Long Term Safety Study of PRALUENT
Public ClinicalTrials.gov record NCT03694197. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Long Term Safety Study of PRALUENT in Patients With Heterozygous Familial Hypercholesterolemia or With Non-Familial Hypercholesterolemia at High and Very High Cardiovascular Risk and Previously Enrolled in the Neurocognitive Function Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of the study was to evaluate the long term safety of PRALUENT in participants with heterozygous familial hypercholesterolemia (heFH) or non-familial hypercholesterolemia (FH) participants at high or very high cardiovascular risk who completed the neurocognitive function study R727-CL-1532 (NCT02957682). The secondary objectives of the study were: * To evaluate the effect of PRALUENT on low-density lipoprotein cholesterol (LDL-C) * To evaluate the effect of PRALUENT on other lipid parameters * To evaluate the effect of PRALUENT on gonadal steroid hormones
Study identification
- NCT ID
- NCT03694197
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 1,389 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 40 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 28, 2018 (Actual)
- Primary completion
- Apr 8, 2020 (Actual)
- Completion
- Apr 8, 2020 (Actual)
- Last update posted
- Jun 15, 2021
2018 – 2020
United States locations
- U.S. sites
- 57
- U.S. states
- 23
- U.S. cities
- 53
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Regeneron Research Site | Auburn | Alabama | 36830 | — |
| Regeneron Research Site | Mobile | Alabama | 36608 | — |
| Regeneron Research Site | Beverly Hills | California | 90210 | — |
| Regeneron Research Site | Los Gatos | California | 95032 | — |
| Regeneron Research Site | North Hollywood | California | 91606 | — |
| Regeneron Research Site | Port Hueneme | California | 93041 | — |
| Regeneron Research Site | Aurora | Colorado | 80012 | — |
| Regeneron Research Site | Colorado Springs | Colorado | 80906 | — |
| Regeneron Research Site | Lake Worth | Florida | 33461 | — |
| Regeneron Research Site | Miami Springs | Florida | 33166 | — |
| Regeneron Research Site | Champaign | Illinois | 61822 | — |
| Regeneron Research Site | Evansville | Indiana | 47714 | — |
| Regeneron Research Site | Indianapolis | Indiana | 46237 | — |
| Regeneron Research Site | Ames | Iowa | 50010-30144 | — |
| Regeneron Research Site | Iowa City | Iowa | 52242 | — |
| Regeneron Research Site | Waterloo | Iowa | 50702 | — |
| Regeneron Research Site | Newton | Kansas | 67114 | — |
| Regeneron Research Site | Louisville | Kentucky | 40213 | — |
| Regeneron Research Site | Bangor | Maine | 04401 | — |
| Regeneron Research Site | Baltimore | Maryland | 21229 | — |
| Regeneron Research Site | Oxon Hill | Maryland | 20745 | — |
| Regeneron Research Site | Olive Branch | Mississippi | 38654 | — |
| Regeneron Research Site | Washington | Missouri | 63090 | — |
| Regeneron Research Site | Buffalo | New York | 14215 | — |
| Regeneron Research Site | New Hyde Park | New York | 11042 | — |
| Regeneron Research Site | Cary | North Carolina | 27518 | — |
| Regeneron Research Site | Charlotte | North Carolina | 28209 | — |
| Regeneron Research Site | Charlotte | North Carolina | 28277 | — |
| Regeneron Research Site | Greensboro | North Carolina | 27401 | — |
| Regeneron Research Site | Hickory | North Carolina | 28601 | — |
| Regeneron Research Site | Raleigh | North Carolina | 27609 | — |
| Regeneron Research Site | Rocky Mount | North Carolina | 27804 | — |
| Regeneron Research Site | Salisbury | North Carolina | 28144 | — |
| Regeneron Research Site | Statesville | North Carolina | 28625 | — |
| Regeneron Research Site | Wilmington | North Carolina | 28401 | — |
| Regeneron Research Site | Winston-Salem | North Carolina | 27103 | — |
| Regeneron Research Site | Cincinnati | Ohio | 45219 | — |
| Regeneron Research Site | Cleveland | Ohio | 44122 | — |
| Regeneron Research Site | Dayton | Ohio | 45414 | — |
| Regeneron Research Site | Charleston | South Carolina | 29407 | — |
| Regeneron Research Site | Summerville | South Carolina | 29485 | — |
| Regeneron Research Site | Rapid City | South Dakota | 57701 | — |
| Regeneron Research Site | Bristol | Tennessee | 37620 | — |
| Regeneron Research Site 2 | Knoxville | Tennessee | 37760 | — |
| Regeneron Research Site 3 | Knoxville | Tennessee | 37912 | — |
| Regeneron Research Site | Knoxville | Tennessee | 37938 | — |
| Regeneron Research Site | Powell | Tennessee | 37849 | — |
| Regeneron Research Site | Dallas | Texas | 75231 | — |
| Regeneron Research Site | Houston | Texas | 77027 | — |
| Regeneron Research Site | Schertz | Texas | 78154 | — |
| Regeneron Research Site | Shavano Park | Texas | 78213 | — |
| Regeneron Research Site | Shavano Park | Texas | 78231 | — |
| Regeneron Research Site | Falls Church | Virginia | 22042 | — |
| Regeneron Research Site | Winchester | Virginia | 22601 | — |
| Regeneron Research Site | Tacoma | Washington | 98405 | — |
| Regeneron Research Site | Walla Walla | Washington | 99362 | — |
| Regeneron Research Site | Manitowoc | Wisconsin | 54220 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 66 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03694197, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 15, 2021 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03694197 live on ClinicalTrials.gov.