REPRISE IV: LOTUS Edge Valve System in Intermediate Surgical Risk Subjects
Public ClinicalTrials.gov record NCT03618095. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
REPRISE IV: REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of LOTUS Edge Valve System in IntermediatE Surgical Risk Subjects
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
REPRISE IV: REpositionable Percutaneous Replacement of Stenotic Aortic Valve through Implantation of LOTUS Edge Valve System in IntermediatE Surgical Risk Subjects
Study identification
- NCT ID
- NCT03618095
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 382 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 14, 2019 (Actual)
- Primary completion
- Mar 30, 2021 (Actual)
- Completion
- Mar 31, 2021 (Actual)
- Last update posted
- Dec 27, 2022
2019 – 2021
United States locations
- U.S. sites
- 49
- U.S. states
- 29
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Huntsville Hospital | Huntsville | Alabama | 35801 | — |
| Tucson Medical Center | Tucson | Arizona | 85712 | — |
| Arkansas Heart Hospital | Little Rock | Arkansas | 72211 | — |
| Mills-Peninsula Medical Center - Sutter Health | Burlingame | California | 94010 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| USC Medical Center | Los Angeles | California | 90033 | — |
| Saint Joseph Hospital | Denver | Colorado | 80218 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Medstar Heart and Vascular Institute | Washington D.C. | District of Columbia | 20010 | — |
| JFK Medical Center | Atlantis | Florida | 33462 | — |
| North Florida Regional Medical Center | Gainesville | Florida | 32605 | — |
| AdventHealth Orlando | Orlando | Florida | 32803 | — |
| Piedmont Heart Institute | Atlanta | Georgia | 30309 | — |
| Wellstar Research Institute | Marietta | Georgia | 30060 | — |
| NorthShore University HealthSystem | Evanston | Illinois | 60201 | — |
| Indiana University Health - Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| Via Christi Hospital | Wichita | Kansas | 67214 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Charlton Memorial Hospital - Southcoast Health | Fall River | Massachusetts | 02720 | — |
| Spectrum Health - Grand Rapids | Grand Rapids | Michigan | 49503 | — |
| Cardiac & Vascular Research Center of Northern Michigan | Petoskey | Michigan | 49770 | — |
| Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| St. Cloud Hospital | Saint Cloud | Minnesota | 56303 | — |
| Englewood Hospital | Englewood | New Jersey | 07631 | — |
| Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| NYU Winthrop Hospital | Mineola | New York | 11501 | — |
| NYU Langone Medical Center | New York | New York | 10010 | — |
| Columbia University Medical Center/NewYork Presbyterian Hospital | New York | New York | 10032 | — |
| Novant Health Heart & Vascular Institute - Charlotte | Charlotte | North Carolina | 28204 | — |
| UNC Rex Hospital | Raleigh | North Carolina | 27607 | — |
| The Lindner Center for Research and Education | Cincinnati | Ohio | 45219 | — |
| Providence St. Vincent Medical Center | Portland | Oregon | 97225 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Greenville Memorial Hospital - Prisma Health | Greenville | South Carolina | 29605 | — |
| Centennial Medical Center | Nashville | Tennessee | 37203 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | — |
| Memorial Hermann - Texas Medical Center | Houston | Texas | 77030 | — |
| University of Texas - Memorial Hermann Southwest | Houston | Texas | 77030 | — |
| Baylor Scott & White The Heart Hospital | Plano | Texas | 75093 | — |
| Inova Fairfax Hospital | Annandale | Virginia | 22042 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
| University of Washington | Seattle | Washington | 98195 | — |
| WVU Heart & Vascular Institute | Morgantown | West Virginia | 26506 | — |
| Aurora St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| Froedtert Hospital - Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03618095, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 27, 2022 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03618095 live on ClinicalTrials.gov.