ClinicalTrials.gov record
Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery
ClinicalTrials.gov ID: NCT03604991
Public ClinicalTrials.gov record NCT03604991. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II/III Study of Peri-Operative Nivolumab and Ipilimumab in Patients With Locoregional Esophageal and Gastroesophageal Junction Adenocarcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. Immunotherapy with antibodies, such as nivolumab and ipilimumab, may remove the brake on the body's immune system and may interfere with the ability of tumor cells to grow and spread. Chemotherapy and radiation therapy may reduce the tumor size and the amount of normal tissue that needs to be removed during surgery. A combined treatment with nivolumab and ipilimumab, chemotherapy, and radiation therapy might be more effective in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery.
Study identification
- NCT ID
- NCT03604991
- Recruitment status
- Suspended
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 278 participants
Conditions and interventions
Conditions
- Clinical Stage II Esophageal Adenocarcinoma AJCC v8
- Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
- Clinical Stage III Esophageal Adenocarcinoma AJCC v8
- Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
- Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8
- Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
- Esophageal Adenocarcinoma
- Gastroesophageal Junction Adenocarcinoma
Interventions
- Biospecimen Collection Procedure
- Carboplatin Drug
- Computed Tomography Procedure
- Ipilimumab Biological
- Nivolumab Biological
- Paclitaxel Drug
- Positron Emission Tomography Procedure
- Radiation Therapy Radiation
Procedure · Drug · Biological + 1 more
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 3, 2019 (Actual)
- Primary completion
- Mar 31, 2027 (Estimated)
- Completion
- Mar 31, 2027 (Estimated)
- Last update posted
- Oct 16, 2026
2019 – 2027
United States locations
- U.S. sites
- 488
- U.S. states
- 47
- U.S. cities
- 344
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Anchorage Associates in Radiation Medicine | Anchorage | Alaska | 98508 | — |
| Alaska Breast Care and Surgery LLC | Anchorage | Alaska | 99508 | — |
| Alaska Oncology and Hematology LLC | Anchorage | Alaska | 99508 | — |
| Alaska Women's Cancer Care | Anchorage | Alaska | 99508 | — |
| Anchorage Oncology Centre | Anchorage | Alaska | 99508 | — |
| Katmai Oncology Group | Anchorage | Alaska | 99508 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | — |
| Cancer Center at Saint Joseph's | Phoenix | Arizona | 85004 | — |
| Mercy Hospital Fort Smith | Fort Smith | Arkansas | 72903 | — |
| CHI Saint Vincent Cancer Center Hot Springs | Hot Springs | Arkansas | 71913 | — |
| NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro | Jonesboro | Arkansas | 72401 | — |
| PCR Oncology | Arroyo Grande | California | 93420 | — |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | 91505 | — |
| Community Cancer Institute | Clovis | California | 93611 | — |
| University Oncology Associates | Clovis | California | 93611 | — |
| Los Angeles General Medical Center | Los Angeles | California | 90033 | — |
| USC / Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Stanford Cancer Institute Palo Alto | Palo Alto | California | 94304 | — |
| VA Palo Alto Health Care System | Palo Alto | California | 94304 | — |
| Mercy Cancer Center - Sacramento | Sacramento | California | 95816 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| Pacific Central Coast Health Center-San Luis Obispo | San Luis Obispo | California | 93401 | — |
| Mission Hope Medical Oncology - Santa Maria | Santa Maria | California | 93444 | — |
| Saint Helena Hospital | St. Helena | California | 94574 | — |
| Presbyterian Intercommunity Hospital | Whittier | California | 90602 | — |
| Woodland Memorial Hospital | Woodland | California | 95695 | — |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | — |
| Rocky Mountain Cancer Centers-Penrose | Colorado Springs | Colorado | 80907 | — |
| Saint Francis Cancer Center | Colorado Springs | Colorado | 80923 | — |
| AdventHealth Porter | Denver | Colorado | 80210 | — |
| CommonSpirit Saint Anthony Hospital Cancer Center | Lakewood | Colorado | 80228 | — |
| AdventHealth Littleton | Littleton | Colorado | 80122 | — |
| Longmont United Hospital | Longmont | Colorado | 80501 | — |
| AdventHealth Parker | Parker | Colorado | 80138 | — |
| Saint Mary Corwin Medical Center | Pueblo | Colorado | 81004 | — |
| Beebe Medical Center | Lewes | Delaware | 19958 | — |
| Beebe South Coastal Health Campus | Millville | Delaware | 19967 | — |
| Delaware Clinical and Laboratory Physicians PA | Newark | Delaware | 19713 | — |
| Helen F Graham Cancer Center | Newark | Delaware | 19713 | — |
| Medical Oncology Hematology Consultants PA | Newark | Delaware | 19713 | — |
| Christiana Care Health System-Christiana Hospital | Newark | Delaware | 19718 | — |
| Beebe Health Campus | Rehoboth Beach | Delaware | 19971 | — |
| TidalHealth Nanticoke / Allen Cancer Center | Seaford | Delaware | 19973 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| AdventHealth Altamonte | Altamonte Springs | Florida | 32701 | — |
| Mount Sinai Comprehensive Cancer Center at Aventura | Aventura | Florida | 33180 | — |
| Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| Regional Cancer Center-Lee Memorial Health System | Fort Myers | Florida | 33905 | — |
| UF Health Cancer Institute - Gainesville | Gainesville | Florida | 32610 | — |
| AdventHealth Kissimmee | Kissimmee | Florida | 34744 | — |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| AdventHealth Orlando | Orlando | Florida | 32803 | — |
| AdventHealth East Orlando | Orlando | Florida | 32822 | — |
| Emory Proton Therapy Center | Atlanta | Georgia | 30308 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Emory Saint Joseph's Hospital | Atlanta | Georgia | 30342 | — |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia | 31405 | — |
| Hawaii Cancer Care Inc - Waterfront Plaza | Honolulu | Hawaii | 96813 | — |
| Island Urology | Honolulu | Hawaii | 96813 | — |
| Queen's Cancer Cenrer - POB I | Honolulu | Hawaii | 96813 | — |
| Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Straub Clinic and Hospital | Honolulu | Hawaii | 96813 | — |
| University of Hawaii Cancer Center | Honolulu | Hawaii | 96813 | — |
| Hawaii Cancer Care Inc-Liliha | Honolulu | Hawaii | 96817 | — |
| Kuakini Medical Center | Honolulu | Hawaii | 96817 | — |
| Queen's Cancer Center - Kuakini | Honolulu | Hawaii | 96817 | — |
| The Cancer Center of Hawaii-Liliha | Honolulu | Hawaii | 96817 | — |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96826 | — |
| Wilcox Memorial Hospital and Kauai Medical Clinic | Lihue | Hawaii | 96766 | — |
| Hawaii Cancer Care - Westridge | ‘Aiea | Hawaii | 96701 | — |
| Pali Momi Medical Center | ‘Aiea | Hawaii | 96701 | — |
| Queen's Cancer Center - Pearlridge | ‘Aiea | Hawaii | 96701 | — |
| The Cancer Center of Hawaii-Pali Momi | ‘Aiea | Hawaii | 96701 | — |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | — |
| Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | 83619 | — |
| Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | 83642 | — |
| Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | 83687 | — |
| Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | 83301 | — |
| Illinois CancerCare-Bloomington | Bloomington | Illinois | 61704 | — |
| Illinois CancerCare-Canton | Canton | Illinois | 61520 | — |
| Memorial Hospital of Carbondale | Carbondale | Illinois | 62902 | — |
| SIH Cancer Institute | Carterville | Illinois | 62918 | — |
| Illinois CancerCare-Carthage | Carthage | Illinois | 62321 | — |
| Centralia Oncology Clinic | Centralia | Illinois | 62801 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Illinois | Chicago | Illinois | 60612 | — |
| Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | 62526 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Illinois CancerCare-Dixon | Dixon | Illinois | 61021 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Illinois CancerCare-Eureka | Eureka | Illinois | 61530 | — |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | — |
| Western Illinois Cancer Treatment Center | Galesburg | Illinois | 61401 | — |
| Edward Hines Jr VA Hospital | Hines | Illinois | 60141 | — |
| Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | 61443 | — |
| Northwestern Medicine Lake Forest Hospital | Lake Forest | Illinois | 60045 | — |
| Illinois CancerCare-Macomb | Macomb | Illinois | 61455 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| SSM Health Good Samaritan | Mount Vernon | Illinois | 62864 | — |
| Cancer Care Center of O'Fallon | O'Fallon | Illinois | 62269 | — |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | — |
| Illinois CancerCare-Pekin | Pekin | Illinois | 61554 | — |
| OSF Saint Francis Radiation Oncology at Pekin | Pekin | Illinois | 61554 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| OSF Saint Francis Radiation Oncology at Peoria Cancer Center | Peoria | Illinois | 61615 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Illinois CancerCare-Peru | Peru | Illinois | 61354 | — |
| Valley Radiation Oncology | Peru | Illinois | 61354 | — |
| Illinois CancerCare-Princeton | Princeton | Illinois | 61356 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| Springfield Clinic | Springfield | Illinois | 62702 | — |
| Springfield Memorial Hospital | Springfield | Illinois | 62781 | — |
| Illinois CancerCare - Washington | Washington | Illinois | 61571 | — |
| IU Health North Hospital | Carmel | Indiana | 46032 | — |
| Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| Reid Health | Richmond | Indiana | 47374 | — |
| Mercy Cancer Center-West Lakes | Clive | Iowa | 50325 | — |
| UI Health Care Mission Cancer and Blood - West Des Moines Clinic | Clive | Iowa | 50325 | — |
| Greater Regional Medical Center | Creston | Iowa | 50801 | — |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| UI Health Care Mission Cancer and Blood - Laurel Clinic | Des Moines | Iowa | 50314 | — |
| Mercy Medical Center-West Lakes | West Des Moines | Iowa | 50266 | — |
| Central Care Cancer Center - Garden City | Garden City | Kansas | 67846 | — |
| Central Care Cancer Center - Great Bend | Great Bend | Kansas | 67530 | — |
| CommonSpirit Saint Joseph Hospital - Lexington | Lexington | Kentucky | 40504 | — |
| Saint Joseph Radiation Oncology Resource Center | Lexington | Kentucky | 40504 | — |
| CommonSpirit Saint Joseph Medical Center - East Lexington | Lexington | Kentucky | 40509 | — |
| Jewish Hospital | Louisville | Kentucky | 40202 | — |
| UofL Health Medical Center Northeast | Louisville | Kentucky | 40245 | — |
| Ochsner Medical Center Kenner | Kenner | Louisiana | 70065 | — |
| Ochsner Medical Center Jefferson | New Orleans | Louisiana | 70121 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| MaineHealth Coastal Cancer Treatment Center | Bath | Maine | 04530 | — |
| MaineHealth Maine Medical Center - Biddeford | Biddeford | Maine | 04005 | — |
| Lafayette Family Cancer Center-EMMC | Brewer | Maine | 04412 | — |
| MaineHealth Maine Medical Center - Portland | Portland | Maine | 04102 | — |
| MaineHealth Cancer Care and IV Therapy - Sanford | Sanford | Maine | 04073 | — |
| MaineHealth Cancer Care Center of York County | Sanford | Maine | 04073 | — |
| MaineHealth Maine Medical Center- Scarborough | Scarborough | Maine | 04074 | — |
| MaineHealth Cancer Care and IV Therapy - South Portland | South Portland | Maine | 04106 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Lowell General Hospital | Lowell | Massachusetts | 01854 | — |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor | Ann Arbor | Michigan | 48106 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton | Michigan | 48114 | — |
| Trinity Health Medical Center - Brighton | Brighton | Michigan | 48114 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton | Michigan | 48188 | — |
| Trinity Health Medical Center - Canton | Canton | Michigan | 48188 | — |
| Caro Cancer Center | Caro | Michigan | 48723 | — |
| Chelsea Hospital | Chelsea | Michigan | 48118 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Chelsea | Michigan | 48118 | — |
| Henry Ford Health Saint John Hospital | Detroit | Michigan | 48236 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Henry Ford Saint John Hospital - Van Elslander | Grosse Pointe Woods | Michigan | 48236 | — |
| University of Michigan Health - Sparrow Lansing | Lansing | Michigan | 48912 | — |
| Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | 48154 | — |
| Henry Ford Saint John Hospital - Macomb Medical | Macomb | Michigan | 48044 | — |
| Saint Mary's Oncology/Hematology Associates of Marlette | Marlette | Michigan | 48453 | — |
| Henry Ford Health Providence Novi Hospital | Novi | Michigan | 48374 | — |
| Michigan Healthcare Professionals Pontiac | Pontiac | Michigan | 48341 | — |
| Trinity Health Saint Joseph Mercy Oakland Hospital | Pontiac | Michigan | 48341 | — |
| MyMichigan Medical Center Saginaw | Saginaw | Michigan | 48601 | — |
| Oncology Hematology Associates of Saginaw Valley PC | Saginaw | Michigan | 48604 | — |
| Henry Ford Health Providence Southfield Hospital | Southfield | Michigan | 48075 | — |
| MyMichigan Medical Center Tawas | Tawas City | Michigan | 48764 | — |
| Henry Ford Health Warren Hospital | Warren | Michigan | 48093 | — |
