Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled Gout
Public ClinicalTrials.gov record NCT03635957. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Efficacy and Safety Study of Methotrexate to Increase Response Rates in Patients With Uncontrolled Gout Receiving KRYSTEXXA® (Pegloticase) (MIRROR Open-Label [OL])
Study identification
- NCT ID
- NCT03635957
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 14 participants
Conditions and interventions
Conditions
Interventions
- Pegloticase Biological
- Methotrexate (MTX) Drug
- Standard Gout Flare Prophylaxis Drug
- Infusion Reaction (IR) Prophylaxis Drug
- Folic Acid Dietary Supplement
Biological · Drug · Dietary Supplement
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 25, 2018
- Primary completion
- Oct 22, 2019
- Completion
- Oct 25, 2020
- Last update posted
- Jun 25, 2024
2018 – 2020
United States locations
- U.S. sites
- 6
- U.S. states
- 4
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Orthopedic Physicians Alaska | Anchorage | Alaska | 99508 | — |
| Arizona Arthritis & Rheumatology -West Valley | Glendale | Arizona | 85306 | — |
| Arizona Arthritis & Rheumatology -East Valley | Mesa | Arizona | 85210 | — |
| Avail Clinical Research | DeLand | Florida | 32720 | — |
| Western Washington Arthritis Clinic | Bothell | Washington | 98021 | — |
| Arthritis Northwest PLLC | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03635957, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 25, 2024 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03635957 live on ClinicalTrials.gov.