Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial
Public ClinicalTrials.gov record NCT03596450. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Clinical Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to compare the effects of semaglutide (Ozempic®) with the effects of other treatments for type 2 diabetes in a normal practice setting. The participant will be assigned by chance (like flipping a coin) to one of the following treatment groups: Group 1: semaglutide (Ozempic®) (by injection into skin) Group 2: standard of care antidiabetic medication (oral or injectable). The participant has an equal chance of being in either of the treatment groups. Neither the participant nor the study doctor or study staff will be able to pick which group the participant is in, but the participant will know which study drug the participant has been assigned to. The study doctor will provide the participant with a prescription for the study diabetes medication based on the treatment group the participant is assigned. The participation will last about 2 years.
Study identification
- NCT ID
- NCT03596450
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 1,278 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 12, 2018
- Primary completion
- Jun 8, 2022
- Completion
- Jun 8, 2023
- Last update posted
- Jul 2, 2024
2018 – 2023
United States locations
- U.S. sites
- 121
- U.S. states
- 20
- U.S. cities
- 107
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| American Clinical Trials | Buena Park | California | 90620 | — |
| St. Jos Heritage Hlthcr_Fllrtn | Fullerton | California | 92835 | — |
| SC Clinical Research, Inc. | Garden Grove | California | 92844 | — |
| New Hope Consulting & Clinical Trials | Lancaster | California | 93534 | — |
| OM Research LLC | Lancaster | California | 93534 | — |
| Pacific Clinical Studies | Los Alamitos | California | 90720 | — |
| Pacific Medical Center | Milpitas | California | 95035 | — |
| Facey Medical Foundation | Mission Hills | California | 91345 | — |
| Monterey Endocrine & Diabetes Institute, Inc | Monterey | California | 93940 | — |
| Do-Eun Lee | Napa | California | 94558 | — |
| Format Medical Research | Oxnard | California | 93030 | — |
| Joselito C Cabaccan, MD | San Jose | California | 95148 | — |
| Premier Medical Center, Inc. | Toluca Lake | California | 91602 | — |
| Adnab Research/Prestige Care Physician | Torrance | California | 90505 | — |
| Altura Centers For Health | Tulare | California | 93274 | — |
| Tariq Javed, MD Inc. | Visalia | California | 93291 | — |
| Endocrinology & Diabetes Specialists | Walnut Creek | California | 94598 | — |
| University of Colorado Hospital | Denver | Colorado | 80220 | — |
| Denver Endocrinology Diabetes and Thyroid Center | Englewood | Colorado | 80113 | — |
| ProHealth Physicians/OptumCare | Bristol | Connecticut | 06010 | — |
| Western Connecticut Health Network_Danbury | Danbury | Connecticut | 06810 | — |
| Endocrine Associates of Connecticut | Hamden | Connecticut | 06517 | — |
| Ismail Tarkhan MD | Milford | Connecticut | 06460 | — |
| Steven L. Saunders MD LLC | Milford | Connecticut | 06460 | — |
| The Kaufmann Clinic, Inc. | Atlanta | Georgia | 30106 | — |
| Primary Care Research | Atlanta | Georgia | 30312 | — |
| Southern Family Medical Center | Augusta | Georgia | 04915 | — |
| River Birch Research Alliance, LLC | Blue Ridge | Georgia | 30513 | — |
| Gwinnett Research Insti/Buford Family Pract Urgent Care Ctr | Buford | Georgia | 30519 | — |
| Centricity Research | Columbus | Georgia | 31904 | — |
| Medical Care of LaGrange | La Grange | Georgia | 30240 | — |
| Beaver Ruin Primary Care | Lilburn | Georgia | 30047 | — |
| Privia Medical Group of Georgia LLC | Locust Grove | Georgia | 30248 | — |
| DC Research Works | Marietta | Georgia | 30060 | — |
| Urban Family Practice Assoc | Marietta | Georgia | 30067 | — |
| Atlanta Center for Clinical Research | Roswell | Georgia | 30075 | — |
| Sandersville Family Practice | Sandersville | Georgia | 31082 | — |
| Meridian Clin Res, LLC | Savannah | Georgia | 31406 | — |
| Family Health Care Center | Statesboro | Georgia | 30461 | — |
| Eagles Landing Diabetes/Endocrinology | Stockbridge | Georgia | 30281 | — |
| Herman Clinical Research LLC | Suwanee | Georgia | 30024 | — |
| Sugarloaf Medical, PC | Suwanee | Georgia | 30024 | — |
| East Georgia Healthcare Center Inc | Swainsboro | Georgia | 30401 | — |
| Coastal Care Medical Clinic | Waycross | Georgia | 31501 | — |
| St. Vincent Research Institute | Anderson | Indiana | 46016 | — |
| American Health Network of Indiana, LLC_Avon_0 | Avon | Indiana | 46123 | — |
| Adams County Family Physicians | Berne | Indiana | 46711 | — |
| Deaconess Clinic, Inc. | Evansville | Indiana | 47725 | — |
| Associated Surgeons & Physicians LLC | Fort Wayne | Indiana | 46825 | — |
| American Health Network of IN LLC_Franklin | Franklin | Indiana | 46131 | — |
| American Health Network of Indiana, LLC_Greenfield | Greenfield | Indiana | 46140 | — |
| La Porte County Institute For Clinical Research | Michigan City | Indiana | 46360 | — |
| Beacon Medical Group Swartz-Weikamp | Mishawaka | Indiana | 46544 | — |
| American Health Network of IN LLC | Muncie | Indiana | 47304 | — |
| American Health Network of Indiana, LLC | New Albany | Indiana | 47150 | — |
| Reid Endocrinology Center | Richmond | Indiana | 47374 | — |
| Regional Endorine and Diabetes Associates | Ashland | Kentucky | 41101 | — |
| Tri State Primary Caregrayson Health Park | Ashland | Kentucky | 41101 | — |
| St Elizabeth Physicians Heart | Covington | Kentucky | 41011 | — |
| The Endocrine & Diabetes Center | Owensboro | Kentucky | 42303 | — |
| Paris Family Physicians PLLC | Paris | Kentucky | 40361 | — |
| Gaurang B. Shah, MD | Richmond | Kentucky | 40475 | — |
| WCMP Family Medicine | Belfast | Maine | 04915 | — |
| Tri-County Research, Inc. | Sterling Heights | Michigan | 48310-3503 | — |
| Diabetes & Endo Specialists Inc | Chesterfield | Missouri | 63017 | — |
| University Of Missouri - Columbia | Columbia | Missouri | 65201 | — |
| Jefferson City Medical Group, PC | Jefferson City | Missouri | 65109 | — |
| Trinity Healthcare | Springfield | Missouri | 65803 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| South County Endocrinology and Obesity Medicine, LLC | St Louis | Missouri | 63128 | — |
| Palm Research Center Inc-Vegas | Las Vegas | Nevada | 89148 | — |
| Albany Medical College - Endo | Albany | New York | 12203 | — |
| Prominis Medical Services PC | Brooklyn | New York | 11221 | — |
| Northwell Health Div of Endo | Great Neck | New York | 11021 | — |
| Advanced Internal Medicine Group | Great Neck | New York | 11023 | — |
| NYC Research, Inc. | New York | New York | 10016 | — |
| NYU Grossman School of Med | New York | New York | 10016 | — |
| EDOC LLP | Yonkers | New York | 10704 | — |
| OnSite Clinical Solutions, LLC_Charlotte_0 | Charlotte | North Carolina | 28210 | — |
| OnSite Clinical Solutions, LLC_Charlotte | Charlotte | North Carolina | 28277 | — |
| Valley Weight Loss Clinic | Fargo | North Dakota | 58104 | — |
| Catherine LaRuffa, M.D., Inc. | Blanchester | Ohio | 45107 | — |
| Diab & Endo Assoc of Stark Co | Canton | Ohio | 44718 | — |
| Medical Frontiers, LLC | Carlisle | Ohio | 45005 | — |
| University Hospitals of Cleveland Case Medical Center | Cleveland | Ohio | 44106 | — |
| Central Ohio Clinical Research LLC | Columbus | Ohio | 43213 | — |
| Centricity Research | Columbus | Ohio | 43213 | — |
| Franklin Family Practice | Franklin | Ohio | 45005 | — |
| Prestige Clinical Research | Franklin | Ohio | 45005 | — |
| Functional Endocrinology | Mason | Ohio | 45040 | — |
| New Venture Medical Research | Wadsworth | Ohio | 44281 | — |
| Harleysville Medical Associates | Harleysville | Pennsylvania | 19438 | — |
| Primary Care Research South, Inc | McMurray | Pennsylvania | 15317 | — |
| Preferred Primary Care Physicians_Pittsburgh | Pittsburgh | Pennsylvania | 15236 | — |
| Athens Medical Group | Athens | Tennessee | 37303 | — |
| PMG Research of Bristol | Bristol | Tennessee | 24201 | — |
| Murphy Research Center | Humboldt | Tennessee | 38343 | — |
| Ascend Research Centers, Inc. | McMinnville | Tennessee | 37110 | — |
| Christus Trinity Clinic Hill Country Landa | New Braunfels | Texas | 78130 | — |
| Simcare Medical Research, LLC | Sugar Land | Texas | 77478 | — |
| Chrysalis Clinical Research | St. George | Utah | 84790 | — |
| The Endocrinology Group | Arlington | Virginia | 22205 | — |
| Chatham Family Medical Center | Chatham | Virginia | 24531 | — |
| Swift Creek Family Care | Colonial Heights | Virginia | 23834 | — |
| Lawson Family Medicine & Aesthetics | Daleville | Virginia | 23083 | — |
| Privia Medical Group LLC | Danville | Virginia | 24541 | — |
| Seven Corners Medical | Falls Church | Virginia | 22044 | — |
| Hampton Family Practice | Hampton | Virginia | 23666 | — |
| Medical Associates of Central Virginia, Inc. | Lynchburg | Virginia | 24501 | — |
| C. Lee Ginsburgh | Newport News | Virginia | 23606 | — |
| Family Medicine Healthcare | Portsmouth | Virginia | 23701 | — |
| Family Health Clinic | Radford | Virginia | 24141 | — |
| Halifax Internal Medicine | South Boston | Virginia | 24592 | — |
| Hampton Roads Center for Clinical Research | Suffolk | Virginia | 23435 | — |
| Endocrinology Consultants | Virginia Beach | Virginia | 23454 | — |
| Corporation Lane Research Center | Virginia Beach | Virginia | 23462 | — |
| Piedmont Family Practice PLC | Warrenton | Virginia | 20186 | — |
| Family Care of Williamsburg | Williamsburg | Virginia | 49820 | — |
| St. Vincent Hosp-Prevea Health | Green Bay | Wisconsin | 54303 | — |
| Ascension Medical Group- Germantown Clinic | Milwaukee | Wisconsin | 53211 | — |
| Medical College of Wisconsin & Zablocki VAMC | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03596450, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 2, 2024 · Synced Sep 3, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03596450 live on ClinicalTrials.gov.