ClinicalTrials.gov record
Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial
ClinicalTrials.gov ID: NCT03596450
Public ClinicalTrials.gov record NCT03596450. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Clinical Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to compare the effects of semaglutide (Ozempic®) with the effects of other treatments for type 2 diabetes in a normal practice setting. The participant will be assigned by chance (like flipping a coin) to one of the following treatment groups: Group 1: semaglutide (Ozempic®) (by injection into skin) Group 2: standard of care antidiabetic medication (oral or injectable). The participant has an equal chance of being in either of the treatment groups. Neither the participant nor the study doctor or study staff will be able to pick which group the participant is in, but the participant will know which study drug the participant has been assigned to. The study doctor will provide the participant with a prescription for the study diabetes medication based on the treatment group the participant is assigned. The participation will last about 2 years.
Study identification
- NCT ID
- NCT03596450
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 1,278 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 13, 2018 (Actual)
- Primary completion
- Jun 9, 2022 (Actual)
- Completion
- Jun 9, 2023 (Actual)
- Last update posted
- Sep 30, 2026
2018 – 2023
United States locations
- U.S. sites
- 180
- U.S. states
- 24
- U.S. cities
- 147
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| American Clinical Trials | Buena Park | California | 90620 | — |
| Endocrine Specialty Consultant Inc. | Burbank | California | 91505 | — |
| FDRC | Costa Mesa | California | 92627 | — |
| Bay Area Clinical Research | Dublin | California | 94568 | — |
| Providence Medical Foundation | Fullerton | California | 92835 | — |
| SC Clinical Research, Inc. | Garden Grove | California | 92844 | — |
| SCKE Odyssey Medical Group | Laguna Hills | California | 92653 | — |
| New Hope Consulting & Clinical Trials | Lancaster | California | 93534 | — |
| OM Research LLC | Lancaster | California | 93534 | — |
| Torrance Clin Res Inst, Inc. | Lomita | California | 90717 | — |
| West Coast Endocrine, Inc. | Long Beach | California | 90815 | — |
| Pacific Clinical Studies | Los Alamitos | California | 90720 | — |
| Angel City Research | Los Angeles | California | 90057 | — |
| University of Californ LA-UCLA | Los Angeles | California | 90095 | — |
| Patel, Rahul | Manteca | California | 95336 | — |
| Pacific Medical Center | Milpitas | California | 95035 | — |
| Facey Medical Foundation | Mission Hills | California | 91345 | — |
| Monterey Endocrine & Diabetes Institute, Inc | Monterey | California | 93940 | — |
| Do-Eun Lee | Napa | California | 94558 | — |
| Charles Andrews, MD | Newport Beach | California | 92660 | — |
| Hoag Medical Group | Newport Beach | California | 92663 | — |
| Adam B. Sherman D O Professional Corp. | Oxnard | California | 93030 | — |
| Format Medical Research | Oxnard | California | 93030 | — |
| Stanford Univ School of Med | Palo Alto | California | 94304 | — |
| Posada, Juan | San Jose | California | 95116 | — |
| Joselito C Cabaccan, MD | San Jose | California | 95148 | — |
| Care Access Research Santa Clarita | Santa Clarita | California | 91321 | — |
| Premier Medical Center, Inc. | Toluca Lake | California | 91602 | — |
| Adnab Research/Prestige Care Physician | Torrance | California | 90505 | — |
