Disrupt CAD III With the Shockwave Coronary IVL System
Public ClinicalTrials.gov record NCT03595176. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Prospective, Multicenter, Single-Arm, Global IDE Study of the Shockwave Coronary Intravascular Lithotripsy (IVL) System With the Shockwave C2 Coronary IVL Catheter in Calcified Coronary Arteries
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study design is a prospective, multicenter, single-arm, global IDE study to evaluate the safety and effectiveness of the Shockwave Medical Coronary Intravascular Lithotripsy (IVL) System in de novo, calcified, stenotic coronary arteries prior to stenting. Disrupt CAD III is being conducted as a staged pivotal study.
Study identification
- NCT ID
- NCT03595176
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 431 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 9, 2019 (Actual)
- Primary completion
- May 7, 2020 (Actual)
- Completion
- Apr 10, 2022 (Actual)
- Last update posted
- May 19, 2023
2019 – 2022
United States locations
- U.S. sites
- 39
- U.S. states
- 24
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Honor Health | Scottsdale | Arizona | 85258 | — |
| Scripps Clinic | La Jolla | California | 92037 | — |
| University of California, San Diego (UCSD) - Medical Center | La Jolla | California | 92037 | — |
| St. Joseph Hospital | Orange | California | 92868 | — |
| VA Palo Alto Health Care System | Palo Alto | California | 94304 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06520 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Piedmont Heart Institute | Atlanta | Georgia | 30309 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Advocate Health and Hospitals Corporation - Edward Hospital | Oakbrook Terrace | Illinois | 60540 | — |
| St. Vincent Heart Center of Indiana, LLC | Indianapolis | Indiana | 46290 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| MedStar Union Memorial Hospital | Baltimore | Maryland | 21218 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Minneapolis Heart Institute | Minneapolis | Minnesota | 55407 | — |
| North Mississippi Medical Center | Tupelo | Mississippi | 38801 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Deborah Heart and Lung Center | Browns Mills | New Jersey | 08015 | — |
| New York University (NYU) Langone Medical Center | New York | New York | 10016 | — |
| Columbia University Medical Center/ New York Presbyterian | New York | New York | 10065 | — |
| St. Francis Hospital | Roslyn | New York | 11576 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Durham VA Health Care System | Durham | North Carolina | 27705 | — |
| NC Heart and Vascular | Raleigh | North Carolina | 27607 | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | 19096 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Pinnacle Health Cardiovascular Institute Inc. | Wormleysburg | Pennsylvania | 17043 | — |
| The Miriam Hospital | Providence | Rhode Island | 02906 | — |
| Baylor Heart and Vascular Hospital | Dallas | Texas | 75226 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| University of Vermont | Burlington | Vermont | 05401 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Charleston Area Medical Center (CAMC) - Health Education & Research Institute | Charleston | West Virginia | 25304 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03595176, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 19, 2023 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03595176 live on ClinicalTrials.gov.