Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
Public ClinicalTrials.gov record NCT03616821. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 54-Week, Multicenter, Randomized, Double-blind, Placebo Controlled, Parallel-group Phase 2 Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis (Expedition Lead-in)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The present study (D5272C00001/Legacy #3151-201-008) aims to evaluate the efficacy and safety of brazikumab in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy
Study identification
- NCT ID
- NCT03616821
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 242 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 7, 2018 (Actual)
- Primary completion
- Oct 23, 2023 (Actual)
- Completion
- Oct 23, 2023 (Actual)
- Last update posted
- Jun 23, 2026
2018 – 2023
United States locations
- U.S. sites
- 51
- U.S. states
- 20
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Phoenix | Arizona | 85037 | — |
| Research Site | Tucson | Arizona | 85712 | — |
| Research Site | Little Rock | Arkansas | 72212 | — |
| Research Site | Chula Vista | California | 91911 | — |
| Research Site | Lancaster | California | 93534 | — |
| Research Site | Lincoln | California | 95648 | — |
| Research Site | Mission Hills | California | 91345 | — |
| Research Site | Poway | California | 92064 | — |
| Research Site | Colorado Springs | Colorado | 80907 | — |
| Research Site | Clearwater | Florida | 33756 | — |
| Research Site | Inverness | Florida | 34452 | — |
| Research Site | Kissimmee | Florida | 34741 | — |
| Research Site | Lakeland | Florida | 33813 | — |
| Research Site | Miami | Florida | 33157 | — |
| Research Site | Miami | Florida | 33165 | — |
| Research Site | Miami Lakes | Florida | 33016 | — |
| Research Site | Naples | Florida | 34102 | — |
| Research Site | New Port Richey | Florida | 34653 | — |
| Research Site | Tampa | Florida | 33614 | — |
| Research Site | Tampa | Florida | 33626 | — |
| Research Site | Atlanta | Georgia | 30328 | — |
| Research Site | Gurnee | Illinois | 60031 | — |
| Research Site | Oak Lawn | Illinois | 60453 | — |
| Research Site | Brownsburg | Indiana | 46112 | — |
| Research Site | Evansville | Indiana | 47715 | — |
| Research Site | Shawnee Mission | Kansas | 66226 | — |
| Research Site | Topeka | Kansas | 66606 | — |
| Research Site | Baton Rouge | Louisiana | 70809 | — |
| Research Site | Marrero | Louisiana | 70072 | — |
| Research Site | Shreveport | Louisiana | 71105 | — |
| Research Site | Wyoming | Michigan | 49519 | — |
| Research Site | Biloxi | Mississippi | 39531 | — |
| Research Site | Las Vegas | Nevada | 89106 | — |
| Research Site | Las Vegas | Nevada | 89123 | — |
| Research Site | New York | New York | 10016 | — |
| Research Site | Sunnyside | New York | 11104 | — |
| Research Site | Morehead City | North Carolina | 28557 | — |
| Research Site | Beachwood | Ohio | 44122 | — |
| Research Site | Springfield | Ohio | 45503 | — |
| Research Site | Oklahoma City | Oklahoma | 73112 | — |
| Research Site | Uniontown | Pennsylvania | 15401 | — |
| Research Site | Amarillo | Texas | 79109 | — |
| Research Site | Carrollton | Texas | 75007 | — |
| Research Site | Houston | Texas | 77017 | — |
| Research Site | Houston | Texas | 77058 | — |
| Research Site | Houston | Texas | 77598 | — |
| Research Site | Humble | Texas | 77346 | — |
| Research Site | Pflugerville | Texas | 78660 | — |
| Research Site | San Antonio | Texas | 78229 | — |
| Research Site | San Antonio | Texas | 78258 | — |
| Research Site | North Chesterfield | Virginia | 23236 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 74 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03616821, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 23, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03616821 live on ClinicalTrials.gov.