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Completed Phase 3 Interventional Results available

Evaluation of VX 445/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age

ClinicalTrials.gov ID: NCT03691779

Public ClinicalTrials.gov record NCT03691779. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:36 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Study Evaluating the Pharmacokinetics, Safety, and Tolerability of VX-445/TEZ/IVA Triple Combination Therapy in Cystic Fibrosis Subjects 6 Through 11 Years of Age

Study identification

NCT ID
NCT03691779
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Vertex Pharmaceuticals Incorporated
Industry
Enrollment
71 participants

Conditions and interventions

Interventions

  • ELX/TEZ/IVA Drug
  • IVA Drug

Drug

Eligibility (public fields only)

Age range
6 Years to 11 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 1, 2018
Primary completion
Aug 6, 2020
Completion
Aug 6, 2020
Last update posted
Oct 21, 2021

2018 – 2020

United States locations

U.S. sites
13
U.S. states
12
U.S. cities
13
Facility City State ZIP Site status
Children's Hospital of Orange County Orange California 92868
Children's Hospital Colorado Aurora Colorado 80045
Ann & Robert Lurie Children's Hospital of Chicago Chicago Illinois 60611
Boston Children's Hospital Boston Massachusetts 02115
Children's Respiratory and Critical Care Specialists, P.A., Children's Hospitals and Clinics of Minnesota Minneapolis Minnesota 55404
The Children's Mercy Hospital Kansas City Missouri 64108
Northwell Health- Long Island Jewish Medical Center New Hyde Park New York 11040
Clinical Research of Charlotte Charlotte North Carolina 28277
Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center Cleveland Ohio 44106
Nationwide Children's Hospital Columbus Ohio 43205
Oregon Health & Science University Portland Oregon 97239
Texas Children's Hospital Houston Texas 77030
Seattle Children's Hospital Seattle Washington 98105

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03691779, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 21, 2021 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03691779 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →