ClinicalTrials.gov record
A Study to Evaluate Upadacitinib in Adolescents and Adults With Moderate to Severe Atopic Dermatitis (Measure Up 2)
ClinicalTrials.gov ID: NCT03607422
Public ClinicalTrials.gov record NCT03607422. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Upadacitinib in Adolescent and Adult Subjects With Moderate to Severe Atopic Dermatitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to assess the efficacy and safety of upadacitinib for the treatment of adolescent and adult participants with moderate to severe atopic dermatitis (AD) who are candidates for systemic therapy.
Study identification
- NCT ID
- NCT03607422
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 912 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 27, 2018 (Actual)
- Primary completion
- Mar 11, 2021 (Actual)
- Completion
- Nov 11, 2025 (Actual)
- Last update posted
- Jun 2, 2026
2018 – 2025
United States locations
- U.S. sites
- 76
- U.S. states
- 30
- U.S. cities
- 66
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Total Skin and Beauty Derm Ctr /ID# 205129 | Birmingham | Alabama | 35205 | — |
| Medical Dermatology Specialist /ID# 205516 | Phoenix | Arizona | 85006-2722 | — |
| Arizona Research Center, Inc. /ID# 205795 | Phoenix | Arizona | 85053-4061 | — |
| The Dermatology Clinic of Arkansas /ID# 218749 | Bryant | Arkansas | 72022-7514 | — |
| Arkansas Research Trials /ID# 218469 | North Little Rock | Arkansas | 72117 | — |
| Encino Research Center /ID# 207472 | Encino | California | 91436 | — |
| University of California Irvine /ID# 205136 | Irvine | California | 92697-1385 | — |
| Ark Clinical Research /ID# 218193 | Long Beach | California | 90806-2325 | — |
| Keck School of Medicine of USC /ID# 206971 | Los Angeles | California | 90033 | — |
| Wallace Medical Group /ID# 205701 | Los Angeles | California | 90056 | — |
| Child Hosp of Orange County,CA /ID# 205735 | Orange | California | 92868 | — |
| Palmtree Clinical Research Inc. /Id# 206184 | Palm Springs | California | 92262 | — |
| Rady Children's Hospital San Diego /ID# 208244 | San Diego | California | 92123 | — |
| Southern California Derma. Inc /ID# 205734 | Santa Ana | California | 92701 | — |
| Innovative Clinical Research - Lafayette /ID# 208400 | Lafayette | Colorado | 80026 | — |
| New England Research Associates, LLC /ID# 206896 | Bridgeport | Connecticut | 06606-1827 | — |
| Ideal Clinical Research Inc. /ID# 209880 | Aventura | Florida | 33180 | — |
| Skin Care Research, LLC /ID# 207099 | Boca Raton | Florida | 33486-2269 | — |
| Midflorida Clinical Research, Inc. /ID# 213700 | Brandon | Florida | 33511-5335 | — |
| Clinical Research of West Florida, Inc /ID# 206146 | Clearwater | Florida | 33765 | — |
| Revival Research /ID# 208383 | Doral | Florida | 33122-1902 | — |
| Universal Axon Clinical Research /ID# 213703 | Doral | Florida | 33166 | — |
| Lakes Research, LLC /ID# 209156 | Miami | Florida | 33014 | — |
| Miami Dade Medical Research Institute /ID# 209413 | Miami | Florida | 33176 | — |
| Savin Medical Group, LLC /ID# 206902 | Miami Lakes | Florida | 33014-2490 | — |
| Floridian Clinical Research /ID# 207433 | Miami Lakes | Florida | 33016-1842 | — |
| Advanced Research for Health Improvement /ID# 217987 | Naples | Florida | 34102-5430 | — |
| Advanced Research for Health Improvement /ID# 218003 | Naples | Florida | 34102-5430 | — |
| Complete Health Research /ID# 213459 | Ormond Beach | Florida | 32174-6302 | — |
| Precision Clinical Research /ID# 207364 | Sunrise | Florida | 33351-7311 | — |
| Clinical Research Trials of Florida, Inc. /ID# 206840 | Tampa | Florida | 33607 | — |
| ForCare Clinical Research /ID# 205120 | Tampa | Florida | 33613-1244 | — |
| Georgia Pollens Clinical Research Centers, Inc /ID# 218567 | Albany | Georgia | 31707-1282 | — |
| Marietta Dermatology Clinical Research /ID# 210317 | Marietta | Georgia | 30060-1047 | — |
