Conditioning SCID Infants Diagnosed Early
Public ClinicalTrials.gov record NCT03619551. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Trial of Low Versus Moderate Exposure Busulfan for Infants With Severe Combined Immunodeficiency (SCID) Receiving TCRαβ+/CD19+ Depleted Transplantation: A Phase II Study by the Primary Immune Deficiency Treatment Consortium (PIDTC) and Pediatric Blood and Marrow Transplant Consortium (PBMTC)
Study identification
- NCT ID
- NCT03619551
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Center for International Blood and Marrow Transplant Research
- Network
- Enrollment
- 56 participants
Conditions and interventions
Conditions
Interventions
- Busulfan Drug
- Cell processing for TCRαβ+/CD19+ depletion Device
Drug · Device
Eligibility (public fields only)
- Age range
- 0 Years to 2 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 21, 2018
- Primary completion
- Nov 30, 2027
- Completion
- Nov 30, 2028
- Last update posted
- Jul 8, 2026
2018 – 2028
United States locations
- U.S. sites
- 40
- U.S. states
- 27
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Univeristy of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Mayo Clinic Arizona and Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | — |
| UCLA Center for Health Sciences | Los Angeles | California | 90095 | — |
| Rady Children's Hospital, San Diego | San Diego | California | 92123 | — |
| University of California San Francisco Medical Center - Peds | San Francisco | California | 94143 | — |
| University of Colorado - Children's Hospital | Aurora | Colorado | 80045 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010 | — |
| Shands HealthCare & University of Florida | Gainesville | Florida | 32610 | — |
| University of Miami/Jackson Memorial Hospital | Miami | Florida | 33136 | — |
| All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| Children's Healthcare of Atlanta at Egleston | Atlanta | Georgia | 30329 | — |
| Comer Children's Hospital/University of Chicago Medicine | Chicago | Illinois | 60637 | — |
| Indiana University Hospital/Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | — |
| Children's Hospital / LSUHSC | New Orleans | Louisiana | 70118 | — |
| Dana Farber Cancer Institute - Peds | Boston | Massachusetts | 02115 | — |
| The University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Helen DeVos Children's | Grand Rapids | Michigan | 49503 | — |
| University of Minnesota Blood and Marrow Transplant Program - Pediatrics | Minneapolis | Minnesota | 55455 | — |
| The Children's Mercy Hospitals and Clinics | Kansas City | Missouri | 64108 | — |
| Cardinal Glennon Children's Medical Center | St Louis | Missouri | 63104 | — |
| Nebraska Medicine | Omaha | Nebraska | 68198 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Morgan Stanley Children's Hospital of New York-Presbyterian - Columbia University Medical Center | New York | New York | 10032 | — |
| Memorial Sloan Kettering Cancer Center - Peds | New York | New York | 10065 | — |
| Cohen Children's Medical Center | Queens | New York | 11040 | — |
| Westchester Medical Center | Valhalla | New York | 10595 | — |
| Levine Children's Hospital | Charlotte | North Carolina | 28203 | — |
| Duke University Medical Center; Pediatric Blood and Marrow Transplant | Durham | North Carolina | 27705 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| Oregon Health and Science University | Portland | Oregon | 97239-3098 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Children's Medical Center Dallas | Dallas | Texas | 75235 | — |
| Utah Blood and Marrow Transplant Program-Peds | Salt Lake City | Utah | 84112 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
| University of Wisconsin Hospital and Clinics | Madison | Wisconsin | 53792 | — |
| Children's Hospital of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03619551, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 8, 2026 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03619551 live on ClinicalTrials.gov.