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Terminated Phase 3 Interventional Results available

Niemann-Pick Type C Treatment With Adrabetadex for Symptoms of Brain and Nervous System

ClinicalTrials.gov ID: NCT03643562

Public ClinicalTrials.gov record NCT03643562. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 4:44 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open-label Evaluation of Adrabetadex in Patients With Neurologic Manifestations of Niemann-Pick Type C Disease (NPC)

Study identification

NCT ID
NCT03643562
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Mandos LLC
Industry
Enrollment
27 participants

Conditions and interventions

Interventions

  • Adrabetadex Drug

Drug

Eligibility (public fields only)

Age range
4 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 17, 2018
Primary completion
Nov 1, 2021
Completion
Nov 1, 2021
Last update posted
Jan 16, 2024

2018 – 2021

United States locations

U.S. sites
17
U.S. states
14
U.S. cities
16
Facility City State ZIP Site status
University of Arkansas System Little Rock Arkansas 72205
Loma Linda University Health System Loma Linda California 92354
Children's Hospital Los Angeles Los Angeles California 90027
Children's Hospital of Orange County Orange California 92868
Children's Hospital Colorado Aurora Colorado 80045
Children's National Hospital Washington D.C. District of Columbia 20010
Rare Disease Research, LLC Atlanta Georgia 30318
Rush University Medical Center Chicago Illinois 60612
Gillette Children's Specialty Healthcare Saint Paul Minnesota 55101
Children's Specialty Center of Nevada Las Vegas Nevada 89109
NYU Langone Medical Center New York New York 10017
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
Oregon Health & Science University Portland Oregon 97239
The Children's Hospital at TriStar Centennial Nashville Tennessee 37203
Vanderbilt University Medical Center Nashville Tennessee 37232
Dell Children's Medical Center of Central Texas Austin Texas 78723
Carilion Medical Center, Carilion Clinic Roanoke Virginia 24014

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03643562, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 16, 2024 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03643562 live on ClinicalTrials.gov.

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