Safety and Efficacy Study of IFX-1 in add-on to Standard of Care in GPA and MPA
Public ClinicalTrials.gov record NCT03712345. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase II Efficacy and Safety Study of IFX-1 in Add-On to Standard of Care in Granulomatosis With Polyangiitis (GPA) and Microscopic Polyangiitis (MPA)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to investigate the safety and tolerability of two dose regimens of IFX-1 as add-on to standard of care (SOC) in subjects with GPA and MPA compared with placebo.
Study identification
- NCT ID
- NCT03712345
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 20 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 15, 2018 (Actual)
- Primary completion
- Sep 10, 2020 (Actual)
- Completion
- May 3, 2021 (Actual)
- Last update posted
- May 26, 2022
2018 – 2021
United States locations
- U.S. sites
- 33
- U.S. states
- 23
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Scottsdale | Scottsdale | Arizona | 85259 | — |
| Loma Linda University Clinical Trial Center | Loma Linda | California | 92354 | — |
| Science Connections, LLC | Doral | Florida | 33166 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Kansas Medical Center Research Institute, Inc. | Kansas City | Kansas | 66160 | — |
| LSU Health Sciences Center Shreveport | Shreveport | Louisiana | 71103 | — |
| Johns Hopkins Bayview Medical Center | Baltimore | Maryland | 21224 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| University Of MI Medcl Ctr-RHU | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Hospital | Detroit | Michigan | 48084 | — |
| University of Minnesota | Minneapolis | Minnesota | 55414 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| University of New Mexico | Albuquerque | New Mexico | 87131 | — |
| Northwell Health, LLC PRIME | New Hyde Park | New York | 11042 | — |
| Hospital for Special Surgery | New York | New York | 10021 | — |
| University of Rochester Medical Center - Strong Memorial Hospital | Rochester | New York | 14642 | — |
| UNC Kidney Center, UNC-CH Division of Nephrology and Hypertension | Chapel Hill | North Carolina | 27599-7155 | — |
| Trinity Medical Group | Minot | North Dakota | 58701 | — |
| Ohio State University Clinical Trials Management Office | Columbus | Ohio | 43203 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| BRCR Medical Center, Inc. | Camp Hill | Pennsylvania | 17011 | — |
| Altoona Center for Clinical Research, P.C. | Duncansville | Pennsylvania | 16635 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Low Country Rheumatology, PA | North Charleston | South Carolina | 29406 | — |
| Adriana Pop Moody Clinic PA | Corpus Christi | Texas | 78404 | — |
| Texas Health Resources | Dallas | Texas | 75287 | — |
| Texas Research Institute | Fort Worth | Texas | 76104 | — |
| Pioneer Research Solutions, Inc. | Houston | Texas | 77099 | — |
| UVA University Physicians Charlottesville | Charlottesville | Virginia | 22903 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03712345, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 26, 2022 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03712345 live on ClinicalTrials.gov.