Study Evaluating Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years And Older With Moderate to Severe Atopic Dermatitis
Public ClinicalTrials.gov record NCT03575871. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL GROUP, MULTI-CENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-04965842 MONOTHERAPY IN SUBJECTS AGED 12 YEARS AND OLDER, WITH MODERATE TO SEVERE ATOPIC DERMATITIS
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
B7451013 is a Phase 3 study to evaluate PF-04965842 in patients aged 12 years and older with a minimum body weight of 40 kg who have moderate to severe atopic dermatitis. The efficacy and safety of two dosage strengths of PF-04965842, 100 mg and 200 mg taken orally once daily, will be evaluated relative to placebo over 12 weeks of study participation. Eligible patients will have an option to enter a long-term extension study after completing 12 weeks of treatment.
Study identification
- NCT ID
- NCT03575871
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 391 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 29, 2018 (Actual)
- Primary completion
- Aug 13, 2019 (Actual)
- Completion
- Aug 13, 2019 (Actual)
- Last update posted
- Apr 21, 2020
2018 – 2019
United States locations
- U.S. sites
- 28
- U.S. states
- 13
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Emmaus Research Center, Inc. | Anaheim | California | 92804 | — |
| Advanced Research Center, Inc. - Los Alamitos Site | Los Alamitos | California | 90720 | — |
| Peninsula Research Associates, Inc. | Rolling Hills Estates | California | 90274 | — |
| Clinical Science Institute | Santa Monica | California | 90404 | — |
| Asthma and Allergy Associates, PC | Colorado Springs | Colorado | 80907 | — |
| Colorado Springs Dermatology Clinic, PC | Colorado Springs | Colorado | 80910 | — |
| Olympian Clinical Research | Clearwater | Florida | 33756 | — |
| Clinical Neuroscience Solutions, Inc. | Jacksonville | Florida | 32256 | — |
| Precision Imaging | Jacksonville | Florida | 32256 | — |
| Solutions Through Advanced Research, Inc. | Jacksonville | Florida | 32256 | — |
| Clinical Neuroscience Solutions, Inc | Orlando | Florida | 32801 | — |
| ForCare Clinical Research | Tampa | Florida | 33613 | — |
| Imaging Center of Idaho | Caldwell | Idaho | 83605 | — |
| ASR, LLC | Nampa | Idaho | 83687 | — |
| Meridian Clinical Research | Baton Rouge | Louisiana | 70808 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| MediSearch Clinical Trials | Saint Joseph | Missouri | 64506 | — |
| Sadick Research Group | New York | New York | 10075 | — |
| PMG Research of Wilmington, LLC | Wilmington | North Carolina | 28411 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| The Ohio State University Dermatology East | Gahanna | Ohio | 43230 | — |
| Tanenbaum Dermatology Center | Memphis | Tennessee | 38117 | — |
| Clinical Neuroscience Solutions, Inc. | Memphis | Tennessee | 38119 | — |
| Austin Institute for Clinical Research, Inc. - Central | Austin | Texas | 78705 | — |
| Center for Clinical Studies, LTD. LLP | Houston | Texas | 77004 | — |
| West Houston Dermatology, PA | Houston | Texas | 77082 | — |
| Summit Clinical Research, LLC | Franklin | Virginia | 23851 | — |
| Virginia Dermatology and Skin Cancer Center | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 87 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03575871, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 21, 2020 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03575871 live on ClinicalTrials.gov.