 | — |
| InvestiClin Research | Nashville | Tennessee | 37203 | — |
| MidState Endocrine Associates | Nashville | Tennessee | 37203 | — |
| Trinity Clinical Research LLC | Tullahoma | Tennessee | 37388 | — |
| Amarillo Med Spec LLP | Amarillo | Texas | 79106 | — |
| Arlington Family Res. Ctr Inc | Arlington | Texas | 76012-4637 | — |
| Texas Diab & Endo, P.A. | Austin | Texas | 78749 | — |
| UT Health University of Texas | Bellaire | Texas | 77401 | — |
| Thyroid, Endocrinology, and Diabetes, PA | Dallas | Texas | 75208 | — |
| Texas Health Physicians Group_Dallas | Dallas | Texas | 75231 | — |
| UT Southwestern Med Cntr | Dallas | Texas | 75390-9302 | — |
| Northwest Houston Cardiology, P.A. | Houston | Texas | 77070 | — |
| PlanIt Research, PLLC | Houston | Texas | 77079 | — |
| DCOL Ctr for Clin Res | Longview | Texas | 75605 | — |
| Research Institute Of Dallas | Plano | Texas | 75093 | — |
| Quality Research Inc | San Antonio | Texas | 78209 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| San Antonio Prem Int Med | San Antonio | Texas | 78220 | — |
| Physician PrimeCare Research Institute, PLLC dba | San Antonio | Texas | 78228-6205 | — |
| Audie L. Murphy Va Hospital, Stvhcs | San Antonio | Texas | 78229 | — |
| VIP Trials | San Antonio | Texas | 78230 | — |
| Simcare Medical Research, LLC | Sugar Land | Texas | 77478 | — |
| Houston Center for Clinical Research LLC | Sugar Land | Texas | 77479 | — |
| Christus Heart and Vascular Institute | Tyler | Texas | 75701 | — |
| Hillcrest Family Health Center | Waco | Texas | 76708 | — |
| Wade Family Medicine | Bountiful | Utah | 84010 | — |
| Kalo Clinical Research | West Valley City | Utah | 84120 | — |
| U. of Vermont Med Ctr Burlington | South Burlington | Vermont | 05403-7205 | — |
| Inova Cardiology - Mt. Vernon | Alexandria | Virginia | 23306 | — |
| Cardiology Consultants of Danville Inc. | Danville | Virginia | 24541 | — |
| Inova Cardiology-Fairfax | Fairfax | Virginia | 22031 | — |
| Virginia Research Center | Midlothian | Virginia | 23114 | — |
| York Clinical Research LLC | Norfolk | Virginia | 23504 | — |
| Strelitz Diabetes Of Eastern V. | Norfolk | Virginia | 23510 | — |
| Dominion Medical Associates | Richmond | Virginia | 23219 | — |
| Clinical Research Partners, LLC | Richmond | Virginia | 23226 | — |
| National Clin Res Inc. | Richmond | Virginia | 23294 | — |
| VA Medical Center_Salem | Salem | Virginia | 24153-6404 | — |
| Bayview Physician Services | Virginia Beach | Virginia | 23454 | — |
| Sentara Medical Group_Norfolk | Virginia Beach | Virginia | 23454 | — |
| Selma Medical Associates | Winchester | Virginia | 22601-3834 | — |
| Amherst Family Practice P.C. | Winchester | Virginia | 22601 | — |
| Capital Clin Res Ctr,LLC | Olympia | Washington | 98502 | — |
| Confluence Health Hospital | Wenatchee | Washington | 98801 | — |
| St. Vincent Hosp-Prevea Health | Green Bay | Wisconsin | 54303 | — |
| Clinical Inv Spec, Inc.Kenosha | Kenosha | Wisconsin | 53144 | — |
| Aspirus Research Institute | Wausau | Wisconsin | 54401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 628 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03574597, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 30, 2024 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03574597 live on ClinicalTrials.gov.