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Completed Phase 3 Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Interchangeability of V114 and Prevnar 13™ in Healthy Infants (V114-027/PNEU-DIRECTION)

ClinicalTrials.gov ID: NCT03620162

Public ClinicalTrials.gov record NCT03620162. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 11:45 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multicenter, Randomized, Double-blind Study to Evaluate the Interchangeability of V114 and Prevnar 13™ With Respect to Safety, Tolerability, and Immunogenicity in Healthy Infants (PNEU-DIRECTION)

Study identification

NCT ID
NCT03620162
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
900 participants

Conditions and interventions

Interventions

  • Prevnar 13™ Biological
  • V114 Biological
  • RotaTeq™ Biological
  • Pentacel™ Biological
  • RECOMBIVAX HB™ Biological
  • HIBERIX™ Biological
  • M-M-R™ II Biological
  • VARIVAX™ Biological

Biological

Eligibility (public fields only)

Age range
42 Days to 90 Days
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 17, 2018
Primary completion
Dec 13, 2020
Completion
Dec 13, 2020
Last update posted
Jan 16, 2023

2018 – 2020

United States locations

U.S. sites
22
U.S. states
14
U.S. cities
19
Facility City State ZIP Site status
Alabama Clinical Therapeutics ( Site 0015) Birmingham Alabama 35205
Southeastern Pediatric Associates, P.A. ( Site 0002) Dothan Alabama 36305
Children's Clinic of Jonesboro, PA ( Site 0022) Jonesboro Arkansas 72401
Davita Medical Group ( Site 0012) Colorado Springs Colorado 80922
Suncoast Research Associates, LLC ( Site 0035) Miami Florida 33184
Kentucky Pediatric/Adult Research Inc ( Site 0011) Bardstown Kentucky 40004
Pediatric Associates of Fall River ( Site 0021) Fall River Massachusetts 02721
Midwest Children's Health Research Institute, LLC ( Site 0024) Lincoln Nebraska 68504
Midwest Children's Health Research Institute, LLC ( Site 0003) Lincoln Nebraska 68505
Midwest Children's Health Research Institute, LLC ( Site 0004) Lincoln Nebraska 68516
Midwest Children's Health Research Institute, LLC ( Site 0001) Lincoln Nebraska 68522
Summerwood Pediatrics ( Site 0009) Liverpool New York 13088
University of Rochester Medical Center ( Site 0029) Rochester New York 14642
SUNY Upstate Medical University ( Site 0008) Syracuse New York 13202
Piedmont Healthcare, PA ( Site 0025) Statesville North Carolina 28625
Coastal Pediatric Research ( Site 0006) Charleston South Carolina 29414
Parkside Pediatric ( Site 0007) Greenville South Carolina 29607
Holston Medical Group ( Site 0018) Kingsport Tennessee 37660
Ventavia Research Group LLC ( Site 0017) Fort Worth Texas 76104
University of Texas Medical Branch ( Site 0023) Galveston Texas 77555
Wasatch Pediatrics-Cottonwood Office ( Site 0014) Murray Utah 84107
Multicare ( Site 0019) Spokane Washington 99202

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03620162, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 16, 2023 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03620162 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →