Single Treatment of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-1)
Public ClinicalTrials.gov record NCT03608397. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multi-Center Trial to Evaluate the Efficacy and Safety of a Single Treatment of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-1)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, double-blind, placebo-controlled, parallel group, multi-center trial of two doses of daxibotulinumtoxinA (DAXI) for injection (high-dose; low-dose in adult subjects with isolated (primary) cervical dystonia (CD).
Study identification
- NCT ID
- NCT03608397
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 301 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 20, 2018 (Actual)
- Primary completion
- Dec 3, 2019 (Actual)
- Completion
- Jun 16, 2020 (Actual)
- Last update posted
- Dec 5, 2022
2018 – 2020
United States locations
- U.S. sites
- 44
- U.S. states
- 19
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| HOPE Research Institute | Phoenix | Arizona | 85018 | — |
| Movement Disorders Center of Arizona | Scottsdale | Arizona | 85258-4581 | — |
| The Parkinsons and Movement Disorder Institute | Fountain Valley | California | 92708 | — |
| University of California, Irvine | Irvine | California | 92697 | — |
| Loma Linda University | Loma Linda | California | 92354 | — |
| USC Keck School of Medicine | Los Angeles | California | 90033 | — |
| Care Access Research | Pasadena | California | 91101 | — |
| Sutter Institute for Medical Research | Sacramento | California | 95816 | — |
| Rocky Mountain Movement Disorders Center | Englewood | Colorado | 80113 | — |
| Associated Neurologist, P.C. | Danbury | Connecticut | 06810 | — |
| New England Institute for Clinical Research | Stamford | Connecticut | 06905 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Parkinson's Disease and Movement Disorders Center of Boca Raton | Boca Raton | Florida | 33486 | — |
| Design Neuroscience Center | Doral | Florida | 33172 | — |
| University of Florida Center for Movement Disorders and Neurorestoration | Gainesville | Florida | 32607 | — |
| Infinity Clinical Research | Hollywood | Florida | 33024 | — |
| University of Florida Health Science Center Jacksonville | Jacksonville | Florida | 32209 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Suncoast Neuroscience Associates | St. Petersburg | Florida | 33713-8844 | — |
| USF Parkinson's Disease and Movement Disorders Center | Tampa | Florida | 33613 | — |
| Emory University | Atlanta | Georgia | 30329 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Kansas Institute of Reseach | Overland Park | Kansas | 66211-1358 | — |
| Michigan State University | East Lansing | Michigan | 48824 | — |
| QUEST Research Institute | Farmington | Michigan | 48334 | — |
| Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | 48322 | — |
| St Louis University | St Louis | Missouri | 63105 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Mount Sinai Movement Disorders Center | New York | New York | 10029 | — |
| University of Rochester | Rochester | New York | 14618 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| Wake Forest Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| University of Pennsylvania, Department of Neurology | Philadelphia | Pennsylvania | 19107 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Coastal Neurology | Port Royal | South Carolina | 29935 | — |
| Wesley Neurology Clinic | Cordova | Tennessee | 38018 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Texas Neurology. P.A. | Dallas | Texas | 37232 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Houston Methodist Neurological Institute | Houston | Texas | 77030 | — |
| Central Texas Neurology Consultants | Round Rock | Texas | 78681 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03608397, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 5, 2022 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03608397 live on ClinicalTrials.gov.