Zelquistinel in the Treatment of Major Depressive Disorder
Public ClinicalTrials.gov record NCT03586427. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Placebo-Controlled, Fixed-Dose Study of AGN-241751 in Adult Participants With Major Depressive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy at 1 day post initial oral dose of zelquistinel (AGN-241751) compared with placebo in participants with Major Depressive Disorder (MDD).
Study identification
- NCT ID
- NCT03586427
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 251 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 12, 2018
- Primary completion
- Jul 21, 2019
- Completion
- Aug 20, 2019
- Last update posted
- Apr 26, 2026
2018 – 2019
United States locations
- U.S. sites
- 25
- U.S. states
- 12
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Health Initiatives Research PLLC | Fayetteville | Arkansas | 72703 | — |
| Synexus US - Cerritos | Cerritos | California | 90703 | — |
| Wake Research - Pharmacology Research Institute | Encino | California | 91316 | — |
| Wake Research - Pharmacology Research Institute | Newport Beach | California | 92660 | — |
| Pacific Research Partners, LLC | Oakland | California | 94607 | — |
| North County Clinical Research, Inc. | Oceanside | California | 92054 | — |
| Collaborative Neuroscience Network | Torrance | California | 90502 | — |
| Elite Clinical Trials, Inc. | Wildomar | California | 92595 | — |
| Synexus US - Atlanta | Atlanta | Georgia | 30328 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| Pillar Clinical Research | Lincolnwood | Illinois | 60712 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | — |
| Hassman Research Institute | Berlin | New Jersey | 08009 | — |
| Center for Emotional Fitness | Cherry Hill | New Jersey | 08002 | — |
| Neurobehavioral Research, Inc | Cedarhurst | New York | 11516 | — |
| Synexus US - Queens | Jamaica | New York | 11432 | — |
| Eastside Comprehensive Medical Center | New York | New York | 10128 | — |
| Finger Lakes Clinical Research | Rochester | New York | 14618 | — |
| Neuro-Behavioral Clinical Research, Inc | North Canton | Ohio | 44720 | — |
| IPS Research | Oklahoma City | Oklahoma | 73106 | — |
| Clinical Neuroscience Solutions, Inc - Memphis, TN | Memphis | Tennessee | 38119 | — |
| Research Strategies of Memphis, LLC | Memphis | Tennessee | 38119 | — |
| Donald J. Garcia, Jr., MD, PA | Austin | Texas | 78737 | — |
| FutureSearch Trials of Dallas, LP | Dallas | Texas | 75231 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03586427, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 26, 2026 · Synced Sep 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03586427 live on ClinicalTrials.gov.