| Saint Mary's Oncology/Hematology Associates of West Branch | West Branch | Michigan | 48661 | — |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti | Michigan | 48197 | — |
| Sanford Joe Lueken Cancer Center | Bemidji | Minnesota | 56601 | — |
| Essentia Health Saint Joseph's Medical Center | Brainerd | Minnesota | 56401 | — |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Minnesota Oncology - Burnsville | Burnsville | Minnesota | 55337 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Essentia Health - Deer River Clinic | Deer River | Minnesota | 56636 | — |
| Essentia Health Saint Mary's - Detroit Lakes Clinic | Detroit Lakes | Minnesota | 56501 | — |
| Essentia Health Cancer Center | Duluth | Minnesota | 55805 | — |
| Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | 55805 | — |
| Miller-Dwan Hospital | Duluth | Minnesota | 55805 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Minnesota Oncology - Edina | Edina | Minnesota | 55435 | — |
| Lake Region Healthcare Corporation-Cancer Care | Fergus Falls | Minnesota | 56537 | — |
| Essentia Health - Fosston | Fosston | Minnesota | 56542 | — |
| Unity Hospital | Fridley | Minnesota | 55432 | — |
| Essentia Health Hibbing Clinic | Hibbing | Minnesota | 55746 | — |
| Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota | 55369 | — |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | — |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | — |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| Health Partners Inc | Minneapolis | Minnesota | 55454 | — |
| Monticello Cancer Center | Monticello | Minnesota | 55362 | — |
| Essentia Health - Park Rapids | Park Rapids | Minnesota | 56470 | — |
| North Memorial Medical Health Center | Robbinsdale | Minnesota | 55422 | — |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Essentia Health Sandstone | Sandstone | Minnesota | 55072 | — |
| Saint Francis Regional Medical Center | Shakopee | Minnesota | 55379 | — |
| Lakeview Hospital | Stillwater | Minnesota | 55082 | — |
| Essentia Health Virginia Clinic | Virginia | Minnesota | 55792 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | — |
| Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | — |
| Baptist Memorial Hospital and Cancer Center-Golden Triangle | Columbus | Mississippi | 39705 | — |
| Baptist Cancer Center-Grenada | Grenada | Mississippi | 38901 | — |
| Baptist Memorial Hospital and Cancer Center-Union County | New Albany | Mississippi | 38652 | — |
| Baptist Memorial Hospital and Cancer Center-Oxford | Oxford | Mississippi | 38655 | — |
| Baptist Memorial Hospital and Cancer Center-Desoto | Southhaven | Mississippi | 38671 | — |
| Mercy Oncology and Hematology - Clayton-Clarkson | Ballwin | Missouri | 63011 | — |
| Central Care Cancer Center - Bolivar | Bolivar | Missouri | 65613 | — |
| Mercy Cancer Center - Cape Girardeau | Cape Girardeau | Missouri | 63703 | — |
| Saint Francis Medical Center | Cape Girardeau | Missouri | 63703 | — |
| Siteman Cancer Center at Saint Peters Hospital | City of Saint Peters | Missouri | 63376 | — |
| Siteman Cancer Center at West County Hospital | Creve Coeur | Missouri | 63141 | — |
| Parkland Health Center - Farmington | Farmington | Missouri | 63640 | — |
| MU Health Care Goldschmidt Cancer Center | Jefferson City | Missouri | 65109 | — |
| Freeman Health System | Joplin | Missouri | 64804 | — |
| Mercy Hospital Joplin | Joplin | Missouri | 64804 | — |
| Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | 65401 | — |
| Phelps Health Delbert Day Cancer Institute | Rolla | Missouri | 65401 | — |
| Heartland Regional Medical Center | Saint Joseph | Missouri | 64506 | — |
| Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | 63670 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| CoxHealth South Hospital | Springfield | Missouri | 65807 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Mercy Hospital South | St Louis | Missouri | 63128 | — |
| Siteman Cancer Center-South County | St Louis | Missouri | 63129 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Siteman Cancer Center at Christian Hospital | St Louis | Missouri | 63136 | — |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | — |
| Missouri Baptist Sullivan Hospital | Sullivan | Missouri | 63080 | — |
| Saint Patrick Hospital - Community Hospital | Missoula | Montana | 59802 | — |
| Nebraska Medicine-Bellevue | Bellevue | Nebraska | 68123 | — |
| Nebraska Cancer Specialists/Oncology Hematology West PC | Grand Island | Nebraska | 68803 | — |
| CHI Health Good Samaritan | Kearney | Nebraska | 68847 | — |
| Nebraska Medicine-Village Pointe | Omaha | Nebraska | 68118 | — |
| Alegent Health Immanuel Medical Center | Omaha | Nebraska | 68122 | — |
| Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | 68124 | — |
| Alegent Health Lakeside Hospital | Omaha | Nebraska | 68130 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Comprehensive Cancer Centers of Nevada - Henderson | Henderson | Nevada | 89052 | — |
| Oncology Las Vegas - Henderson | Henderson | Nevada | 89074 | — |
| OptumCare Cancer Care at Charleston | Las Vegas | Nevada | 89102 | — |
| Radiation Oncology Centers of Nevada Central | Las Vegas | Nevada | 89106 | — |
| Radiation Oncology Centers of Nevada Southeast | Las Vegas | Nevada | 89119 | — |
| Comprehensive Cancer Centers of Nevada - Northwest | Las Vegas | Nevada | 89128 | — |
| OptumCare Cancer Care at MountainView | Las Vegas | Nevada | 89128 | — |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation | Las Vegas | Nevada | 89135 | — |
| Comprehensive Cancer Centers of Nevada - Town Center | Las Vegas | Nevada | 89144 | — |
| Comprehensive Cancer Centers of Nevada-Summerlin | Las Vegas | Nevada | 89144 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89148 | — |
| Comprehensive Cancer Centers of Nevada - Central Valley | Las Vegas | Nevada | 89169 | — |
| OptumCare Cancer Care at Fort Apache | Las Vegas | Nevada | 89183 | — |
| Renown Regional Medical Center | Reno | Nevada | 89502 | — |
| Saint Mary's Regional Medical Center | Reno | Nevada | 89503 | — |
| Radiation Oncology Associates | Reno | Nevada | 89509 | — |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center | Lebanon | New Hampshire | 03756 | — |
| Ocean University Medical Center | Brick | New Jersey | 08724 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740 | — |
| Southern Ocean County Medical Center | Manahawkin | New Jersey | 08050 | — |
| Jersey Shore Medical Center | Neptune City | New Jersey | 07753 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| Riverview Medical Center/Booker Cancer Center | Red Bank | New Jersey | 07701 | — |
| Community Medical Center | Toms River | New Jersey | 08755 | — |
| Lovelace Medical Center-Saint Joseph Square | Albuquerque | New Mexico | 87102 | — |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87106 | — |
| New Mexico Oncology Hematology Consultants | Albuquerque | New Mexico | 87109 | — |
| Presbyterian Kaseman Hospital | Albuquerque | New Mexico | 87110 | — |
| Presbyterian Rust Medical Center/Jorgensen Cancer Center | Rio Rancho | New Mexico | 87124 | — |
| Sands Cancer Center | Canandaigua | New York | 14424 | — |
| Noyes Memorial Hospital/Myers Cancer Center | Dansville | New York | 14437 | — |
| Glens Falls Hospital | Glens Falls | New York | 12801 | — |
| Northwell Health/Center for Advanced Medicine | Lake Success | New York | 11042 | — |
| Garnet Health Medical Center | Middletown | New York | 10940 | — |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | — |
| NYP/Weill Cornell Medical Center | New York | New York | 10065 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| State University of New York Upstate Medical University | Syracuse | New York | 13210 | — |
| Montefiore Medical Center-Einstein Campus | The Bronx | New York | 10461 | — |
| Montefiore Medical Center-Weiler Hospital | The Bronx | New York | 10461 | — |
| Montefiore Medical Center - Moses Campus | The Bronx | New York | 10467 | — |
| Novant Health Presbyterian Medical Center | Charlotte | North Carolina | 28204 | — |
| Novant Health Cancer Institute - Huntersville | Huntersville | North Carolina | 28078 | — |
| Novant Health Presbyterian Medical Center Huntersville | Huntersville | North Carolina | 28078 | — |
| Novant Health Cancer Institute - Kernersville | Kernersville | North Carolina | 27284 | — |
| Matthews Radiation Oncology Center | Matthews | North Carolina | 28105 | — |
| Novant Health Cancer Institute - Matthews | Matthews | North Carolina | 28105 | — |
| Novant Health Cancer Institute - Mooresville | Mooresville | North Carolina | 28117 | — |
| Novant Health Cancer Institute - Mount Airy | Mount Airy | North Carolina | 27030 | — |
| Novant Health Cancer Institute - Wilkesboro | North Wilkesboro | North Carolina | 28659 | — |
| Rowan Regional Medical Center | Salisbury | North Carolina | 28144 | — |
| Novant Health Cancer Institute - Statesville | Statesville | North Carolina | 28625 | — |
| Novant Health Cancer Institute - Thomasville | Thomasville | North Carolina | 27360 | — |
