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Terminated Phase 1 Interventional Results available

Safety and Antitumor Activity Study of Loncastuximab Tesirine and Durvalumab in Diffuse Large B-Cell, Mantle Cell, or Follicular Lymphoma

ClinicalTrials.gov ID: NCT03685344

Public ClinicalTrials.gov record NCT03685344. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 12:40 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Open-Label Study to Evaluate the Safety and Antitumor Activity of Loncastuximab Tesirine and Durvalumab in Patients With Advanced Diffuse Large B-Cell Lymphoma, Mantle Cell Lymphoma, or Follicular Lymphoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this phase 1 study is to evaluate the safety and anti-tumor activity of Loncastuximab Tesirine (ADCT-402) and Durvalumab in participants with Advanced Diffuse Large B-Cell Lymphoma, Mantle Cell Lymphoma, or Follicular Lymphoma

Study identification

NCT ID
NCT03685344
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
ADC Therapeutics S.A.
Industry
Enrollment
13 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 4, 2019 (Actual)
Primary completion
Oct 27, 2020 (Actual)
Completion
Oct 27, 2020 (Actual)
Last update posted
Oct 26, 2021

2019 – 2020

United States locations

U.S. sites
9
U.S. states
6
U.S. cities
9
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294 —
UCH-MHS Memorial Hospital Centeral Colorado Springs Colorado 80909 —
University of Florida Health Shands Cancer Hospital Gainesville Florida 32603 —
University of Miami - Sylvester Comprehensive Cancer Center Miami Florida 33136 —
Rutgers Cancer Institute of New Jersey New Brunswick New Jersey 08901 —
Icahm School of Medicine at Mount Sinai New York New York 10029 —
Baylor University Medical Center Dallas Texas 75246 —
Joe Arrington Cancer Research and Treatment Center Lubbock Texas 79410 —
Baylor Scott & White Medical Center - Temple Temple Texas 76508 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03685344, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 26, 2021 · Synced Oct 20, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03685344 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →