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Completed Phase 3 Interventional Results available

Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity

ClinicalTrials.gov ID: NCT03574597

Public ClinicalTrials.gov record NCT03574597. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 20, 2026, 6:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

SELECT - Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity

Study identification

NCT ID
NCT03574597
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novo Nordisk A/S
Industry
Enrollment
17,604 participants

Conditions and interventions

Interventions

  • Placebo (semaglutide) Drug
  • Semaglutide Drug

Drug

Eligibility (public fields only)

Age range
45 Years and older
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 23, 2018
Primary completion
Jun 20, 2023
Completion
Jun 28, 2023
Last update posted
Aug 29, 2024

2018 – 2023

United States locations

U.S. sites
205
U.S. states
36
U.S. cities
166
Facility City State ZIP Site status
Central Alabama Research Birmingham Alabama 35209
Univ of Alabama Birmingham Birmingham Alabama 35294
Healthscan Clinical Trials,LLC. Montgomery Alabama 36106
Synexus Clinical Research US, Inc./Tatum Glendale Arizona 85306
Synexus Clinical Research Glendale Arizona 85308
Synexus Rsch /Cnt Phnx Med C Phoenix Arizona 85050
National Heart Institute Cal Beverly Hills California 90211
FDRC Costa Mesa California 92627
Valley Clinical Trials Covina California 91723
Scripps Whittier Diabetes Inst La Jolla California 92037
First Valley Medical Group Lancaster California 93534
Torrance Clin Res Inst, Inc. Lomita California 90717
Long Beach VA healthcare System Long Beach California 90822
Angel City Research, Inc. Los Angeles California 90010
VAGLAHS Clinical Research Center (CRC) Los Angeles California 90073
Riverside University Health System Medical Center Moreno Valley California 92555
Valley Clinical Trials, Inc. Northridge California 91325
Desert Oasis Hlthcr Med Group Palm Springs California 92262
Western University of Health Sciences Pomona California 91766
Quartz Hill Walk-in Medical Group, inc. Quartz Hill California 93536
TriWest Research Associates San Diego California 92108
San Diego Family Care San Diego California 92111
Mills-Peninsula Medical Center San Mateo California 94401
NorCal Endocrinology and Internal Medicine San Ramon California 94583
Encompass Clinical Research_Spring Valley Spring Valley California 91978
Lundquist Inst-Biomed Innovtn Torrance California 90502
Synexus Clinical Research US, Inc._Horsham Vista California 92083
University of Colorado Hospital Aurora Colorado 80045
Optumcare Colorado Springs, LLC Colorado Springs Colorado 80906
Optumcare Colorado Springs Colorado Springs Colorado 80906
New West Physicians,Inc. Golden Colorado 80401
Optumcare Colorado Springs, LLC_Monument Monument Colorado 80132
Bridgeport Hospital Bridgeport Connecticut 06610
Yale University School Of Medicine New Haven Connecticut 06510
Chase Medical Research LLC Waterbury Connecticut 06708
Excel Med Ctr Clinical Trials Boca Raton Florida 33434
Bradenton Research Center Bradenton Florida 34205
Clearwater Cardiovascular Consultants Clearwater Florida 33756
Nature Coast Clin Rsrch_Crystal River Crystal River Florida 34429
Florida Premier Cardiology Delray Beach Florida 33445
Fleming Island Center for Clinical Research Fleming Island Florida 32003
Northeast Research Institute Fleming Island Florida 32003
Integrative Research Assoc Inc Fort Lauderdale Florida 33312
Clinical Research of Hollywood_Hollywood Hollywood Florida 33024
Est Cst Inst for Rsrch,Jksnvil Jacksonville Florida 32216
Jacksonville Ctr For Clin Res Jacksonville Florida 32216
Clinical Neuroscience Solutions, Inc. Jacksonville Florida 32256
Baptist Heart Specialists_Jacksonville Jacksonville Florida 32258
Baptist Heart Specialists_Jacksonville Beach Jacksonville Beach Florida 32250
Reyes Clinical Research, Inc Miami Florida 33175
International Research Associates, LLC_Miami Miami Florida 33183
AdventHealth Diab Inst Orlando Florida 32804
Oviedo Medical Research, LLC Oviedo Florida 32765
East Coast Institute for Research LLC Saint Augustine Florida 32086
Intercoastal Medical Group Sarasota Florida 34239
Cardio Partners Clin Res Inst Wellington Florida 33449
Ellipsis Group Alpharetta Georgia 30022
NSC Research, Inc Johns Creek Georgia 30024
Endocrine Research Solutions Roswell Georgia 30076
Family Health Care Center Statesboro Georgia 30461
Herman Clinical Research LLC Suwanee Georgia 30024
Atlanta Heart Specialists, LLC Tucker Georgia 30084
Northwest Heart Clinical Research, LLC Arlington Heights Illinois 60005
Apex Medical Research Inc Chicago Illinois 60607
Mercy Hospital and Medical Center Chicago Illinois 60616
Macoupin Research Group Gillespie Illinois 62033
Chicago Medical Research LLC Hazel Crest Illinois 60429
Lemah Creek Clinical Research Oakbrook Terrace Illinois 60181
Evanston Premier Hlthcr Res Skokie Illinois 60077
NorthShore Univ Hlth Sys Skokie Illinois 60077
Central Illinois Diabetes and Clinical Research Springfield Illinois 62711
Community Clinical Research_Anderson Anderson Indiana 46011
American Health Network of Indiana, LLC_Avon_0 Avon Indiana 46123
MediSphere Medical Research Center, LLC Evansville Indiana 47714
American Health Network of IN LLC_Franklin Franklin Indiana 46131
American Health Network of Indiana, LLC_Greenfield Greenfield Indiana 46140
Franciscan Health Michigan City Michigan City Indiana 46360
American Health Network of IN LLC Muncie Indiana 47304
American Health Network of Indiana, LLC New Albany Indiana 47150
Velocity Clinical_Valparaiso Valparaiso Indiana 46383
University of Iowa Prev Inter Ctr Iowa City Iowa 52242
The University Of Kansas Medical Center - Cray Dia Kansas City Kansas 66160
Midwest Heart & Vasc Spec Overland Park Kansas 66211
Cotton O'Neil Clin Research Ctr Topeka Kansas 66606
Robley Rex VA Medical Center Louisville Kentucky 40206
L-MARC Research Center Louisville Kentucky 40213
Norton Clinical Research Group Louisville Kentucky 40213
Cambridge Medical Trials Alexandria Louisiana 71301
Louisiana Heart Center Hammond Louisiana 70403
Barnum Medical Research, Inc. Natchitoches Louisiana 71457-5881
Louisiana Heart Center_Slidell Slidell Louisiana 70458
Anne Arundel Medical Center Annapolis Maryland 21401
University Of Maryland School of Medicine Baltimore Maryland 21201
Ascension Saint Agnes Heart Ca Baltimore Maryland 21229
MedStar Good Samaritan Hosp Baltimore Maryland 21239
Johns Hopkins University Columbia Maryland 21044
Centennial Medical Group Elkridge Maryland 21075-6437
MD Medical Research Oxon Hill Maryland 20745
Endo And Metab Cons Rockville Maryland 20852
Brigham & Women's Hospital Boston Massachusetts 02115-5804
Michigan Medicine Ann Arbor Michigan 48109
ClinSite LLC. Canton Michigan 48187
Henry Ford Health System Detroit Michigan 48202
Aa Mrc Llc Flint Michigan 48504
Trinity Health Michigan Heart Ypsilanti Michigan 48197
Belzoni Clinical Research Belzoni Mississippi 39038
Amicis Centers of Clinical Research St Louis Missouri 63128
St Louis Heart & Vascular, P.C. St Louis Missouri 63136
Mercury Street Medical Group, PLLC_Butte Butte Montana 59701
VA NEB - Western IA Health Stm Omaha Nebraska 68105
University of NE Med Ctr Omaha Nebraska 68198
Synexus Clinical Research US Henderson Nevada 89052
Palm Research Center Inc-Vegas Las Vegas Nevada 89128
Southern NH Diabetes and Endo_Nashua Nashua New Hampshire 03060
UniMed Center East Brunswick New Jersey 08816
Holy Name Medical Center Teaneck New Jersey 07666
Albany Medical College - Endo Albany New York 12203
Dr. Alexander Perkelvald Brooklyn New York 11229
Long Island Cardiovascular Consultants PC Lake Success New York 11042
NYU Grossman School of Med New York New York 10016
NYU School of Medicine New York New York 10016
Comprehensive Weight Ctrl Prog New York New York 10021
Saratoga Clinical Research Saratoga Springs New York 12866
Southgate Medical Group, LLP West Seneca New York 14224
Great Lakes Medical Research Westfield New York 14787
UNC Eastowne Clinical Trials Unit Chapel Hill North Carolina 27514
OnSite Clinical Solutions, LLC Charlotte North Carolina 28226
Duke University_Durham Durham North Carolina 27705
Durham VA Medical Center - Duke University Durham North Carolina 27705
WakeMed Garner Hlthplx Garner North Carolina 27529
Physician's East Endocrinology Greenville North Carolina 27834
Duke University - S.E Cardio Lumberton North Carolina 28358
Burke Primary Care Morganton North Carolina 28655
Accellacare Wilmington North Carolina 28401
PMG Research of Winston-Salem Winston-Salem North Carolina 27103
The Carl & Edyth Lindner Center Cincinnati Ohio 45219
Cleveland Clinic_Cleveland Cleveland Ohio 44195
Providence Health Partners Ctr Dayton Ohio 45439
Advanced Med Res Maumee Maumee Ohio 43537
New Venture Medical Research Wadsworth Ohio 44281
Corvallis Clinic PC Clinical Research Department Corvallis Oregon 97330-3737
Oregon Health & Science Uni Portland Oregon 97239
Geisinger Clinic Danville Pennsylvania 17822-2111
Doylestown Hospital Pharmacy Doylestown Pennsylvania 18901
Harleysville Medical Associates Harleysville Pennsylvania 19438
Richard M Kastelic MD Assoc Johnstown Pennsylvania 15905
Hospital of the Univ PA Philadelphia Pennsylvania 19104-4206
Tristar Clin Investigations, PC Philadelphia Pennsylvania 19114
Parkside Family Medicine Philadelphia Pennsylvania 19144
Preferred Primary Care Physicians Inc. Pittsburgh Pennsylvania 15243
Internal Medicine Associates of Anderson Anderson South Carolina 29621
Synexus Clin Res US-Anderson Anderson South Carolina 29621
Medical Uni of SC Charleston Charleston South Carolina 29425
Palmetto Clinical Research Greenville South Carolina 29615
Accellacare US Inc._SC Mt. Pleasant South Carolina 29464
Holston Medical Group Pc Bristol Tennessee 37620-7352
The Stern Cardiovascular Group Germantown Tennessee 38138
Holston Medical Group Kingsport Tennessee 37660
Clinical Neuroscience Solutions Memphis Tennessee 38119
InvestiClin Research Nashville Tennessee 37203
MidState Endocrine Associates Nashville Tennessee 37203
Trinity Clinical Research LLC Tullahoma Tennessee 37388
Amarillo Med Spec LLP Amarillo Texas 79106
Arlington Family Res. Ctr Inc Arlington Texas 76012-4637
Texas Diab & Endo, P.A. Austin Texas 78749
UT Health University of Texas Bellaire Texas 77401
Thyroid, Endocrinology, and Diabetes, PA Dallas Texas 75208
Texas Health Physicians Group_Dallas Dallas Texas 75231
UT Southwestern Med Cntr Dallas Texas 75390-9302
Northwest Houston Cardiology, P.A. Houston Texas 77070
PlanIt Research, PLLC Houston Texas 77079
DCOL Ctr for Clin Res Longview Texas 75605
Research Institute Of Dallas Plano Texas 75093
Quality Research Inc San Antonio Texas 78209
Sun Research Institute San Antonio Texas 78215
San Antonio Prem Int Med San Antonio Texas 78220
Physician PrimeCare Research Institute, PLLC dba San Antonio Texas 78228-6205
Audie L. Murphy Va Hospital, Stvhcs San Antonio Texas 78229
VIP Trials San Antonio Texas 78230
Simcare Medical Research, LLC Sugar Land Texas 77478
Houston Center for Clinical Research LLC Sugar Land Texas 77479
Christus Heart and Vascular Institute Tyler Texas 75701
Hillcrest Family Health Center Waco Texas 76708
Wade Family Medicine Bountiful Utah 84010
Kalo Clinical Research West Valley City Utah 84120
U. of Vermont Med Ctr Burlington South Burlington Vermont 05403-7205
Inova Cardiology - Mt. Vernon Alexandria Virginia 23306
Cardiology Consultants of Danville Inc. Danville Virginia 24541
Inova Cardiology-Fairfax Fairfax Virginia 22031
Virginia Research Center Midlothian Virginia 23114
York Clinical Research LLC Norfolk Virginia 23504
Strelitz Diabetes Of Eastern V. Norfolk Virginia 23510
Dominion Medical Associates Richmond Virginia 23219
Clinical Research Partners, LLC Richmond Virginia 23226
National Clin Res Inc. Richmond Virginia 23294
VA Medical Center_Salem Salem Virginia 24153-6404
Bayview Physician Services Virginia Beach Virginia 23454
Sentara Medical Group_Norfolk Virginia Beach Virginia 23454
Selma Medical Associates Winchester Virginia 22601-3834
Amherst Family Practice P.C. Winchester Virginia 22601
Capital Clin Res Ctr,LLC Olympia Washington 98502
Confluence Health Hospital Wenatchee Washington 98801
St. Vincent Hosp-Prevea Health Green Bay Wisconsin 54303
Clinical Inv Spec, Inc.Kenosha Kenosha Wisconsin 53144
Aspirus Research Institute Wausau Wisconsin 54401

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 628 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03574597, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 29, 2024 · Synced Apr 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03574597 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →