XEN-45 Gel Stent Versus Trabeculectomy in Glaucoma: Gold-Standard Pathway Study (GPS)
Public ClinicalTrials.gov record NCT03654885. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the safety and efficacy of XEN-45 to trabeculectomy in participants with open angle glaucoma refractory to topical medical therapy.
Study identification
- NCT ID
- NCT03654885
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 158 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 1, 2018 (Actual)
- Primary completion
- May 13, 2021 (Actual)
- Completion
- May 13, 2021 (Actual)
- Last update posted
- Jul 21, 2022
2018 – 2021
United States locations
- U.S. sites
- 35
- U.S. states
- 23
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Vold Vision /ID# 233677 | Fayetteville | Arkansas | 72704 | — |
| Retina Institute of California /ID# 233692 | Arcadia | California | 91007 | — |
| Angeles Eye Institute /ID# 233632 | Culver City | California | 90232 | — |
| Cha Medical Group Pc /Id# 233649 | Los Angeles | California | 90027 | — |
| Grutzmacher Lewis and Sierra Inc. /ID# 233654 | Sacramento | California | 95815 | — |
| University of Colorado Denver /ID# 233676 | Denver | Colorado | 80291-0238 | — |
| Howard University Hospital /ID# 233615 | Washington D.C. | District of Columbia | 20060 | — |
| Eye Surgery Associates /ID# 233638 | Hollywood | Florida | 33020 | — |
| Specialty Retina Center /ID# 233628 | Weston | Florida | 33326 | — |
| Georgia Eye Partners /ID# 233655 | Atlanta | Georgia | 30342 | — |
| Coastal Research Associates /ID# 233575 | Roswell | Georgia | 30076 | — |
| Tyrie Lee Jenkins MD Inc. /ID# 233674 | Honolulu | Hawaii | 96814 | — |
| Illinois Eye Center /ID# 233631 | Peoria | Illinois | 61615 | — |
| Stiles Eyecare Excellence /ID# 233583 | Overland Park | Kansas | 66213 | — |
| Advanced Glaucoma Specialists /ID# 233690 | Reading | Massachusetts | 01867 | — |
| Kellogg Eye Center University of Michigan health system /ID# 233651 | Ann Arbor | Michigan | 48105 | — |
| Mayo Clinic Jacksonville /ID# 233634 | Saint Paul | Minnesota | 55108 | — |
| Washington University in St. Louis /ID# 233599 | St Louis | Missouri | 63110 | — |
| Glaucoma associates/consultants of the capital region /ID# 233695 | Slingerlands | New York | 12159 | — |
| Carolina Eye Associates /ID# 233656 | Southern Pines | North Carolina | 28387 | — |
| Eye Care Associates Inc /ID# 233636 | Youngstown | Ohio | 44502 | — |
| Dean McGee Eye Institute /ID# 233595 | Oklahoma City | Oklahoma | 73104 | — |
| Ludwick Eye Center /ID# 233691 | Chambersburg | Pennsylvania | 17201 | — |
| Kremer Eye Center /Id# 233642 | King of Prussia | Pennsylvania | 19406 | — |
| Wills Eye Institute /ID# 233645 | Philadelphia | Pennsylvania | 19107 | — |
| university of Pittsburgh /ID# 233622 | Pittsburgh | Pennsylvania | 15213 | — |
| Carolinas Centers for Sight,PC /ID# 233606 | Florence | South Carolina | 29501 | — |
| Nashville Vision Associates /ID# 233644 | Nashville | Tennessee | 37205 | — |
| Glaucoma Associates of Texas /ID# 233587 | Dallas | Texas | 75231 | — |
| El Paso Eye Surgeons, P.A. /ID# 233584 | El Paso | Texas | 79902 | — |
| Houston Eye Associates /ID# 233621 | Houston | Texas | 77025 | — |
| Baylor College of Medicine - Baylor Medical Center /ID# 233612 | Houston | Texas | 77030-3411 | — |
| Vistar Eye Center /ID# 233652 | Roanoke | Virginia | 24011 | — |
| SSM Health Dean Medical Group /ID# 233624 | Madison | Wisconsin | 53715 | — |
| The Eye Centers of Racine and Kenosha LTD /ID# 233657 | Racine | Wisconsin | 53405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03654885, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 21, 2022 · Synced Nov 10, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03654885 live on ClinicalTrials.gov.