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Completed Phase 1 Interventional

Grapiprant and Pembrolizumab in Patients With Advanced or Progressive MSS Colorectal Cancer

ClinicalTrials.gov ID: NCT03658772

Public ClinicalTrials.gov record NCT03658772. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 9:36 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label, Single-arm, Phase 1b Study to Evaluate the Safety and Efficacy of Grapiprant (ARY-007) in Combination With Pembolizumab in Patients With Advanced or Progressive Microsatellite Stable (MSS) Colorectal Cancer (CRC)

Study identification

NCT ID
NCT03658772
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Arrys Therapeutics
Industry
Enrollment
54 participants

Conditions and interventions

Interventions

  • grapiprant Drug
  • grapiprant and pembrolizumab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 19, 2018
Primary completion
Mar 6, 2023
Completion
Mar 6, 2023
Last update posted
Oct 23, 2023

2018 – 2023

United States locations

U.S. sites
4
U.S. states
4
U.S. cities
4
Facility City State ZIP Site status
Mayo Clinic Cancer Center - Scottsdale Phoenix Arizona 85054
University of Colorado Denver-Anschutz Medical Campus Aurora Colorado 80045
Sarah Cannon Research Institute, LLC (SCRI) Nashville Tennessee 37203
New Experimental Therapeutics of San Antonio-NEXT Oncology San Antonio Texas 78240

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03658772, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 23, 2023 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03658772 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →