Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure.
Public ClinicalTrials.gov record NCT03619213. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
An International, Double-blind, Randomised, Placebo-Controlled Phase III Study to Evaluate the Effect of Dapagliflozin on Reducing CV Death or Worsening Heart Failure in Patients With Heart Failure With Preserved Ejection Fraction (HFpEF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is an international, multicentre, parallel-group, event-driven, randomised, double-blind, placebo-controlled study in HFpEF patients, evaluating the effect of dapagliflozin 10 mg versus placebo, given once daily in addition to background regional standard of care therapy, including treatments to control co-morbidities, in reducing the composite of CV death or heart failure events.
Study identification
- NCT ID
- NCT03619213
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 6,263 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 40 Years to 130 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 27, 2018 (Actual)
- Primary completion
- Mar 27, 2022 (Actual)
- Completion
- Mar 27, 2022 (Actual)
- Last update posted
- Jul 11, 2023
2018 – 2022
United States locations
- U.S. sites
- 66
- U.S. states
- 32
- U.S. cities
- 60
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Fairhope | Alabama | 36532 | — |
| Research Site | Mobile | Alabama | 36608 | — |
| Research Site | Sheffield | Alabama | 35660 | — |
| Research Site | Tucson | Arizona | 85724 | — |
| Research Site | Little Rock | Arkansas | 72204 | — |
| Research Site | Beverly Hills | California | 90211 | — |
| Research Site | Loma Linda | California | 92357 | — |
| Research Site | Los Angeles | California | 90073 | — |
| Research Site | Stamford | Connecticut | 06905 | — |
| Research Site | Clearwater | Florida | 33756 | — |
| Research Site | Miami | Florida | 33155 | — |
| Research Site | Naples | Florida | 34102 | — |
| Research Site | Ocala | Florida | 34471 | — |
| Research Site | Ormond Beach | Florida | 32174 | — |
| Research Site | Port Charlotte | Florida | 33952 | — |
| Research Site | Saint Augustine | Florida | 32086 | — |
| Research Site | Atlanta | Georgia | 30303 | — |
| Research Site | Chicago | Illinois | 60612 | — |
| Research Site | Chicago | Illinois | 60637 | — |
| Research Site | Gurnee | Illinois | 60031 | — |
| Research Site | Anderson | Indiana | 46011 | — |
| Research Site | Munster | Indiana | 46321 | — |
| Research Site | Louisville | Kentucky | 40202 | — |
| Research Site | Hammond | Louisiana | 70403 | — |
| Research Site | Houma | Louisiana | 70360 | — |
| Research Site | Monroe | Louisiana | 71201 | — |
| Research Site | Boston | Massachusetts | 02114 | — |
| Research Site | Boston | Massachusetts | 02115 | — |
| Research Site | Bay City | Michigan | 48708 | — |
| Research Site | Flint | Michigan | 48504 | — |
| Research Site | Flint | Michigan | 48532 | — |
| Research Site | Minneapolis | Minnesota | 55417 | — |
| Research Site | Rochester | Minnesota | 55905 | — |
| Research Site | Saint Paul | Minnesota | 55102 | — |
| Research Site | Kansas City | Missouri | 64111 | — |
| Research Site | Kansas City | Missouri | 64128 | — |
| Research Site | St Louis | Missouri | 63136 | — |
| Research Site | Great Falls | Montana | 59405 | — |
| Research Site | Las Vegas | Nevada | 89106 | — |
| Research Site | Lebanon | New Hampshire | 03756 | — |
| Research Site | Bridgewater | New Jersey | 08807 | — |
| Research Site | Buffalo | New York | 14215 | — |
| Research Site | New York | New York | 10001 | — |
| Research Site | New York | New York | 10021 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | Charlotte | North Carolina | 28277 | — |
| Research Site | Greensboro | North Carolina | 27405 | — |
| Research Site | Wilmington | North Carolina | 28401 | — |
| Research Site | Oklahoma City | Oklahoma | 73134 | — |
| Research Site | Altoona | Pennsylvania | 16601 | — |
| Research Site | Doylestown | Pennsylvania | 18901 | — |
| Research Site | Providence | Rhode Island | 02908 | — |
| Research Site | Charleston | South Carolina | 29425 | — |
| Research Site | Rapid City | South Dakota | 57701 | — |
| Research Site | Jackson | Tennessee | 38301 | — |
| Research Site | Nashville | Tennessee | 37212 | — |
| Research Site | Tullahoma | Tennessee | 37388 | — |
| Research Site | Beaumont | Texas | 77701 | — |
| Research Site | Humble | Texas | 77338 | — |
| Research Site | Sherman | Texas | 75092 | — |
| Research Site | Burlington | Vermont | 05401 | — |
| Research Site | Falls Church | Virginia | 22042 | — |
| Research Site | Leesburg | Virginia | 20176 | — |
| Research Site | Morgantown | West Virginia | 26506 | — |
| Research Site | Madison | Wisconsin | 53705 | — |
| Research Site | Milwaukee | Wisconsin | 53295 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 282 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03619213, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 11, 2023 · Synced Nov 5, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03619213 live on ClinicalTrials.gov.