A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma
Public ClinicalTrials.gov record NCT03656536. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Open-Label, Randomized, Active-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Gemcitabine Plus Cisplatin Chemotherapy in First-Line Treatment of Participants With Unresectable or Metastatic Cholangiocarcinoma With FGFR2 Rearrangement (FIGHT-302)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or metastatic cholangiocarcinoma with FGFR2 rearrangement.
Study identification
- NCT ID
- NCT03656536
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 167 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 3, 2019 (Actual)
- Primary completion
- Jul 7, 2025 (Actual)
- Completion
- Jul 7, 2025 (Actual)
- Last update posted
- Aug 11, 2026
2019 – 2025
United States locations
- U.S. sites
- 36
- U.S. states
- 26
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Arizona | Phoenix | Arizona | 85054 | — |
| Marin Cancer Care | Greenbrae | California | 94904 | — |
| UC Irvine Medical Center | Orange | California | 92868-3201 | — |
| Georgetown University-Lombardi Comprehensive Cancer Center | Washington D.C. | District of Columbia | 20007 | — |
| Mayo Clinic-Florida | Jacksonville | Florida | 32224 | — |
| Mount Sinai Medical Center Comprehensive Cancer Center | Miami Beach | Florida | 33140 | — |
| Winship Cancer Institute of Emory University | Atlanta | Georgia | 30322 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637-1447 | — |
| Parkview Research Center | Fort Wayne | Indiana | 46845 | — |
| University of Iowa Hospital and Clinics | Iowa City | Iowa | 52242 | — |
| The University of Kansas Cancer Center | Westwood | Kansas | 66205 | — |
| Ochsner Clinic Foundation Ocf Ochsner Cancer Institute Oci | New Orleans | Louisiana | 70121 | — |
| Johns Hopkins Oncology Center | Baltimore | Maryland | 21287 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Barbara Ann Karmanos Cancer Hospital | Detroit | Michigan | 48201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Karmanos Cancer Institute | Farmington Hills | Michigan | 48334 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Comprehensive Cancer Centers of Nevada-Twain | Las Vegas | Nevada | 89169 | — |
| Summit Medical Group | Florham Park | New Jersey | 07932 | — |
| Icahn School of Medicine At Mount Sinai | New York | New York | 10029 | — |
| White Plains Hospital | White Plains | New York | 10601 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Providence Portland Med. Ctr | Portland | Oregon | 97213 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Greenville Hospital System University Medical Center Institute For Translational Oncology Research | Greenville | South Carolina | 29605 | — |
| Baylor Scott and White Research Institute | Dallas | Texas | 75246 | — |
| Houston Methodist Research Institute | Houston | Texas | 77030 | — |
| Riverside Regional Medical Center | Newport News | Virginia | 23601 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23229 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| West Virginia University Cancer Institute | Morgantown | West Virginia | 26506 | — |
| Aurora Research Institute | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 179 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03656536, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 11, 2026 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03656536 live on ClinicalTrials.gov.