| Altura Centers For Health | Tulare | California | 93274 | — |
| Tariq Javed, MD Inc. | Visalia | California | 93291 | — |
| Endocrinology & Diabetes Specialists | Walnut Creek | California | 94598 | — |
| PIH Health Physicians Endocrinology | Whittier | California | 90606 | — |
| Optumcare Clinical Trials,LLC-Golden | Colorado Springs | Colorado | 80906 | — |
| Delta Waves, Inc. | Colorado Springs | Colorado | 80918 | — |
| University of Colorado Hospital | Denver | Colorado | 80220 | — |
| Denver Endocrinology Diabetes and Thyroid Center | Englewood | Colorado | 80113 | — |
| ProHealth Physicians/OptumCare | Bristol | Connecticut | 06010 | — |
| Western Connecticut Health Network_Danbury | Danbury | Connecticut | 06810 | — |
| Endocrine Associates of Connecticut | Hamden | Connecticut | 06517 | — |
| Ismail Tarkhan MD | Milford | Connecticut | 06460 | — |
| Steven L. Saunders MD LLC | Milford | Connecticut | 06460 | — |
| Westside Center For Clinical Research | Jacksonville | Florida | 32205 | — |
| The Kaufmann Clinic, Inc. | Atlanta | Georgia | 30106 | — |
| Primary Care Research | Atlanta | Georgia | 30312 | — |
| Southern Family Medical Center | Augusta | Georgia | 04915 | — |
| River Birch Research Alliance, LLC | Blue Ridge | Georgia | 30513 | — |
| Gwinnett Research Insti/Buford Family Pract Urgent Care Ctr | Buford | Georgia | 30519 | — |
| Centricity Research | Columbus | Georgia | 31904 | — |
| Medical Care of LaGrange | La Grange | Georgia | 30240 | — |
| Beaver Ruin Primary Care | Lilburn | Georgia | 30047 | — |
| Privia Medical Group of Georgia LLC | Locust Grove | Georgia | 30248 | — |
| DC Research Works | Marietta | Georgia | 30060 | — |
| Urban Family Practice Assoc | Marietta | Georgia | 30067 | — |
| Atlanta Center for Clinical Research | Roswell | Georgia | 30075 | — |
| Sandersville Family Practice | Sandersville | Georgia | 31082 | — |
| Meridian Clin Res, LLC | Savannah | Georgia | 31406 | — |
| Family Health Care Center | Statesboro | Georgia | 30461 | — |
| Eagles Landing Diabetes/Endocrinology | Stockbridge | Georgia | 30281 | — |
| First Medical Research Center | Stone Mountain | Georgia | 30083 | — |
| Herman Clinical Research LLC | Suwanee | Georgia | 30024 | — |
| Sugarloaf Medical, PC | Suwanee | Georgia | 30024 | — |
| East Georgia Healthcare Center Inc | Swainsboro | Georgia | 30401 | — |
| Coastal Care Medical Clinic | Waycross | Georgia | 31501 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| St. Vincent Research Institute | Anderson | Indiana | 46016 | — |
| American Health Network of Indiana, LLC_Avon_0 | Avon | Indiana | 46123 | — |
| Tom H. Jones | Avon | Indiana | 46123 | — |
| Adams County Family Physicians | Berne | Indiana | 46711 | — |
| Deaconess Clinic, Inc. | Evansville | Indiana | 47725 | — |
| Associated Surgeons & Physicians LLC | Fort Wayne | Indiana | 46825 | — |
| American Health Network of IN LLC_Franklin | Franklin | Indiana | 46131 | — |
| American Health Network of Indiana, LLC_Greenfield | Greenfield | Indiana | 46140 | — |
| Indiana Internal Medicine Consultants LLC | Greenwood | Indiana | 46143 | — |
| La Porte County Institute For Clinical Research | Michigan City | Indiana | 46360 | — |
| Beacon Medical Group Swartz-Weikamp | Mishawaka | Indiana | 46544 | — |
| Indiana University Health Ball Memorial Hospital | Muncie | Indiana | 47303 | — |
| American Health Network of IN LLC | Muncie | Indiana | 47304 | — |
| Elpidio M. Feliciano | Muncie | Indiana | 47304 | — |
| American Health Network of Indiana, LLC | New Albany | Indiana | 47150 | — |
| Reid Endocrinology Center | Richmond | Indiana | 47374 | — |
| Regional Endorine and Diabetes Associates | Ashland | Kentucky | 41101 | — |
| Tri State Primary Caregrayson Health Park | Ashland | Kentucky | 41101 | — |
| St Elizabeth Physicians Heart | Covington | Kentucky | 41011 | — |
| Patel Medical Center | Irvington | Kentucky | 40146 | — |
| The Endocrine & Diabetes Center | Owensboro | Kentucky | 42303 | — |
| Paris Family Physicians PLLC | Paris | Kentucky | 40361 | — |
| Gaurang B. Shah, MD | Richmond | Kentucky | 40475 | — |
| Versailles Family Medicine | Versailles | Kentucky | 40383 | — |
| WCMP Family Medicine | Belfast | Maine | 04915 | — |
| MD Medical Research | Oxon Hill | Maryland | 20745 | — |
| Tri-County Research, Inc. | Sterling Heights | Michigan | 48310-3503 | — |
| Diabetes & Endo Specialists Inc | Chesterfield | Missouri | 63017 | — |
| University Of Missouri - Columbia | Columbia | Missouri | 65201 | — |
| Jefferson City Medical Group, PC | Jefferson City | Missouri | 65109 | — |
| Trinity Healthcare | Springfield | Missouri | 65803 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| South County Endocrinology and Obesity Medicine, LLC | St Louis | Missouri | 63128 | — |
| Desert Endocrinology Clinical Research Center | Las Vegas | Nevada | 89117 | — |
| Palm Research Center Inc-Vegas | Las Vegas | Nevada | 89148 | — |
| Southern New Hampshire Diabete | Nashua | New Hampshire | 03060 | — |
| AMC Community Endocrinology | Albany | New York | 12203 | — |
| Prominis Medical Services PC | Brooklyn | New York | 11221 | — |
| Northwell Health Div of Endo | Great Neck | New York | 11021 | — |
| Advanced Internal Medicine Group | Great Neck | New York | 11023 | — |
| Smart Medical Research Inc. | Jackson Heights | New York | 11372 | — |
| Rockcastle Family Endocrinology | Mount Vernon | New York | 40456 | — |
| NYC Research, Inc. | New York | New York | 10016 | — |
| NYU Grossman School of Med | New York | New York | 10016 | — |
| Elligo Health Research Inc | New York | New York | 10028 | — |
| Endocrine Associates of Long Island, PC | Smithtown | New York | 11787 | — |
| EDOC LLP | Yonkers | New York | 10704 | — |
| OnSite Clinical Solutions, LLC_Charlotte_0 | Charlotte | North Carolina | 28210 | — |
| OnSite Clinical Solutions, LLC_Charlotte | Charlotte | North Carolina | 28277 | — |
| Burke Primary Care | Morganton | North Carolina | 28655 | — |
| Lillestol Research LLC | Fargo | North Dakota | 58104 | — |
| Valley Weight Loss Clinic | Fargo | North Dakota | 58104 | — |
| Catherine LaRuffa, M.D., Inc. | Blanchester | Ohio | 45107 | — |
| Diab & Endo Assoc of Stark Co | Canton | Ohio | 44718 | — |
| Medical Frontiers, LLC | Carlisle | Ohio | 45005 | — |
| University of Cincinnati/UC Health | Cincinnati | Ohio | 45241 | — |
| University Hospitals of Cleveland Case Medical Center | Cleveland | Ohio | 44106 | — |
| Central Ohio Clinical Research LLC | Columbus | Ohio | 43213 | — |
| Centricity Research | Columbus | Ohio | 43213 | — |
| Providence Health Partners Ctr | Dayton | Ohio | 45439 | — |
| Franklin Family Practice | Franklin | Ohio | 45005 | — |
| Prestige Clinical Research | Franklin | Ohio | 45005 | — |
| Albert J Weisbrot | Mason | Ohio | 45040-6815 | — |
| Functional Endocrinology | Mason | Ohio | 45040 | — |
| Toledo Clinic | Toledo | Ohio | 43623 | — |
| New Venture Medical Research | Wadsworth | Ohio | 44281 | — |
| Harleysville Medical Associates | Harleysville | Pennsylvania | 19438 | — |
| Detweiler Family Med | Lansdale | Pennsylvania | 19446-1002 | — |
| Primary Care Research South, Inc | McMurray | Pennsylvania | 15317 | — |
| Master Centre for USA | Pittsburgh | Pennsylvania | 15236 | — |
| Preferred Primary Care Physicians_Pittsburgh | Pittsburgh | Pennsylvania | 15236 | — |
| Athens Medical Group | Athens | Tennessee | 37303 | — |
| PMG Research of Bristol | Bristol | Tennessee | 24201 | — |
| Murphy Research Center | Humboldt | Tennessee | 38343 | — |
| Ascend Research Centers, Inc. | McMinnville | Tennessee | 37110 | — |
| Rockwood Medical Clinic | Fort Worth | Texas | 76164 | — |
| TVC Clinical Research | Gonzales | Texas | 78629 | — |
| PrimeCare Medical Group | Houston | Texas | 77024 | — |
| Southwest Urgent Care and Family practice | Houston | Texas | 77081 | — |
| Christus Trinity Clinic Hill Country Landa | New Braunfels | Texas | 78130 | — |
| Hill Country Medical Associates | New Braunfels | Texas | 78130 | — |
| HAS Research | San Antonio | Texas | 78240 | — |
| Simcare Medical Research, LLC | Sugar Land | Texas | 77478 | — |
| Chrysalis Clinical Research | St. George | Utah | 84790 | — |
| The Endocrinology Group | Arlington | Virginia | 22205 | — |
| Chatham Family Medical Center | Chatham | Virginia | 24531 | — |
| Swift Creek Family Care | Colonial Heights | Virginia | 23834 | — |
| Lawson Family Medicine & Aesthetics | Daleville | Virginia | 23083 | — |
| Privia Medical Group LLC | Danville | Virginia | 24541 | — |
| Seven Corners Medical | Falls Church | Virginia | 22044 | — |
| Courtside Family Medicine PLLC | Gloucester | Virginia | 23061 | — |
| Hampton Family Practice | Hampton | Virginia | 23666 | — |
| Hartford Internal Medicine | Hampton | Virginia | 23666 | — |
| Medical Associates of Central Virginia, Inc. | Lynchburg | Virginia | 24501 | — |
| Virginia Research Center | Midlothian | Virginia | 23114 | — |
| C. Lee Ginsburgh | Newport News | Virginia | 23606 | — |
| York Clinical Research LLC | Norfolk | Virginia | 23504 | — |
| Eastern Virginia Medical School | Norfolk | Virginia | 23510 | — |
| Clinical Research Partners | North Chesterfield | Virginia | 23235 | — |
| Family Medicine Healthcare | Portsmouth | Virginia | 23701 | — |
| Family Health Clinic | Radford | Virginia | 24141 | — |
| Dominion Medical Associates | Richmond | Virginia | 23219 | — |
| Halifax Internal Medicine | South Boston | Virginia | 24592 | — |
| Southside Primary Care | South Chesterfield | Virginia | 23803 | — |
| Colonial Medical Clinic | South Chesterfield | Virginia | 23834 | — |
| Hampton Roads Center for Clinical Research | Suffolk | Virginia | 23435 | — |
| Endocrinology Consultants | Virginia Beach | Virginia | 23454 | — |
| Corporation Lane Research Center | Virginia Beach | Virginia | 23462 | — |
| Piedmont Family Practice PLC | Warrenton | Virginia | 20186 | — |
| Tidewater Physicians Multispecialty Group | Williamsburg | Virginia | 23188 | — |
| Family Care of Williamsburg | Williamsburg | Virginia | 49820 | — |
| Selma Medical Associates | Winchester | Virginia | 22601-3834 | — |
| St. Vincent Hosp-Prevea Health | Green Bay | Wisconsin | 54303 | — |
| Ascension Medical Group- Germantown Clinic | Milwaukee | Wisconsin | 53211 | — |
| Medical College of Wisconsin & Zablocki VAMC | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03596450, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 30, 2026 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03596450 live on ClinicalTrials.gov.