A Long Term Study to Find Out if Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease
Public ClinicalTrials.gov record NCT03714815. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Long-term, Multicenter, Single-arm, Open-label Extension of the SERENADE Study, to Assess the Safety and Efficacy of Macitentan in Subjects With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease
Study identification
- NCT ID
- NCT03714815
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Actelion
- Industry
- Enrollment
- 91 participants
Conditions and interventions
Interventions
- macitentan 10 mg Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 6, 2018
- Primary completion
- Oct 11, 2021
- Completion
- Oct 11, 2021
- Last update posted
- Feb 3, 2025
2018 – 2021
United States locations
- U.S. sites
- 11
- U.S. states
- 11
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| South Denver Cardiology Associates PC | Littleton | Colorado | 80120 | — |
| Northwestern University Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| University Of Iowa - Hospitals & Clinics | Iowa City | Iowa | 52242-1081 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Washington University School Of Medicine | St Louis | Missouri | 63110 | — |
| Allegheny | Pittsburgh | Pennsylvania | 15212 | — |
| North Dallas Research Associates | McKinney | Texas | 75069 | — |
| Inova Heart and Vascular Institute | Falls Church | Virginia | 22042 | — |
| MultiCare Health System | Tacoma | Washington | 98405 | — |
| Aurora Saint Lukes Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 33 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03714815, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 3, 2025 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03714815 live on ClinicalTrials.gov.