A Study of Aducanumab in Participants With Mild Cognitive Impairment Due to Alzheimer's Disease or With Mild Alzheimer's Disease Dementia to Evaluate the Safety of Continued Dosing in Participants With Asymptomatic Amyloid-Related Imaging Abnormalities
Public ClinicalTrials.gov record NCT03639987. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Parallel-Group, Double-Blind, Controlled Study of Aducanumab (BIIB037) in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease or With Mild Alzheimer's Disease Dementia to Evaluate the Safety of Continued Dosing in Subjects With Asymptomatic Amyloid-Related Imaging Abnormalities
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of the study is to assess the safety impact of continuing aducanumab dosing in asymptomatic Amyloid-related Imaging Abnormalities (ARIA) in participants with mild cognitive impairment (MCI) due to Alzheimer's disease (AD) or with mild AD dementia. The secondary objective of the study is to characterize ARIA, from both the imaging and the clinical perspective and to characterize the safety, tolerability, pharmacokinetics (PK), and immunogenicity of aducanumab.
Study identification
- NCT ID
- NCT03639987
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 52 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 20, 2018 (Actual)
- Primary completion
- Jul 30, 2019 (Actual)
- Completion
- Jul 30, 2019 (Actual)
- Last update posted
- Sep 16, 2021
2018 – 2019
United States locations
- U.S. sites
- 22
- U.S. states
- 12
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Alzheimer's Institute | Phoenix | Arizona | 85006 | — |
| Center for Neurosciences | Tucson | Arizona | 85718 | — |
| Neurology Center of North Orange County | Fullerton | California | 92835 | — |
| Pacific Neuroscience Medical Group | Oxnard | California | 93030 | — |
| Pacific Research Network, Inc | San Diego | California | 92103 | — |
| California Neuroscience Research Medical Group Inc. | Sherman Oaks | California | 91403 | — |
| JEM Research Institute | Atlantis | Florida | 33462 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Neuropsychiatric Research Center of Southwest Florida | Fort Myers | Florida | 33912 | — |
| Bioclinica Orlando | Orlando | Florida | 32806 | — |
| Bioclinica Orlando | The Villages | Florida | 32162 | — |
| Medical Research Health and Education Foundation, Inc | Columbus | Georgia | 31909 | — |
| Josephson, Wallack, Munshower Neurology, P.C. | Indianapolis | Indiana | 46256 | — |
| Las Vegas Medical Research | Las Vegas | Nevada | 89113 | — |
| Advanced Memory Research Institute of NJ, PC | Toms River | New Jersey | 08755 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Neurology Clinic, PC | Cordova | Tennessee | 38108 | — |
| Senior Adult Specialty Research | Austin | Texas | 78757 | — |
| Baylor College Of Medicine | Houston | Texas | 77030 | — |
| Clinical Trial Network | Houston | Texas | 77074 | — |
| National Clinical Research Inc.-Richmond | Richmond | Virginia | 23294 | — |
| Kingfisher Cooperative, LLC | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03639987, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 16, 2021 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03639987 live on ClinicalTrials.gov.