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Terminated Phase 2 Interventional Results available

Safety and Efficacy Study of IFX-1 in add-on to Standard of Care in GPA and MPA

ClinicalTrials.gov ID: NCT03712345

Public ClinicalTrials.gov record NCT03712345. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 7:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase II Efficacy and Safety Study of IFX-1 in Add-On to Standard of Care in Granulomatosis With Polyangiitis (GPA) and Microscopic Polyangiitis (MPA)

Study identification

NCT ID
NCT03712345
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
InflaRx GmbH
Industry
Enrollment
20 participants

Conditions and interventions

Interventions

  • IFX-1 low dose Drug
  • IFX-1 high dose Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 14, 2018
Primary completion
Sep 9, 2020
Completion
May 2, 2021
Last update posted
May 25, 2022

2018 – 2021

United States locations

U.S. sites
33
U.S. states
23
U.S. cities
33
Facility City State ZIP Site status
Mayo Clinic Scottsdale Scottsdale Arizona 85259
Loma Linda University Clinical Trial Center Loma Linda California 92354
Science Connections, LLC Doral Florida 33166
University of Miami Miami Florida 33136
Rush University Medical Center Chicago Illinois 60612
University of Kansas Medical Center Research Institute, Inc. Kansas City Kansas 66160
LSU Health Sciences Center Shreveport Shreveport Louisiana 71103
Johns Hopkins Bayview Medical Center Baltimore Maryland 21224
Massachusetts General Hospital Boston Massachusetts 02114
University Of MI Medcl Ctr-RHU Ann Arbor Michigan 48109
Henry Ford Hospital Detroit Michigan 48084
University of Minnesota Minneapolis Minnesota 55414
Mayo Clinic Rochester Minnesota 55905
Washington University St Louis Missouri 63110
University of New Mexico Albuquerque New Mexico 87131
Northwell Health, LLC PRIME New Hyde Park New York 11042
Hospital for Special Surgery New York New York 10021
University of Rochester Medical Center - Strong Memorial Hospital Rochester New York 14642
UNC Kidney Center, UNC-CH Division of Nephrology and Hypertension Chapel Hill North Carolina 27599-7155
Trinity Medical Group Minot North Dakota 58701
Ohio State University Clinical Trials Management Office Columbus Ohio 43203
Oregon Health & Science University Portland Oregon 97239
BRCR Medical Center, Inc. Camp Hill Pennsylvania 17011
Altoona Center for Clinical Research, P.C. Duncansville Pennsylvania 16635
University of Pennsylvania Philadelphia Pennsylvania 19104
Rhode Island Hospital Providence Rhode Island 02903
Low Country Rheumatology, PA North Charleston South Carolina 29406
Adriana Pop Moody Clinic PA Corpus Christi Texas 78404
Texas Health Resources Dallas Texas 75287
Texas Research Institute Fort Worth Texas 76104
Pioneer Research Solutions, Inc. Houston Texas 77099
UVA University Physicians Charlottesville Charlottesville Virginia 22903
West Virginia University Morgantown West Virginia 26506

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03712345, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 25, 2022 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03712345 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →