Efficacy and Safety of KD025 in Subjects With cGVHD After At Least 2 Prior Lines of Systemic Therapy
Public ClinicalTrials.gov record NCT03640481. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of KD025 in Subjects With Chronic Graft Versus Host Disease (cGVHD) After At Least 2 Prior Lines of Systemic Therapy (The ROCKstar Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2, randomized, multicenter study to evaluate the efficacy and safety of KD025 in subjects with Chronic Graft Versus Host Disease (cGVHD) after at least 2 prior lines of systemic therapy
Study identification
- NCT ID
- NCT03640481
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 159 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 11, 2018 (Actual)
- Primary completion
- Dec 11, 2023 (Actual)
- Completion
- Dec 11, 2023 (Actual)
- Last update posted
- Dec 12, 2024
2018 – 2023
United States locations
- U.S. sites
- 35
- U.S. states
- 22
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Childrens Hospital Site Number : 154 | Phoenix | Arizona | 85016 | — |
| University of Arizona - Cancer Center Site Number : 122 | Tucson | Arizona | 85724 | — |
| City of Hope Medical Center Site Number : 050 | Duarte | California | 91010 | — |
| University of California, Los Angeles (UCLA) - Medical Center Site Number : 104 | Los Angeles | California | 90059 | — |
| University of California, San Francisco (UCSF) - Helen Diller Family Comprehensive Cancer Center Site Number : 058 | San Francisco | California | 94143 | — |
| Stanford Cancer Center Site Number : 108 | Stanford | California | 94305 | — |
| Colorado Blood Cancer Institute Site Number : 098 | Denver | Colorado | 80218 | — |
| University of Miami - Sylvester Cancer Center Site Number : 097 | Miami | Florida | 33136 | — |
| Moffitt Site Number : 102 | Tampa | Florida | 33612 | — |
| Emory University School of Medicine Site Number : 100 | Atlanta | Georgia | 30322 | — |
| Augusta University Medical Center Site Number : 093 | Augusta | Georgia | 30912 | — |
| University of Illinois at Chicago Site Number : 139 | Chicago | Illinois | 60612 | — |
| University of Iowa Site Number : 126 | Iowa City | Iowa | 52242 | — |
| University of Kansas Cancer Center Site Number : 105 | Fairway | Kansas | 66205 | — |
| Center for Cancer Research National Cancer Institute Site Number : 107 | Bethesda | Maryland | 20892-1203 | — |
| Massachusetts General Hospital Site Number : 002 | Boston | Massachusetts | 02114 | — |
| Dana-Farber Cancer Institute Site Number : 004 | Boston | Massachusetts | 02215 | — |
| CS Mott Children's Hospital Site Number : 157 | Ann Arbor | Michigan | 48109-5718 | — |
| Barbara Ann Karmanos Cancer Institute-4100 John R St Site Number : 094 | Detroit | Michigan | 48201 | — |
| University of Minnesota Site Number : 051 | Minneapolis | Minnesota | 55455 | — |
| Washington University School of Medicine Site Number : 125 | St Louis | Missouri | 63110 | — |
| University of Rochester Site Number : 106 | Rochester | New York | 14642 | — |
| Wake Forest Site Number : 123 | Winston-Salem | North Carolina | 27157 | — |
| The Cleveland Clinic Foundation Site Number : 041 | Cleveland | Ohio | 44195 | — |
| James Cancer Hospital & Wexner Medical Center at the Ohio State University Comprehensive Cancer Center Site Number : 103 | Columbus | Ohio | 43210 | — |
| Oregon Health & Science University (OHSU) Site Number : 095 | Portland | Oregon | 97239-3098 | — |
| University of Pittsburgh Medical Center (UPMC) - Hillman Cancer Center Site Number : 132 | Pittsburgh | Pennsylvania | 15232 | — |
| Sarah Cannon and HCA Research Institute Site Number : 007 | Nashville | Tennessee | 37203 | — |
| Vanderbilt University Medical Center Site Number : 063 | Nashville | Tennessee | 37232-6868 | — |
| South Austin Medical Center Site Number : 091 | Austin | Texas | 78704 | — |
| MD Anderson Cancer Center Site Number : 057 | Houston | Texas | 77030-4009 | — |
| Texas Transplant Institute Site Number : 079 | San Antonio | Texas | 78229 | — |
| Fred Hutchinson Cancer Research Center Site Number : 052 | Seattle | Washington | 98109 | — |
| University of Wisconsin - Carbone Cancer Center Site Number : 135 | Madison | Wisconsin | 53792 | — |
| Froedtert Hospital and the Medical College of Wisconsin Site Number : 101 | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03640481, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 12, 2024 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03640481 live on ClinicalTrials.gov.