| Novant Health Forsyth Medical Center | Winston-Salem | North Carolina | 27103 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Essentia Health Cancer Center-South University Clinic | Fargo | North Dakota | 58103 | — |
| Sanford Broadway Medical Center | Fargo | North Dakota | 58122 | — |
| Sanford Roger Maris Cancer Center | Fargo | North Dakota | 58122 | — |
| Essentia Health - Jamestown Clinic | Jamestown | North Dakota | 58401 | — |
| Indu and Raj Soin Medical Center | Beavercreek | Ohio | 45431 | — |
| Saint Elizabeth Boardman Hospital | Boardman | Ohio | 44512 | — |
| Dayton Physicians LLC-Miami Valley South | Centerville | Ohio | 45459 | — |
| Miami Valley Hospital South | Centerville | Ohio | 45459 | — |
| University of Cincinnati Cancer Center-UC Medical Center | Cincinnati | Ohio | 45219 | — |
| Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | 45220 | — |
| Oncology Hematology Care Inc-Kenwood | Cincinnati | Ohio | 45236 | — |
| Bethesda North Hospital | Cincinnati | Ohio | 45242 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Dayton Physician LLC - Englewood | Dayton | Ohio | 45415 | — |
| Miami Valley Hospital North | Dayton | Ohio | 45415 | — |
| Armes Family Cancer Center | Findlay | Ohio | 45840 | — |
| Blanchard Valley Hospital | Findlay | Ohio | 45840 | — |
| Orion Cancer Care | Findlay | Ohio | 45840 | — |
| Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | 45005-1066 | — |
| Dayton Physicians LLC-Atrium | Franklin | Ohio | 45005 | — |
| Dayton Physicians LLC-Wayne | Greenville | Ohio | 45331 | — |
| Wayne Hospital | Greenville | Ohio | 45331 | — |
| Cleveland Clinic Cancer Center Independence | Independence | Ohio | 44131 | — |
| Greater Dayton Cancer Center | Kettering | Ohio | 45409 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Cleveland Clinic Cancer Center Mansfield | Mansfield | Ohio | 44906 | — |
| Hillcrest Hospital Cancer Center | Mayfield Heights | Ohio | 44124 | — |
| North Coast Cancer Care | Sandusky | Ohio | 44870 | — |
| Springfield Regional Cancer Center | Springfield | Ohio | 45504 | — |
| Springfield Regional Medical Center | Springfield | Ohio | 45504 | — |
| Cleveland Clinic Cancer Center Strongsville | Strongsville | Ohio | 44136 | — |
| ProMedica Flower Hospital | Sylvania | Ohio | 43560 | — |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital | Toledo | Ohio | 43606 | — |
| Dayton Physicians LLC - Troy | Troy | Ohio | 45373 | — |
| Upper Valley Medical Center | Troy | Ohio | 45373 | — |
| Saint Joseph Warren Hospital | Warren | Ohio | 44484 | — |
| South Pointe Hospital | Warrensville Heights | Ohio | 44122 | — |
| University of Cincinnati Cancer Center-West Chester | West Chester | Ohio | 45069 | — |
| Cleveland Clinic Wooster Family Health and Surgery Center | Wooster | Ohio | 44691 | — |
| Saint Elizabeth Youngstown Hospital | Youngstown | Ohio | 44501 | — |
| Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma | 73120 | — |
| Saint Charles Health System | Bend | Oregon | 97701 | — |
| Clackamas Radiation Oncology Center | Clackamas | Oregon | 97015 | — |
| Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon | 97015 | — |
| Bay Area Hospital | Coos Bay | Oregon | 97420 | — |
| Providence Newberg Medical Center | Newberg | Oregon | 97132 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | — |
| Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | 18103 | — |
| Saint Luke's Cancer Center - Allentown | Allentown | Pennsylvania | 18104 | — |
| UPMC Altoona | Altoona | Pennsylvania | 16601 | — |
| UPMC-Heritage Valley Health System Beaver | Beaver | Pennsylvania | 15009 | — |
| Saint Luke's University Hospital-Bethlehem Campus | Bethlehem | Pennsylvania | 18015 | — |
| Lehigh Valley Hospital - Muhlenberg | Bethlehem | Pennsylvania | 18017 | — |
| UPMC Hillman Cancer Center at Butler Health System | Butler | Pennsylvania | 16001 | — |
| UPMC Camp Hill | Camp Hill | Pennsylvania | 17011 | — |
| Carlisle Regional Cancer Center | Carlisle | Pennsylvania | 17015 | — |
| Christiana Care Health System-Concord Health Center | Chadds Ford | Pennsylvania | 19317 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| Pocono Medical Center | East Stroudsburg | Pennsylvania | 18301 | — |
| Saint Luke's Hospital-Anderson Campus | Easton | Pennsylvania | 18045 | — |
| UPMC Hillman Cancer Center Erie | Erie | Pennsylvania | 16505 | — |
| UPMC Cancer Center at UPMC Horizon | Farrell | Pennsylvania | 16121 | — |
| UPMC Cancer Centers - Arnold Palmer Pavilion | Greensburg | Pennsylvania | 15601 | — |
| UPMC Pinnacle Cancer Center/Community Osteopathic Campus | Harrisburg | Pennsylvania | 17109 | — |
| Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| IRMC Cancer Center | Indiana | Pennsylvania | 15701 | — |
| Jefferson Hospital | Jefferson Hills | Pennsylvania | 15025 | — |
| UPMC-Johnstown/John P. Murtha Regional Cancer Center | Johnstown | Pennsylvania | 15901 | — |
| Geisinger Medical Oncology-Lewisburg | Lewisburg | Pennsylvania | 17837 | — |
| UPMC Cancer Center at UPMC McKeesport | McKeesport | Pennsylvania | 15132 | — |
| Forbes Hospital | Monroeville | Pennsylvania | 15146 | — |
| UPMC Cancer Center - Monroeville | Monroeville | Pennsylvania | 15146 | — |
| UPMC Hillman Cancer Center - Monroeville | Monroeville | Pennsylvania | 15146 | — |
| UPMC Hillman Cancer Center in Coraopolis | Moon Township | Pennsylvania | 15108 | — |
| UPMC Hillman Cancer Center - Part of Frick Hospital | Mount Pleasant | Pennsylvania | 15666 | — |
| Arnold Palmer Cancer Center Medical Oncology Norwin | N. Huntingdon | Pennsylvania | 15642 | — |
| Allegheny Valley Hospital | Natrona Heights | Pennsylvania | 15065 | — |
| UPMC Hillman Cancer Center - New Castle | New Castle | Pennsylvania | 16105 | — |
| University of Pennsylvania/Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| UPMC-Magee Womens Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC-Saint Margaret | Pittsburgh | Pennsylvania | 15215 | — |
| West Penn Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC-Shadyside Hospital | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC-Passavant Hospital | Pittsburgh | Pennsylvania | 15237 | — |
| UPMC-Saint Clair Hospital Cancer Center | Pittsburgh | Pennsylvania | 15243 | — |
| Pottstown Hospital | Pottstown | Pennsylvania | 19464 | — |
| UPMC Cancer Center at UPMC Northwest | Seneca | Pennsylvania | 16346 | — |
| UPMC Cancer Center-Uniontown | Uniontown | Pennsylvania | 15401 | — |
| UPMC Uniontown Hospital Radiation Oncology | Uniontown | Pennsylvania | 15401 | — |
| UPMC Cancer Center-Washington | Washington | Pennsylvania | 15301 | — |
| UPMC Washington Hospital Radiation Oncology | Washington | Pennsylvania | 15301 | — |
| UPMC West Mifflin-Cancer Center Jefferson | West Mifflin | Pennsylvania | 15122 | — |
| Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| Wexford Health and Wellness Pavilion | Wexford | Pennsylvania | 15090 | — |
| UPMC Memorial | York | Pennsylvania | 17408 | — |
| Rhode Island Hospital at East Greenwich | East Greenwich | Rhode Island | 02818 | — |
| Newport Hospital | Newport | Rhode Island | 02840 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Saint Francis Hospital | Greenville | South Carolina | 29601 | — |
| Saint Francis Cancer Center | Greenville | South Carolina | 29607 | — |
| Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota | 57104 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | 57117-5134 | — |
| Baptist Memorial Hospital and Cancer Center-Collierville | Collierville | Tennessee | 38017 | — |
| Baptist Memorial Hospital and Cancer Center-Memphis | Memphis | Tennessee | 38120 | — |
| Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| Saint Joseph Regional Cancer Center | Bryan | Texas | 77802 | — |
| Parkland Memorial Hospital | Dallas | Texas | 75235 | — |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | — |
| UT Southwestern/Simmons Cancer Center-Fort Worth | Fort Worth | Texas | 76104 | — |
| UT Southwestern Clinical Center at Richardson/Plano | Richardson | Texas | 75080 | — |
| University of Utah Sugarhouse Health Center | Salt Lake City | Utah | 84106 | — |
| Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | 84112 | — |
| Central Vermont Medical Center/National Life Cancer Treatment | Berlin Corners | Vermont | 05602 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| University of Vermont and State Agricultural College | Burlington | Vermont | 05405 | — |
| Dartmouth Cancer Center - North | Saint Johnsbury | Vermont | 05819 | — |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | — |
| Virginia Cancer Institute | Richmond | Virginia | 23229 | — |
| VCU Massey Comprehensive Cancer Center | Richmond | Virginia | 23298 | — |
| VCU Community Memorial Health Center | South Hill | Virginia | 23970 | — |
| Providence Regional Cancer System-Aberdeen | Aberdeen | Washington | 98520 | — |
| Overlake Medical Center | Bellevue | Washington | 98004 | — |
| PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | 98225 | — |