| Agile Clinical Research Trials /ID# 218080 | Sandy Springs | Georgia | 30342 | — |
| Treasure Valley Medical Research /ID# 210298 | Boise | Idaho | 83706 | — |
| Great Lakes Clinical Trials /ID# 205830 | Chicago | Illinois | 60640 | — |
| Ashira Dermatology /ID# 205512 | Gurnee | Illinois | 60031-3393 | — |
| Clinical Investigation Specialists, Inc. /ID# 206898 | Gurnee | Illinois | 60031 | — |
| Northshore University Health System Dermatology Clinical Trials Unit /ID# 205135 | Skokie | Illinois | 60077 | — |
| Raga Clinical Studies, LLC. /ID# 206749 | Crown Point | Indiana | 46307 | — |
| Hutchinson Clinic /ID# 205970 | Hutchinson | Kansas | 67502-1131 | — |
| Continental Clinical Solutions /ID# 210327 | Towson | Maryland | 21204 | — |
| Beacon Clinical Research, LLC /ID# 206894 | Quincy | Massachusetts | 02169 | — |
| David Fivenson, MD, PLC /ID# 206903 | Ann Arbor | Michigan | 48103 | — |
| University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 206895 | Ann Arbor | Michigan | 48109 | — |
| Allergy, Asthma & Immunology Associates, PC /ID# 218169 | Lincoln | Nebraska | 68505-2343 | — |
| Skin Specialists, PC /ID# 205515 | Omaha | Nebraska | 68144 | — |
| Duplicate_Summit Medical Group /ID# 213863 | Clifton | New Jersey | 07012-1647 | — |
| Skin Laser and Surgery Specialists of NY and NJ /ID# 206754 | Hackensack | New Jersey | 07601-1997 | — |
| Care Access Research /ID# 218476 | Hoboken | New Jersey | 07030-2757 | — |
| University of New Mexico School of Medicine /ID# 206756 | Albuquerque | New Mexico | 87131-0001 | — |
| Fordham Dermatology /ID# 218508 | The Bronx | New York | 10458-5046 | — |
| PMG Research of Wilmington LLC /ID# 205968 | Wilmington | North Carolina | 28401 | — |
| University Hospitals Case Medical Center /ID# 206639 | Cleveland | Ohio | 44106 | — |
| Awasty Research Network, LLC /ID# 206748 | Marion | Ohio | 43302-6225 | — |
| Southside Dermatology /ID# 214451 | Tulsa | Oklahoma | 74132 | — |
| Vital Prospects Clinical Research Institute, PC /ID# 205824 | Tulsa | Oklahoma | 74136-7049 | — |
| Cyn3rgy Research /ID# 218064 | Gresham | Oregon | 97030-8316 | — |
| Velocity Clinical Research Hallandale Beach /ID# 207544 | Medford | Oregon | 97504 | — |
| Clinical Research Solutions, LLC /ID# 218416 | Jackson | Tennessee | 38305-2163 | — |
| Stones River Dermatology /ID# 205178 | Murfreesboro | Tennessee | 37129-3194 | — |
| Metroplex Dermatology /ID# 213307 | Arlington | Texas | 76014-3105 | — |
| Bellaire Dermatology /ID# 205470 | Bellaire | Texas | 77401 | — |
| Center for Clinical Studies /ID# 213186 | Cypress | Texas | 77433 | — |
| Dermatology Treatment and Research Center, PA /ID# 205473 | Dallas | Texas | 75230 | — |
| Epiphany Dermatology - Fort Worth /ID# 210073 | Fort Worth | Texas | 76244-6548 | — |
| Styde Research, LLC /ID# 213469 | Lewisville | Texas | 75067 | — |
| Austin Institute for Clinical Research /ID# 206640 | Pflugerville | Texas | 78660 | — |
| Derm Clin Res Ctr San Antonio /ID# 205469 | San Antonio | Texas | 78229 | — |
| EPIC Medical Research /ID# 206382 | Murray | Utah | 84123-5632 | — |
| Aspen Clinical Research /ID# 208399 | Orem | Utah | 84058 | — |
| Timber Lane Allergy & Asthma Research, LLC /ID# 206897 | South Burlington | Vermont | 05403-7204 | — |
| The Education & Research Foundation, Inc. /ID# 206900 | Lynchburg | Virginia | 24501-1403 | — |
| Bellingham Asthma Allergy and Immunology Clinic /ID# 210357 | Bellingham | Washington | 98225-1945 | — |
| Clinical Investigation Specialist, Inc - Kenosha /ID# 215933 | Kenosha | Wisconsin | 53144-1782 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 120 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03607422, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 2, 2026 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03607422 live on ClinicalTrials.gov.