Extension Study to Evaluate the Safety and Tolerability of Tezepelumab in Adults and Adolescents With Severe, Uncontrolled Asthma
Public ClinicalTrials.gov record NCT03706079. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicentre, Double-blind, Randomized, Placebo Controlled, Parallel Group, Phase 3, Safety Extension Study to Evaluate the Safety and Tolerability of Tezepelumab in Adults and Adolescents With Severe Uncontrolled Asthma (DESTINATION)
Study identification
- NCT ID
- NCT03706079
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- AstraZeneca
- Industry
- Enrollment
- 951 participants
Conditions and interventions
Conditions
Interventions
- Tezepelumab Biological
- Placebo Other
Biological · Other
Eligibility (public fields only)
- Age range
- 13 Years to 81 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 6, 2019
- Primary completion
- Oct 25, 2021
- Completion
- May 17, 2022
- Last update posted
- Jun 5, 2023
2019 – 2022
United States locations
- U.S. sites
- 52
- U.S. states
- 24
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Dothan | Alabama | 36303 | — |
| Research Site | Gilbert | Arizona | 85234 | — |
| Research Site | Bakersfield | California | 93301 | — |
| Research Site | Huntington Beach | California | 92647 | — |
| Research Site | Long Beach | California | 90808 | — |
| Research Site | Los Angeles | California | 90025 | — |
| Research Site | Newport Beach | California | 92663 | — |
| Research Site | Northridge | California | 91324 | — |
| Research Site | Palm Desert | California | 92260 | — |
| Research Site | Rolling Hills Estates | California | 90274 | — |
| Research Site | Walnut Creek | California | 94598 | — |
| Research Site | Westminster | California | 92683 | — |
| Research Site | New Haven | Connecticut | 06519 | — |
| Research Site | Kissimmee | Florida | 34744 | — |
| Research Site | Kissimmee | Florida | 34746 | — |
| Research Site | Port Charlotte | Florida | 33952 | — |
| Research Site | Sarasota | Florida | 34239 | — |
| Research Site | Tampa | Florida | 33607 | — |
| Research Site | Winter Park | Florida | 32789-4681 | — |
| Research Site | Boise | Idaho | 83706 | — |
| Research Site | Zachary | Louisiana | 70791 | — |
| Research Site | White Marsh | Maryland | 21162 | — |
| Research Site | Boston | Massachusetts | 02115 | — |
| Research Site | Ann Arbor | Michigan | 48109 | — |
| Research Site | St Louis | Missouri | 63141 | — |
| Research Site | Lincoln | Nebraska | 68510 | — |
| Research Site | Las Vegas | Nevada | 89119 | — |
| Research Site | Northfield | New Jersey | 08225 | — |
| Research Site | Brooklyn | New York | 11235 | — |
| Research Site | The Bronx | New York | 10459 | — |
| Research Site | The Bronx | New York | 10461 | — |
| Research Site | Charlotte | North Carolina | 28207 | — |
| Research Site | Durham | North Carolina | 27705 | — |
| Research Site | Winston-Salem | North Carolina | 27104 | — |
| Research Site | Cincinnati | Ohio | 45229 | — |
| Research Site | Cincinnati | Ohio | 45236 | — |
| Research Site | Edmond | Oklahoma | 73034 | — |
| Research Site | Oklahoma City | Oklahoma | 73120 | — |
| Research Site | Medford | Oregon | 97504 | — |
| Research Site | Philadelphia | Pennsylvania | 19140 | — |
| Research Site | Anderson | South Carolina | 29621 | — |
| Research Site | Columbia | South Carolina | 29204 | — |
| Research Site | Greenville | South Carolina | 29607 | — |
| Research Site | Amarillo | Texas | 79109 | — |
| Research Site | Boerne | Texas | 78006 | — |
| Research Site | McKinney | Texas | 75069 | — |
| Research Site | McKinney | Texas | 75071 | — |
| Research Site | Plano | Texas | 75093 | — |
| Research Site | San Antonio | Texas | 78251 | — |
| Research Site | Manassas | Virginia | 20110 | — |
| Research Site | Cudahy | Wisconsin | 53110 | — |
| Research Site | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 128 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03706079, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 5, 2023 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03706079 live on ClinicalTrials.gov.