| Highline Medical Center-Main Campus | Burien | Washington | 98166 | — |
| Providence Regional Cancer System-Centralia | Centralia | Washington | 98531 | — |
| Swedish Cancer Institute-Edmonds | Edmonds | Washington | 98026 | — |
| Providence Regional Cancer Partnership | Everett | Washington | 98201 | — |
| Swedish Cancer Institute-Issaquah | Issaquah | Washington | 98029 | — |
| Providence Regional Cancer System-Lacey | Lacey | Washington | 98503 | — |
| PeaceHealth Saint John Medical Center | Longview | Washington | 98632 | — |
| Valley Medical Center | Renton | Washington | 98055 | — |
| Swedish Medical Center-Ballard Campus | Seattle | Washington | 98107 | — |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122 | — |
| PeaceHealth United General Medical Center | Sedro-Woolley | Washington | 98284 | — |
| Saint Joseph Medical Center Hematology and Oncology - Silverdale | Silverdale | Washington | 98383 | — |
| Northwest Medical Specialties PLLC | Tacoma | Washington | 98405 | — |
| PeaceHealth Southwest Medical Center | Vancouver | Washington | 98664 | — |
| Providence Saint Mary Regional Cancer Center | Walla Walla | Washington | 99362 | — |
| North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | Yakima | Washington | 98902 | — |
| United Hospital Center | Bridgeport | West Virginia | 26330 | — |
| Vandalia Health/CAMC Institute for Academic Medicine | Charleston | West Virginia | 25304 | — |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | — |
| Camden Clark Medical Center | Parkersburg | West Virginia | 26101 | — |
| ThedaCare Regional Cancer Center | Appleton | Wisconsin | 54911 | — |
| Duluth Clinic Ashland | Ashland | Wisconsin | 54806 | — |
| Northwest Wisconsin Cancer Center | Ashland | Wisconsin | 54806 | — |
| Aurora Cancer Care-Southern Lakes VLCC | Burlington | Wisconsin | 53105 | — |
| HSHS Sacred Heart Hospital | Eau Claire | Wisconsin | 54701 | — |
| Marshfield Medical Center-EC Cancer Center | Eau Claire | Wisconsin | 54701 | — |
| Aurora Health Center-Fond du Lac | Fond du Lac | Wisconsin | 54937 | — |
| Aurora Health Care Germantown Health Center | Germantown | Wisconsin | 53022 | — |
| Aurora Cancer Care-Grafton | Grafton | Wisconsin | 53024 | — |
| Bellin Memorial Hospital | Green Bay | Wisconsin | 54301 | — |
| Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | 54301 | — |
| Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | 54303 | — |
| Aurora BayCare Medical Center | Green Bay | Wisconsin | 54311 | — |
| Essentia Health-Hayward Clinic | Hayward | Wisconsin | 54843 | — |
| University of Wisconsin Carbone Cancer Center - Johnson Creek | Johnson Creek | Wisconsin | 53038 | — |
| Aurora Cancer Care-Kenosha South | Kenosha | Wisconsin | 53142 | — |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | Wisconsin | 53792 | — |
| Aurora Bay Area Medical Group-Marinette | Marinette | Wisconsin | 54143 | — |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | — |
| Aurora Cancer Care-Milwaukee | Milwaukee | Wisconsin | 53209 | — |
| Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| Aurora Sinai Medical Center | Milwaukee | Wisconsin | 53233 | — |
| Marshfield Medical Center - Minocqua | Minocqua | Wisconsin | 54548 | — |
| Cancer Center of Western Wisconsin | New Richmond | Wisconsin | 54017 | — |
| Vince Lombardi Cancer Clinic - Oshkosh | Oshkosh | Wisconsin | 54904 | — |
| Aurora Cancer Care-Racine | Racine | Wisconsin | 53406 | — |
| Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | 54868 | — |
| Vince Lombardi Cancer Clinic-Sheboygan | Sheboygan | Wisconsin | 53081 | — |
| Essentia Health-Spooner Clinic | Spooner | Wisconsin | 54801 | — |
| Marshfield Medical Center-River Region at Stevens Point | Stevens Point | Wisconsin | 54482 | — |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay | Sturgeon Bay | Wisconsin | 54235-1495 | — |
| Aurora Medical Center in Summit | Summit | Wisconsin | 53066 | — |
| Essentia Health Saint Mary's Hospital - Superior | Superior | Wisconsin | 54880 | — |
| Vince Lombardi Cancer Clinic-Two Rivers | Two Rivers | Wisconsin | 54241 | — |
| Aurora Cancer Care-Milwaukee West | Wauwatosa | Wisconsin | 53226 | — |
| Aurora West Allis Medical Center | West Allis | Wisconsin | 53227 | — |
| Marshfield Medical Center - Weston | Weston | Wisconsin | 54476 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03604991, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 16, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03604991 live on ClinicalTrials.gov.