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Active, not recruiting Phase 3 Interventional Results available

A Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

ClinicalTrials.gov ID: NCT03596645

Public ClinicalTrials.gov record NCT03596645. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 6:00 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Randomized, Open-Label Study to Assess the Efficacy, Safety, and Pharmacokinetics of Golimumab Treatment, a Human Anti-TNFα Monoclonal Antibody, Administered Subcutaneously in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate efficacy of golimumab in inducing clinical remission as assessed by the Mayo score, in pediatric participants with moderately to severely active ulcerative colitis (UC). In addition, the safety profile of golimumab, in pediatric participants with moderately to severely active UC will be assessed.

Study identification

NCT ID
NCT03596645
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Enrollment
84 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
2 Years to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 28, 2018
Primary completion
Nov 20, 2023
Completion
Jan 31, 2027
Last update posted
Aug 30, 2026

2018 – 2027

United States locations

U.S. sites
12
U.S. states
9
U.S. cities
12
Facility City State ZIP Site status
University of California San Francisco San Francisco California 94158
Children's Hospital Colorado and University of Colorado Aurora Colorado 80045
Rocky Mountain Pediatric Gastroenterology Lone Tree Colorado 80124
Connecticut Children's Medical Center Hartford Connecticut 06106
Nemours DuPont Hospital for Children Wilmington Delaware 19803
Children's Center for Digestive Health Care Atlanta Georgia 30342
Mayo Clinic Rochester Minnesota 55905
Columbia University Medical Center New York New York 10032
GI For Kids Knoxville Tennessee 37922
Children's Medical Center of Dallas Dallas Texas 75207
Cook Childrens Medical Center Fort Worth Texas 76104
DHAT Research Institute Garland Texas 75044

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 46 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03596645, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 30, 2026 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03596645 live on ClinicalTrials.gov.

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