A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Upadacitinib in Pediatric Participants With Severe Atopic Dermatitis
Public ClinicalTrials.gov record NCT03646604. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label Multiple Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Upadacitinib in Pediatric Subjects With Severe Atopic Dermatitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to evaluate the safety, pharmacokinetics and tolerability of multiple doses of upadacitinib in pediatric participants with severe atopic dermatitis and to evaluate palatability of upadacitinib oral solution in pediatric participants.
Study identification
- NCT ID
- NCT03646604
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 35 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 2 Years to 12 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2019 (Actual)
- Primary completion
- Aug 29, 2024 (Actual)
- Completion
- Aug 29, 2024 (Actual)
- Last update posted
- Feb 10, 2025
2019 – 2024
United States locations
- U.S. sites
- 15
- U.S. states
- 12
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Beach Pediatrics /ID# 207834 | Huntington Beach | California | 92647-6818 | — |
| Children's Hospital Los Angeles /ID# 206042 | Los Angeles | California | 90027 | — |
| Pediatric Skin Research, LLC /ID# 213468 | Coral Gables | Florida | 33146-1837 | — |
| Rybear, Inc /ID# 231801 | Fort Lauderdale | Florida | 33316-1952 | — |
| IACT Health-Columbus /ID# 216370 | Columbus | Georgia | 31904-8946 | — |
| Northwestern University Feinberg School of Medicine /ID# 206224 | Chicago | Illinois | 60611-2927 | — |
| Dawes Fretzin, LLC /ID# 214958 | Indianapolis | Indiana | 46256 | — |
| Duplicate_Washington University of St. Louis /ID# 206972 | St Louis | Missouri | 63141-6399 | — |
| University of New Mexico School of Medicine /ID# 206757 | Albuquerque | New Mexico | 87131-0001 | — |
| Cincinnati Children's Hospital /ID# 207071 | Cincinnati | Ohio | 45229 | — |
| Oregon Medical Research Center /ID# 206226 | Portland | Oregon | 97239 | — |
| Penn State University and Milton S. Hershey Medical Center /ID# 207096 | Hershey | Pennsylvania | 17033-2360 | — |
| Paddington Testing Co., Inc. /ID# 207079 | Philadelphia | Pennsylvania | 19103 | — |
| Arlington Research Center, Inc /ID# 222901 | Arlington | Texas | 76011 | — |
| West Virginia University Hospitals /ID# 206792 | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03646604, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 10, 2025 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03646604 live on ClinicalTrials.gov.